Large-scale genomic analyses link reproductive ageing to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair
Identifieur interne : 002B98 ( Main/Exploration ); précédent : 002B97; suivant : 002B99Large-scale genomic analyses link reproductive ageing to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair
Auteurs : Felix R. Day [Royaume-Uni] ; Katherine S. Ruth [Royaume-Uni] ; Deborah J. Thompson [Royaume-Uni] ; Kathryn L. Lunetta [États-Unis] ; Natalia Pervjakova [Estonie] ; Daniel I. Chasman [États-Unis] ; Lisette Stolk [Pays-Bas] ; Hilary K. Finucane [États-Unis] ; Patrick Sulem [Islande] ; Brendan Bulik-Sullivan [États-Unis] ; T Nu Esko [Estonie, États-Unis] ; Andrew D. Johnson [États-Unis] ; Cathy E. Elks [Royaume-Uni] ; Nora Franceschini [États-Unis] ; Chunyan He [États-Unis] ; Elisabeth Altmaier [Allemagne] ; Jennifer A. Brody [États-Unis] ; Lude L. Franke [Pays-Bas] ; Jennifer E. Huffman [États-Unis, Royaume-Uni] ; Margaux F. Keller [États-Unis] ; Patrick F. Mcardle [États-Unis] ; Teresa Nutile [Italie] ; Eleonora Porcu [Italie, États-Unis] ; Antonietta Robino [Italie] ; Lynda M. Rose [États-Unis] ; Ursula M. Schick [États-Unis] ; Jennifer A. Smith [États-Unis] ; Alexander Teumer [Allemagne] ; Michela Traglia [Italie] ; Dragana Vuckovic [Italie] ; Jie Yao [États-Unis] ; Wei Zhao [États-Unis] ; Eva Albrecht [Allemagne] ; Najaf Amin [Pays-Bas] ; Tanguy Corre [Suisse] ; Jouke-Jan Hottenga [Pays-Bas] ; Massimo Mangino [Royaume-Uni] ; Albert V. Smith [Islande] ; Toshiko Tanaka [États-Unis] ; Goncalo Abecasis [États-Unis] ; Irene L. Andrulis [Canada] ; Hoda Anton-Culver [États-Unis] ; Antonis C. Antoniou [Royaume-Uni] ; Volker Arndt [Allemagne] ; Alice M. Arnold [États-Unis] ; Caterina Barbieri [Italie] ; Matthias W. Beckmann [Allemagne] ; Alicia Beeghly-Fadiel [États-Unis] ; Javier Benitez [Espagne] ; Leslie Bernstein [États-Unis] ; Suzette J. Bielinski [États-Unis] ; Carl Blomqvist [Finlande] ; Eric Boerwinkle [États-Unis] ; Natalia V. Bogdanova [Allemagne] ; Stig E. Bojesen [Danemark] ; Manjeet K. Bolla [Royaume-Uni] ; Anne-Lise Borresen-Dale [Norvège] ; Thibaud S. Boutin [Royaume-Uni] ; Hiltrud Brauch [Allemagne] ; Hermann Brenner [Allemagne] ; Thomas Brüning [Allemagne] ; Barbara Burwinkel [Allemagne] ; Archie Campbell [Royaume-Uni] ; Harry Campbell [Royaume-Uni] ; Stephen J. Chanock [États-Unis] ; J. Ross Chapman [Royaume-Uni] ; Yii-Der Ida Chen [États-Unis] ; Georgia Chenevix-Trench [Australie] ; Fergus J. Couch [États-Unis] ; Andrea D. Coviello [États-Unis] ; Angela Cox [Royaume-Uni] ; Kamila Czene [Suède] ; Hatef Darabi [Suède] ; Immaculata De Vivo [États-Unis] ; Ellen W. Demerath [États-Unis] ; Joe Dennis [Royaume-Uni] ; Peter Devilee [Pays-Bas] ; Thilo Dörk [Allemagne] ; Isabel Dos-Santos-Silva [Royaume-Uni] ; Alison M. Dunning [Royaume-Uni] ; John D. Eicher [États-Unis] ; Peter A. Fasching [Allemagne, États-Unis] ; Jessica D. Faul [États-Unis] ; Jonine Figueroa [États-Unis] ; Dieter Flesch-Janys [Allemagne] ; Ilaria Gandin [Italie] ; Melissa E. Garcia [États-Unis] ; Montserrat García-Closas [Royaume-Uni] ; Graham G. Giles [Australie] ; Giorgia G. Girotto [Italie] ; Mark S. Goldberg [Canada] ; Anna González-Neira [Espagne] ; Mark O. Goodarzi [États-Unis] ; Megan L. Grove [États-Unis] ; Daniel F. Gudbjartsson [Islande] ; Pascal Guénel [France] ; Xiuqing Guo [États-Unis] ; Christopher A. Haiman [États-Unis] ; Per Hall [Suède] ; Ute Hamann [Allemagne] ; Brian E. Henderson [États-Unis] ; Lynne J. Hocking [Royaume-Uni] ; Albert Hofman [Pays-Bas] ; Georg Homuth [Allemagne] ; Maartje J. Hooning [Pays-Bas] ; John L. Hopper [Australie] ; Frank B. Hu [États-Unis] ; Jinyan Huang [République populaire de Chine] ; Keith Humphreys [Suède] ; David J. Hunter [États-Unis] ; Anna Jakubowska [Pologne] ; Samuel E. Jones [Royaume-Uni] ; Maria Kabisch [Allemagne] ; David Karasik [États-Unis] ; Julia A. Knight [Canada] ; Ivana Kolcic [Croatie] ; Charles Kooperberg [États-Unis] ; Veli-Matti Kosma [Finlande] ; Jennifer Kriebel [Allemagne] ; Vessela Kristensen [Norvège] ; Diether Lambrechts [Belgique] ; Claudia Langenberg [Royaume-Uni] ; Jingmei Li [Suède] ; Xin Li [États-Unis] ; Sara Lindström [États-Unis] ; Yongmei Liu ; Jian N Luan [Royaume-Uni] ; Jan Lubinski [Pologne] ; Reedik M Gi [Estonie] ; Arto Mannermaa [Finlande] ; Judith Manz [Allemagne] ; Sara Margolin [Suède] ; Jonathan Marten [Royaume-Uni] ; Nicholas G. Martin [Australie] ; Corrado Masciullo [Italie] ; Alfons Meindl [Allemagne] ; Kyriaki Michailidou [Royaume-Uni] ; Evelin Mihailov [Estonie] ; Lili Milani [Estonie] ; Roger L. Milne [Australie] ; Martina Müller-Nurasyid [Allemagne] ; Michael Nalls [États-Unis] ; Ben M. Neale [États-Unis] ; Heli Nevanlinna [Finlande] ; Patrick Neven [Belgique] ; Anne B. Newman [États-Unis] ; B Rge G. Nordestgaard [Danemark] ; Janet E. Olson [États-Unis] ; Sandosh Padmanabhan [Royaume-Uni] ; Paolo Peterlongo [Italie] ; Ulrike Peters [États-Unis] ; Astrid Petersmann [Allemagne] ; Julian Peto [Royaume-Uni] ; Paul D. P. Pharoah [Royaume-Uni] ; Nicola N. Pirastu [Italie] ; Ailith Pirie [Royaume-Uni] ; Giorgio Pistis [Italie, États-Unis] ; Ozren Polasek [Croatie] ; David Porteous [Royaume-Uni] ; Bruce M. Psaty [États-Unis] ; Katri Pylk S [Finlande] ; Paolo Radice [Italie] ; Leslie J. Raffel [États-Unis] ; Fernando Rivadeneira [Pays-Bas] ; Igor Rudan [Royaume-Uni] ; Anja Rudolph [Allemagne] ; Daniela Ruggiero [Italie] ; Cinzia F. Sala [Italie] ; Serena Sanna [Italie] ; Elinor J. Sawyer [Royaume-Uni] ; David Schlessinger [États-Unis] ; Marjanka K. Schmidt [Pays-Bas] ; Frank Schmidt [Allemagne] ; Rita K. Schmutzler [Allemagne] ; Minouk J. Schoemaker [Royaume-Uni] ; Robert A. Scott [Royaume-Uni] ; Caroline M. Seynaeve [Pays-Bas] ; Jacques Simard [Canada] ; Rossella Sorice [Italie] ; Melissa C. Southey [Australie] ; Doris Stöckl [Allemagne] ; Konstantin Strauch [Allemagne] ; Anthony Swerdlow [Royaume-Uni] ; Kent D. Taylor [États-Unis] ; Unnur Thorsteinsdottir [Islande] ; Amanda E. Toland [États-Unis] ; Ian Tomlinson [Royaume-Uni] ; Thérèse Truong [France] ; Laufey Tryggvadottir [Islande] ; Stephen T. Turner [États-Unis] ; Diego Vozzi [Italie] ; Qin Wang [Royaume-Uni] ; Melissa Wellons [États-Unis] ; Gonneke Willemsen [Pays-Bas] ; James F. Wilson [Royaume-Uni] ; Robert Winqvist [Finlande] ; Bruce B. H. R. Wolffenbuttel [Pays-Bas] ; Alan F. Wright [Royaume-Uni] ; Drakoulis Yannoukakos [Grèce] ; Tatijana Zemunik [Croatie] ; Wei Zheng [États-Unis] ; Marek Zygmunt [Allemagne] ; Sven Bergmann [Suisse] ; Dorret I. Boomsma [Pays-Bas] ; Julie E. Buring [États-Unis] ; Luigi Ferrucci [États-Unis] ; Grant W. Montgomery [Australie] ; Vilmundur Gudnason [Islande] ; Tim D. Spector [Royaume-Uni] ; Cornelia M. Van Duijn [Pays-Bas] ; Behrooz Z. Alizadeh [Pays-Bas] ; Marina Ciullo [Italie] ; Laura Crisponi [Italie] ; Douglas F. Easton [Royaume-Uni] ; Paolo P. Gasparini [Italie] ; Christian Gieger [Allemagne] ; Tamara B. Harris [États-Unis] ; Caroline Hayward [Royaume-Uni] ; Sharon L. R. Kardia [États-Unis] ; Peter Kraft [États-Unis] ; Barbara Mcknight [États-Unis] ; Andres Metspalu [Estonie] ; Alanna C. Morrison [États-Unis] ; Alex P. Reiner [États-Unis] ; Paul M. Ridker [États-Unis] ; Jerome I. Rotter [États-Unis] ; Daniela Toniolo [Italie] ; André G. Uitterlinden [Pays-Bas] ; Sheila Ulivi [Italie] ; Henry Völzke [Allemagne] ; Nicholas J. Wareham [Royaume-Uni] ; David R. Weir [États-Unis] ; Laura M. Yerges-Armstrong [États-Unis] ; Alkes L. Price [États-Unis] ; Kari Stefansson [Islande] ; Jenny A. Visser [Pays-Bas] ; Ken K. Ong [Royaume-Uni] ; Jenny Chang-Claude [Allemagne] ; Joanne M. Murabito [États-Unis] ; John R. B. Perry [Royaume-Uni] ; Anna Murray [Royaume-Uni]Source :
- Nature genetics [ 1061-4036 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Facteurs de l'âge, Femelle, Génomique (), Génotype, Humains, Hypothalamus (métabolisme), Modèles génétiques, Ménopause (génétique), Phénotype, Protéine BRCA1 (génétique), Prédisposition génétique à une maladie (génétique), Reproduction (génétique), Réparation de l'ADN, Réseaux de régulation génique (génétique), Transduction du signal (génétique), Tumeurs du sein (génétique), Variation génétique, Vieillissement (génétique), Étude d'association pangénomique ().
- MESH :
- génétique : Ménopause, Protéine BRCA1, Prédisposition génétique à une maladie, Reproduction, Réseaux de régulation génique, Transduction du signal, Tumeurs du sein, Vieillissement.
- métabolisme : Hypothalamus.
- Adulte, Adulte d'âge moyen, Facteurs de l'âge, Femelle, Génomique, Génotype, Humains, Modèles génétiques, Phénotype, Réparation de l'ADN, Variation génétique, Étude d'association pangénomique.
English descriptors
- KwdEn :
- Adult, Age Factors, Aging (genetics), BRCA1 Protein (genetics), Breast Neoplasms (genetics), DNA Repair, Female, Gene Regulatory Networks (genetics), Genetic Predisposition to Disease (genetics), Genetic Variation, Genome-Wide Association Study (methods), Genomics (methods), Genotype, Humans, Hypothalamus (metabolism), Menopause (genetics), Middle Aged, Models, Genetic, Phenotype, Reproduction (genetics), Signal Transduction (genetics).
- MESH :
- chemical , genetics : BRCA1 Protein.
- genetics : Aging, Breast Neoplasms, Gene Regulatory Networks, Genetic Predisposition to Disease, Menopause, Reproduction, Signal Transduction.
- metabolism : Hypothalamus.
- methods : Genome-Wide Association Study, Genomics.
- Adult, Age Factors, DNA Repair, Female, Genetic Variation, Genotype, Humans, Middle Aged, Models, Genetic, Phenotype.
Abstract
Menopause timing has a substantial impact on infertility and risk of disease, including breast cancer, but the underlying mechanisms are poorly understood. We report a dual strategy in ~70,000 women to identify common and low-frequency protein-coding variation associated with age at natural menopause (ANM). We identified 44 regions with common variants, including two harbouring additional rare missense alleles of large effect. We found enrichment of signals in/near genes involved in delayed puberty, highlighting the first molecular links between the onset and end of reproductive lifespan. Pathway analyses revealed a major association with DNA damage-response (DDR) genes, including the first common coding variant in
Url:
DOI: 10.1038/ng.3412
PubMed: 26414677
PubMed Central: 4661791
Affiliations:
- Allemagne, Australie, Belgique, Canada, Croatie, Danemark, Espagne, Estonie, Finlande, France, Grèce, Islande, Italie, Norvège, Pays-Bas, Pologne, Royaume-Uni, République populaire de Chine, Suisse, Suède, États-Unis
- Angleterre, Angleterre de l'Est, Attique (région), Bade-Wurtemberg, Basse-Saxe, Bavière, Californie, Canton de Vaud, Caroline du Nord, Communauté de Madrid, District de Haute-Bavière, District de Karlsruhe, District de Moyenne-Franconie, District de Stuttgart, District de Tübingen, Grand Londres, Groningue (province), Hambourg, Hollande-Méridionale, Hollande-Septentrionale, Hovedstaden, Indiana, Lombardie, Maryland, Massachusetts, Michigan, Minnesota, Ohio, Ontario, Oxfordshire, Pennsylvanie, Québec, Svealand, Tennessee, Texas, Victoria (État), Washington (État), Écosse, Østlandet
- Amsterdam, Athènes, Cambridge, Copenhague, Erlangen, Glasgow, Groningue, Groningue (ville), Hambourg, Hanovre, Heidelberg, Lausanne, Londres, Los Angeles, Madrid, Melbourne, Milan, Montréal, Munich, Oslo, Oxford, Pittsburgh, Rotterdam, Seattle, Stockholm, Stuttgart, Toronto, Tübingen, Édimbourg
- Université McGill, Université d'Oxford, Université d'Édimbourg, Université de Californie du Sud, Université de Cambridge, Université de Glasgow, Université de Groningue, Université de Melbourne, Université de Pittsburgh, Université de Toronto, Université de Washington, Université technique de Munich
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Le document en format XML
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Boston, Massachusetts 02118, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Boston University School of Public Health, Department of Biostatistics. 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Finucane</name><affiliation wicri:level="2"><nlm:aff id="A12">Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A13">Department of Mathematics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139-4307, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Mathematics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139-4307</wicri:regionArea><wicri:noRegion>Massachusetts 02139-4307</wicri:noRegion></affiliation></author><author><name sortKey="Sulem, Patrick" sort="Sulem, Patrick" uniqKey="Sulem P" first="Patrick" last="Sulem">Patrick Sulem</name><affiliation wicri:level="1"><nlm:aff id="A14">deCODE genetics/Amgen, Inc., IS-101 Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE genetics/Amgen, Inc., IS-101 Reykjavik</wicri:regionArea><wicri:noRegion>IS-101 Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Bulik Sullivan, Brendan" sort="Bulik Sullivan, Brendan" uniqKey="Bulik Sullivan B" first="Brendan" last="Bulik-Sullivan">Brendan Bulik-Sullivan</name><affiliation wicri:level="1"><nlm:aff id="A15">Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142</wicri:regionArea><wicri:noRegion>Massachusetts 02142</wicri:noRegion></affiliation><affiliation wicri:level="2"><nlm:aff id="A16">Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A17">Medical and Population Genetics, Broad Institute, Cambridge, MA 02142, US</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical and Population Genetics, Broad Institute, Cambridge, MA 02142</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Esko, T Nu" sort="Esko, T Nu" uniqKey="Esko T" first="T Nu" last="Esko">T Nu Esko</name><affiliation wicri:level="1"><nlm:aff id="A6">Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu, 51010</wicri:regionArea><wicri:noRegion>51010</wicri:noRegion></affiliation><affiliation wicri:level="2"><nlm:aff id="A18">Division of Endocrinology, Boston Children’s Hospital, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Endocrinology, Boston Children’s Hospital, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A19">Department of Genetics, Harvard Medical School, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, Harvard Medical School, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A20">Broad Institute of the Massachusetts Institute of Technology and Harvard University, 140 Cambridge 02142, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Broad Institute of the Massachusetts Institute of Technology and Harvard University, 140 Cambridge 02142, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Johnson, Andrew D" sort="Johnson, Andrew D" uniqKey="Johnson A" first="Andrew D." last="Johnson">Andrew D. Johnson</name><affiliation wicri:level="1"><nlm:aff id="A5">NHLBI’s and Boston University’s Framingham Heart Study, Framingham, Massachusetts 01702-5827, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>NHLBI’s and Boston University’s Framingham Heart Study, Framingham, Massachusetts 01702-5827</wicri:regionArea><wicri:noRegion>Massachusetts 01702-5827</wicri:noRegion></affiliation></author><author><name sortKey="Elks, Cathy E" sort="Elks, Cathy E" uniqKey="Elks C" first="Cathy E." last="Elks">Cathy E. Elks</name><affiliation wicri:level="1"><nlm:aff id="A1"> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ</wicri:regionArea><wicri:noRegion>CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Franceschini, Nora" sort="Franceschini, Nora" uniqKey="Franceschini N" first="Nora" last="Franceschini">Nora Franceschini</name><affiliation wicri:level="2"><nlm:aff id="A21">Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27599, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27599</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="He, Chunyan" sort="He, Chunyan" uniqKey="He C" first="Chunyan" last="He">Chunyan He</name><affiliation wicri:level="2"><nlm:aff id="A22">Department of Epidemiology, Indiana University Richard M. Fairbanks School of Public Health, Indianapolis, IN 46202, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Indiana University Richard M. Fairbanks School of Public Health, Indianapolis, IN 46202</wicri:regionArea><placeName><region type="state">Indiana</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A23">Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, IN 46202, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, IN 46202</wicri:regionArea><placeName><region type="state">Indiana</region></placeName></affiliation></author><author><name sortKey="Altmaier, Elisabeth" sort="Altmaier, Elisabeth" uniqKey="Altmaier E" first="Elisabeth" last="Altmaier">Elisabeth Altmaier</name><affiliation wicri:level="1"><nlm:aff id="A24">Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A25">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A26">Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Brody, Jennifer A" sort="Brody, Jennifer A" uniqKey="Brody J" first="Jennifer A." last="Brody">Jennifer A. Brody</name><affiliation wicri:level="4"><nlm:aff id="A27">Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle Washington 98101 USA</nlm:aff><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Franke, Lude L" sort="Franke, Lude L" uniqKey="Franke L" first="Lude L." last="Franke">Lude L. Franke</name><affiliation wicri:level="4"><nlm:aff id="A28">Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region><settlement type="city">Groningue (ville)</settlement></placeName><orgName type="university">Université de Groningue</orgName></affiliation></author><author><name sortKey="Huffman, Jennifer E" sort="Huffman, Jennifer E" uniqKey="Huffman J" first="Jennifer E." last="Huffman">Jennifer E. Huffman</name><affiliation wicri:level="1"><nlm:aff id="A5">NHLBI’s and Boston University’s Framingham Heart Study, Framingham, Massachusetts 01702-5827, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>NHLBI’s and Boston University’s Framingham Heart Study, Framingham, Massachusetts 01702-5827</wicri:regionArea><wicri:noRegion>Massachusetts 01702-5827</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A29">Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Keller, Margaux F" sort="Keller, Margaux F" uniqKey="Keller M" first="Margaux F." last="Keller">Margaux F. Keller</name><affiliation wicri:level="2"><nlm:aff id="A30">Merck Pharmaceuticals, 33 Avenue Louis Pasteur, Boston, MA 02115, United States</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Merck Pharmaceuticals, 33 Avenue Louis Pasteur, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Mcardle, Patrick F" sort="Mcardle, Patrick F" uniqKey="Mcardle P" first="Patrick F." last="Mcardle">Patrick F. Mcardle</name><affiliation wicri:level="2"><nlm:aff id="A31">Program in Personalized Medicine, Division of Endocrinology, Diabetes and Nutrition - University of Maryland School of Medicine, USA. Baltimore, MD 21201</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Program in Personalized Medicine, Division of Endocrinology, Diabetes and Nutrition - University of Maryland School of Medicine, USA. Baltimore</wicri:cityArea></affiliation></author><author><name sortKey="Nutile, Teresa" sort="Nutile, Teresa" uniqKey="Nutile T" first="Teresa" last="Nutile">Teresa Nutile</name><affiliation wicri:level="1"><nlm:aff id="A32">Institute of Genetics and Biophysics - CNR, via Pietro Castellino 111, 80131, Naples, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Genetics and Biophysics - CNR, via Pietro Castellino 111, 80131, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Porcu, Eleonora" sort="Porcu, Eleonora" uniqKey="Porcu E" first="Eleonora" last="Porcu">Eleonora Porcu</name><affiliation wicri:level="1"><nlm:aff id="A33">Institute of Genetics and Biomedical Research, National Research Council, Cagliari, 09042 Sardinia, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Genetics and Biomedical Research, National Research Council, Cagliari, 09042 Sardinia</wicri:regionArea><wicri:noRegion>09042 Sardinia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A34">University of Sassari, Department of Biomedical Sciences, Sassari, 07100 Sassari, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>University of Sassari, Department of Biomedical Sciences, Sassari, 07100 Sassari</wicri:regionArea><wicri:noRegion>07100 Sassari</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A35">Center for Statistical Genetics, Ann Arbor, University of Michigan, Michigan 48109-2029, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Ann Arbor, University of Michigan, Michigan 48109-2029</wicri:regionArea><wicri:noRegion>Michigan 48109-2029</wicri:noRegion></affiliation></author><author><name sortKey="Robino, Antonietta" sort="Robino, Antonietta" uniqKey="Robino A" first="Antonietta" last="Robino">Antonietta Robino</name><affiliation wicri:level="1"><nlm:aff id="A36">Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste</wicri:regionArea><wicri:noRegion>34137 Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Rose, Lynda M" sort="Rose, Lynda M" uniqKey="Rose L" first="Lynda M." last="Rose">Lynda M. Rose</name><affiliation wicri:level="2"><nlm:aff id="A8">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, MA 02215</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Division of Preventive Medicine, Brigham and Women’s Hospital, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Schick, Ursula M" sort="Schick, Ursula M" uniqKey="Schick U" first="Ursula M." last="Schick">Ursula M. Schick</name><affiliation wicri:level="2"><nlm:aff id="A37">Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Seattle, WA 98109-1024, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Seattle, WA 98109-1024</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Smith, Jennifer A" sort="Smith, Jennifer A" uniqKey="Smith J" first="Jennifer A." last="Smith">Jennifer A. Smith</name><affiliation wicri:level="2"><nlm:aff id="A38">Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name><affiliation wicri:level="1"><nlm:aff id="A39">Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Traglia, Michela" sort="Traglia, Michela" uniqKey="Traglia M" first="Michela" last="Traglia">Michela Traglia</name><affiliation wicri:level="1"><nlm:aff id="A40">Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano</wicri:regionArea><wicri:noRegion>20132 Milano</wicri:noRegion></affiliation></author><author><name sortKey="Vuckovic, Dragana" sort="Vuckovic, Dragana" uniqKey="Vuckovic D" first="Dragana" last="Vuckovic">Dragana Vuckovic</name><affiliation wicri:level="1"><nlm:aff id="A36">Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste</wicri:regionArea><wicri:noRegion>34137 Trieste</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A41">Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, 34149 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, 34149 Trieste</wicri:regionArea><wicri:noRegion>34149 Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Yao, Jie" sort="Yao, Jie" uniqKey="Yao J" first="Jie" last="Yao">Jie Yao</name><affiliation wicri:level="2"><nlm:aff id="A42">The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Zhao, Wei" sort="Zhao, Wei" uniqKey="Zhao W" first="Wei" last="Zhao">Wei Zhao</name><affiliation wicri:level="2"><nlm:aff id="A38">Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Albrecht, Eva" sort="Albrecht, Eva" uniqKey="Albrecht E" first="Eva" last="Albrecht">Eva Albrecht</name><affiliation wicri:level="1"><nlm:aff id="A25">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Amin, Najaf" sort="Amin, Najaf" uniqKey="Amin N" first="Najaf" last="Amin">Najaf Amin</name><affiliation wicri:level="3"><nlm:aff id="A43">Genetic Epidemiology Unit Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Genetic Epidemiology Unit Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Corre, Tanguy" sort="Corre, Tanguy" uniqKey="Corre T" first="Tanguy" last="Corre">Tanguy Corre</name><affiliation wicri:level="1"><nlm:aff id="A44">Department of Medical Genetics, University of Lausanne, CH-1005 Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Medical Genetics, University of Lausanne, CH-1005 Lausanne</wicri:regionArea><wicri:noRegion>CH-1005 Lausanne</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A45">Swiss Institute of Bioinformatics, CH-1015, Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Swiss Institute of Bioinformatics, CH-1015, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Hottenga, Jouke Jan" sort="Hottenga, Jouke Jan" uniqKey="Hottenga J" first="Jouke-Jan" last="Hottenga">Jouke-Jan Hottenga</name><affiliation wicri:level="3"><nlm:aff id="A46">Department of Biological Psychology, VU University Amsterdam, van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, VU University Amsterdam, van der Boechorststraat 1, 1081 BT, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name><affiliation wicri:level="1"><nlm:aff id="A47">Department of Twin Research and Genetic Epidemiology, King’s College London, London SE1 7EH, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London SE1 7EH</wicri:regionArea><wicri:noRegion>London SE1 7EH</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A48">National Institute for Health Research (NIHR) Biomedical Research Centre at Guy’s and St. Thomas’ Foundation Trust, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>National Institute for Health Research (NIHR) Biomedical Research Centre at Guy’s and St. Thomas’ Foundation Trust, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Smith, Albert V" sort="Smith, Albert V" uniqKey="Smith A" first="Albert V." last="Smith">Albert V. Smith</name><affiliation wicri:level="1"><nlm:aff id="A49">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A50">Faculty of Medicine, University of Iceland, IS-101 Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, IS-101 Reykjavik</wicri:regionArea><wicri:noRegion>IS-101 Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name><affiliation wicri:level="1"><nlm:aff id="A51">Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21224, United States of America</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21224</wicri:regionArea><wicri:noRegion>Maryland 21224</wicri:noRegion></affiliation></author><author><name sortKey="Abecasis, Goncalo" sort="Abecasis, Goncalo" uniqKey="Abecasis G" first="Goncalo" last="Abecasis">Goncalo Abecasis</name><affiliation wicri:level="1"><nlm:aff id="A35">Center for Statistical Genetics, Ann Arbor, University of Michigan, Michigan 48109-2029, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Ann Arbor, University of Michigan, Michigan 48109-2029</wicri:regionArea><wicri:noRegion>Michigan 48109-2029</wicri:noRegion></affiliation></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name><affiliation wicri:level="1"><nlm:aff id="A52">Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario M5G 1X5</wicri:regionArea><wicri:noRegion>Ontario M5G 1X5</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A53">Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Molecular Genetics, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Anton Culver, Hoda" sort="Anton Culver, Hoda" uniqKey="Anton Culver H" first="Hoda" last="Anton-Culver">Hoda Anton-Culver</name><affiliation wicri:level="2"><nlm:aff id="A54">Department of Epidemiology, University of California Irvine, Irvine, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of California Irvine, Irvine, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Antoniou, Antonis C" sort="Antoniou, Antonis C" uniqKey="Antoniou A" first="Antonis C." last="Antoniou">Antonis C. Antoniou</name><affiliation wicri:level="4"><nlm:aff id="A3">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Arndt, Volker" sort="Arndt, Volker" uniqKey="Arndt V" first="Volker" last="Arndt">Volker Arndt</name><affiliation wicri:level="3"><nlm:aff id="A55">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Arnold, Alice M" sort="Arnold, Alice M" uniqKey="Arnold A" first="Alice M." last="Arnold">Alice M. Arnold</name><affiliation wicri:level="4"><nlm:aff id="A56">Department of Biostatistics, University of Washington, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, University of Washington, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Barbieri, Caterina" sort="Barbieri, Caterina" uniqKey="Barbieri C" first="Caterina" last="Barbieri">Caterina Barbieri</name><affiliation wicri:level="1"><nlm:aff id="A36">Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste</wicri:regionArea><wicri:noRegion>34137 Trieste</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A40">Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano</wicri:regionArea><wicri:noRegion>20132 Milano</wicri:noRegion></affiliation></author><author><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W." last="Beckmann">Matthias W. Beckmann</name><affiliation wicri:level="3"><nlm:aff id="A57">Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen</wicri:regionArea><placeName><settlement type="city">Erlangen</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Moyenne-Franconie</region></placeName></affiliation></author><author><name sortKey="Beeghly Fadiel, Alicia" sort="Beeghly Fadiel, Alicia" uniqKey="Beeghly Fadiel A" first="Alicia" last="Beeghly-Fadiel">Alicia Beeghly-Fadiel</name><affiliation wicri:level="2"><nlm:aff id="A58">Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benitez">Javier Benitez</name><affiliation wicri:level="3"><nlm:aff id="A59">Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A60">Centro de Investigación en Red de Enfermedades Raras (CIBERER), Valencia, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Centro de Investigación en Red de Enfermedades Raras (CIBERER), Valencia</wicri:regionArea><wicri:noRegion>Valencia</wicri:noRegion></affiliation></author><author><name sortKey="Bernstein, Leslie" sort="Bernstein, Leslie" uniqKey="Bernstein L" first="Leslie" last="Bernstein">Leslie Bernstein</name><affiliation wicri:level="2"><nlm:aff id="A61">Beckman Research Institute of City of Hope, Duarte, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Beckman Research Institute of City of Hope, Duarte, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Bielinski, Suzette J" sort="Bielinski, Suzette J" uniqKey="Bielinski S" first="Suzette J." last="Bielinski">Suzette J. Bielinski</name><affiliation wicri:level="2"><nlm:aff id="A62">Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Blomqvist, Carl" sort="Blomqvist, Carl" uniqKey="Blomqvist C" first="Carl" last="Blomqvist">Carl Blomqvist</name><affiliation wicri:level="1"><nlm:aff id="A63">Department of Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><affiliation wicri:level="2"><nlm:aff id="A64">Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A65">Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Bogdanova, Natalia V" sort="Bogdanova, Natalia V" uniqKey="Bogdanova N" first="Natalia V." last="Bogdanova">Natalia V. Bogdanova</name><affiliation wicri:level="3"><nlm:aff id="A66">Department of Radiation Oncology, Hannover Medical School, Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiation Oncology, Hannover Medical School, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Bojesen, Stig E" sort="Bojesen, Stig E" uniqKey="Bojesen S" first="Stig E." last="Bojesen">Stig E. Bojesen</name><affiliation wicri:level="3"><nlm:aff id="A67">Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A68">Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Bolla, Manjeet K" sort="Bolla, Manjeet K" uniqKey="Bolla M" first="Manjeet K." last="Bolla">Manjeet K. Bolla</name><affiliation wicri:level="4"><nlm:aff id="A3">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Borresen Dale, Anne Lise" sort="Borresen Dale, Anne Lise" uniqKey="Borresen Dale A" first="Anne-Lise" last="Borresen-Dale">Anne-Lise Borresen-Dale</name><affiliation wicri:level="3"><nlm:aff id="A69">Department of Genetics, Institute for Cancer Research, Radiumhospitalet, Oslo University Hospital, Oslo University Hospital, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Genetics, Institute for Cancer Research, Radiumhospitalet, Oslo University Hospital, Oslo University Hospital, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A70">Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Boutin, Thibaud S" sort="Boutin, Thibaud S" uniqKey="Boutin T" first="Thibaud S" last="Boutin">Thibaud S. Boutin</name><affiliation wicri:level="4"><nlm:aff id="A29">Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name><affiliation wicri:level="3"><nlm:aff id="A71">Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Stuttgart</region><settlement type="city">Stuttgart</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A72">University of Tübingen, Tübingen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A73">German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name><affiliation wicri:level="3"><nlm:aff id="A55">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A73">German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A74">Division of Preventive Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Preventive Oncology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Bruning, Thomas" sort="Bruning, Thomas" uniqKey="Bruning T" first="Thomas" last="Brüning">Thomas Brüning</name><affiliation wicri:level="1"><nlm:aff id="A75">Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum (IPA), Bochum, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum (IPA), Bochum</wicri:regionArea><wicri:noRegion>Bochum</wicri:noRegion><wicri:noRegion>Bochum</wicri:noRegion><wicri:noRegion>Bochum</wicri:noRegion></affiliation></author><author><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name><affiliation wicri:level="3"><nlm:aff id="A76">Division of Molecular Genetic Epidemiology, German Cancer Research Center, Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Molecular Genetic Epidemiology, German Cancer Research Center, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A77">Molecular Biology of Breast Cancer, Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Biology of Breast Cancer, Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Campbell, Archie" sort="Campbell, Archie" uniqKey="Campbell A" first="Archie" last="Campbell">Archie Campbell</name><affiliation wicri:level="4"><nlm:aff id="A78">Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><affiliation wicri:level="2"><nlm:aff id="A79">Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland</nlm:aff><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG</wicri:cityArea></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J." last="Chanock">Stephen J. Chanock</name><affiliation wicri:level="2"><nlm:aff id="A80">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Chapman, J Ross" sort="Chapman, J Ross" uniqKey="Chapman J" first="J. Ross" last="Chapman">J. Ross Chapman</name><affiliation wicri:level="4"><nlm:aff id="A81">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Chen, Yii Der Ida" sort="Chen, Yii Der Ida" uniqKey="Chen Y" first="Yii-Der Ida" last="Chen">Yii-Der Ida Chen</name><affiliation wicri:level="2"><nlm:aff id="A42">The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><affiliation wicri:level="1"><nlm:aff id="A82">Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name><affiliation wicri:level="2"><nlm:aff id="A83">Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Coviello, Andrea D" sort="Coviello, Andrea D" uniqKey="Coviello A" first="Andrea D." last="Coviello">Andrea D. Coviello</name><affiliation wicri:level="2"><nlm:aff id="A84">Boston University School of Medicine, Department of Medicine, Sections of Preventive Medicine and Endocrinology, Boston, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Boston University School of Medicine, Department of Medicine, Sections of Preventive Medicine and Endocrinology, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Cox, Angela" sort="Cox, Angela" uniqKey="Cox A" first="Angela" last="Cox">Angela Cox</name><affiliation wicri:level="1"><nlm:aff id="A85">Sheffield Cancer Research, Department of Oncology, University of Sheffield, Sheffield, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Sheffield Cancer Research, Department of Oncology, University of Sheffield, Sheffield</wicri:regionArea><wicri:noRegion>Sheffield</wicri:noRegion></affiliation></author><author><name sortKey="Czene, Kamila" sort="Czene, Kamila" uniqKey="Czene K" first="Kamila" last="Czene">Kamila Czene</name><affiliation wicri:level="1"><nlm:aff id="A86">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Darabi, Hatef" sort="Darabi, Hatef" uniqKey="Darabi H" first="Hatef" last="Darabi">Hatef Darabi</name><affiliation wicri:level="1"><nlm:aff id="A86">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="De Vivo, Immaculata" sort="De Vivo, Immaculata" uniqKey="De Vivo I" first="Immaculata" last="De Vivo">Immaculata De Vivo</name><affiliation wicri:level="2"><nlm:aff id="A12">Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A87">Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Demerath, Ellen W" sort="Demerath, Ellen W" uniqKey="Demerath E" first="Ellen W." last="Demerath">Ellen W. Demerath</name><affiliation wicri:level="2"><nlm:aff id="A88">Division of Epidemiology & Community Health, University of Minnesotta, Minneapolis MN 55455</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Division of Epidemiology & Community Health, University of Minnesotta</wicri:cityArea></affiliation></author><author><name sortKey="Dennis, Joe" sort="Dennis, Joe" uniqKey="Dennis J" first="Joe" last="Dennis">Joe Dennis</name><affiliation wicri:level="4"><nlm:aff id="A3">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Devilee, Peter" sort="Devilee, Peter" uniqKey="Devilee P" first="Peter" last="Devilee">Peter Devilee</name><affiliation wicri:level="1"><nlm:aff id="A89">Department of Human Genetics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Human Genetics, Leiden University Medical Center, 2300 RC Leiden</wicri:regionArea><wicri:noRegion>2300 RC Leiden</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A90">Department of Pathology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Pathology, Leiden University Medical Center, 2300 RC Leiden</wicri:regionArea><wicri:noRegion>2300 RC Leiden</wicri:noRegion></affiliation></author><author><name sortKey="Dork, Thilo" sort="Dork, Thilo" uniqKey="Dork T" first="Thilo" last="Dörk">Thilo Dörk</name><affiliation wicri:level="3"><nlm:aff id="A91">Gynaecology Research Unit, Hannover Medical School, Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Gynaecology Research Unit, Hannover Medical School, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Dos Santos Silva, Isabel" sort="Dos Santos Silva, Isabel" uniqKey="Dos Santos Silva I" first="Isabel" last="Dos-Santos-Silva">Isabel Dos-Santos-Silva</name><affiliation wicri:level="3"><nlm:aff id="A92">Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Dunning, Alison M" sort="Dunning, Alison M" uniqKey="Dunning A" first="Alison M." last="Dunning">Alison M. Dunning</name><affiliation wicri:level="4"><nlm:aff id="A93">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Eicher, John D" sort="Eicher, John D" uniqKey="Eicher J" first="John D." last="Eicher">John D. Eicher</name><affiliation wicri:level="1"><nlm:aff id="A5">NHLBI’s and Boston University’s Framingham Heart Study, Framingham, Massachusetts 01702-5827, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>NHLBI’s and Boston University’s Framingham Heart Study, Framingham, Massachusetts 01702-5827</wicri:regionArea><wicri:noRegion>Massachusetts 01702-5827</wicri:noRegion></affiliation></author><author><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A." last="Fasching">Peter A. Fasching</name><affiliation wicri:level="3"><nlm:aff id="A57">Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen</wicri:regionArea><placeName><settlement type="city">Erlangen</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Moyenne-Franconie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A94">David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Faul, Jessica D" sort="Faul, Jessica D" uniqKey="Faul J" first="Jessica D." last="Faul">Jessica D. Faul</name><affiliation wicri:level="2"><nlm:aff id="A95">Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Figueroa, Jonine" sort="Figueroa, Jonine" uniqKey="Figueroa J" first="Jonine" last="Figueroa">Jonine Figueroa</name><affiliation wicri:level="2"><nlm:aff id="A96">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Flesch Janys, Dieter" sort="Flesch Janys, Dieter" uniqKey="Flesch Janys D" first="Dieter" last="Flesch-Janys">Dieter Flesch-Janys</name><affiliation wicri:level="3"><nlm:aff id="A97">Department of Cancer Epidemiology/Clinical Cancer Registry, University Clinic Hamburg-Eppendorf, Hamburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Cancer Epidemiology/Clinical Cancer Registry, University Clinic Hamburg-Eppendorf, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A98">Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author><author><name sortKey="Gandin, Ilaria" sort="Gandin, Ilaria" uniqKey="Gandin I" first="Ilaria" last="Gandin">Ilaria Gandin</name><affiliation wicri:level="1"><nlm:aff id="A36">Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste</wicri:regionArea><wicri:noRegion>34137 Trieste</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A41">Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, 34149 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, 34149 Trieste</wicri:regionArea><wicri:noRegion>34149 Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Garcia, Melissa E" sort="Garcia, Melissa E" uniqKey="Garcia M" first="Melissa E." last="Garcia">Melissa E. Garcia</name><affiliation wicri:level="2"><nlm:aff id="A99">Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="García-Closas">Montserrat García-Closas</name><affiliation wicri:level="3"><nlm:aff id="A100">Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Genetics and Epidemiology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A101">Division of Cancer Studies, Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Studies, Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G." last="Giles">Graham G. Giles</name><affiliation wicri:level="4"><nlm:aff id="A102">Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A103">Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Girotto, Giorgia G" sort="Girotto, Giorgia G" uniqKey="Girotto G" first="Giorgia G." last="Girotto">Giorgia G. Girotto</name><affiliation wicri:level="1"><nlm:aff id="A41">Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, 34149 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, 34149 Trieste</wicri:regionArea><wicri:noRegion>34149 Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Goldberg, Mark S" sort="Goldberg, Mark S" uniqKey="Goldberg M" first="Mark S." last="Goldberg">Mark S. Goldberg</name><affiliation wicri:level="4"><nlm:aff id="A104">Department of Medicine, McGill University, Montreal, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Medicine, McGill University, Montreal</wicri:regionArea><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region><settlement type="city">Montréal</settlement></placeName><orgName type="university">Université McGill</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A105">Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University, Montreal, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University, Montreal</wicri:regionArea><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region><settlement type="city">Montréal</settlement></placeName><orgName type="university">Université McGill</orgName></affiliation></author><author><name sortKey="Gonzalez Neira, Anna" sort="Gonzalez Neira, Anna" uniqKey="Gonzalez Neira A" first="Anna" last="González-Neira">Anna González-Neira</name><affiliation wicri:level="3"><nlm:aff id="A59">Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Goodarzi, Mark O" sort="Goodarzi, Mark O" uniqKey="Goodarzi M" first="Mark O." last="Goodarzi">Mark O. Goodarzi</name><affiliation wicri:level="2"><nlm:aff id="A106">Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Grove, Megan L" sort="Grove, Megan L" uniqKey="Grove M" first="Megan L." last="Grove">Megan L. Grove</name><affiliation wicri:level="2"><nlm:aff id="A64">Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Gudbjartsson, Daniel F" sort="Gudbjartsson, Daniel F" uniqKey="Gudbjartsson D" first="Daniel F." last="Gudbjartsson">Daniel F. Gudbjartsson</name><affiliation wicri:level="1"><nlm:aff id="A14">deCODE genetics/Amgen, Inc., IS-101 Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE genetics/Amgen, Inc., IS-101 Reykjavik</wicri:regionArea><wicri:noRegion>IS-101 Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A107">School of Engineering and Natural Sciences, University of Iceland, IS-101 Reykjavik, Iceland,</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>School of Engineering and Natural Sciences, University of Iceland, IS-101 Reykjavik</wicri:regionArea><wicri:noRegion>IS-101 Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Guenel, Pascal" sort="Guenel, Pascal" uniqKey="Guenel P" first="Pascal" last="Guénel">Pascal Guénel</name><affiliation wicri:level="1"><nlm:aff id="A108">Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A109">University Paris-Sud, UMRS 1018, Villejuif, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>University Paris-Sud, UMRS 1018, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Guo, Xiuqing" sort="Guo, Xiuqing" uniqKey="Guo X" first="Xiuqing" last="Guo">Xiuqing Guo</name><affiliation wicri:level="2"><nlm:aff id="A42">The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Haiman, Christopher A" sort="Haiman, Christopher A" uniqKey="Haiman C" first="Christopher A." last="Haiman">Christopher A. Haiman</name><affiliation wicri:level="4"><nlm:aff id="A110">Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation wicri:level="1"><nlm:aff id="A86">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name><affiliation wicri:level="3"><nlm:aff id="A111">Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Henderson, Brian E" sort="Henderson, Brian E" uniqKey="Henderson B" first="Brian E." last="Henderson">Brian E. Henderson</name><affiliation wicri:level="4"><nlm:aff id="A110">Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Hocking, Lynne J" sort="Hocking, Lynne J" uniqKey="Hocking L" first="Lynne J." last="Hocking">Lynne J. Hocking</name><affiliation wicri:level="1"><nlm:aff id="A112">Musculoskeletal Research Programme, Division of Applied Medicine, University of Aberdeen, Aberdeen AB25 2ZD, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Musculoskeletal Research Programme, Division of Applied Medicine, University of Aberdeen, Aberdeen AB25 2ZD</wicri:regionArea><wicri:noRegion>Aberdeen AB25 2ZD</wicri:noRegion></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation wicri:level="3"><nlm:aff id="A43">Genetic Epidemiology Unit Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Genetic Epidemiology Unit Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Homuth, Georg" sort="Homuth, Georg" uniqKey="Homuth G" first="Georg" last="Homuth">Georg Homuth</name><affiliation wicri:level="1"><nlm:aff id="A113">Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 17475 Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Hooning, Maartje J" sort="Hooning, Maartje J" uniqKey="Hooning M" first="Maartje J." last="Hooning">Maartje J. Hooning</name><affiliation wicri:level="3"><nlm:aff id="A114">Department of Medical Oncology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Oncology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L." last="Hopper">John L. Hopper</name><affiliation wicri:level="4"><nlm:aff id="A102">Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Hu, Frank B" sort="Hu, Frank B" uniqKey="Hu F" first="Frank B." last="Hu">Frank B. Hu</name><affiliation wicri:level="2"><nlm:aff id="A12">Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A87">Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A115">Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Nutrition, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Huang, Jinyan" sort="Huang, Jinyan" uniqKey="Huang J" first="Jinyan" last="Huang">Jinyan Huang</name><affiliation wicri:level="1"><nlm:aff id="A116">State Key Laboratory of Medical Genomics,Shanghai Institute of Hematology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Medical Genomics,Shanghai Institute of Hematology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025</wicri:regionArea><wicri:noRegion>Shanghai 200025</wicri:noRegion></affiliation></author><author><name sortKey="Humphreys, Keith" sort="Humphreys, Keith" uniqKey="Humphreys K" first="Keith" last="Humphreys">Keith Humphreys</name><affiliation wicri:level="1"><nlm:aff id="A86">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J." last="Hunter">David J. Hunter</name><affiliation wicri:level="2"><nlm:aff id="A12">Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A20">Broad Institute of the Massachusetts Institute of Technology and Harvard University, 140 Cambridge 02142, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Broad Institute of the Massachusetts Institute of Technology and Harvard University, 140 Cambridge 02142, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A87">Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A115">Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Nutrition, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name><affiliation wicri:level="1"><nlm:aff id="A117">Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea><wicri:noRegion>Szczecin</wicri:noRegion></affiliation></author><author><name sortKey="Jones, Samuel E" sort="Jones, Samuel E" uniqKey="Jones S" first="Samuel E." last="Jones">Samuel E. Jones</name><affiliation wicri:level="1"><nlm:aff id="A2">Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW</wicri:regionArea><wicri:noRegion>EX2 5DW</wicri:noRegion></affiliation></author><author><name sortKey="Kabisch, Maria" sort="Kabisch, Maria" uniqKey="Kabisch M" first="Maria" last="Kabisch">Maria Kabisch</name><affiliation wicri:level="3"><nlm:aff id="A111">Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Karasik, David" sort="Karasik, David" uniqKey="Karasik D" first="David" last="Karasik">David Karasik</name><affiliation wicri:level="2"><nlm:aff id="A9">Harvard Medical School, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Harvard Medical School, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A118">Hebrew SeniorLife Institute for Aging Research, Boston, MA, 02131, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Hebrew SeniorLife Institute for Aging Research, Boston, MA, 02131</wicri:regionArea><wicri:noRegion>02131</wicri:noRegion></affiliation></author><author><name sortKey="Knight, Julia A" sort="Knight, Julia A" uniqKey="Knight J" first="Julia A." last="Knight">Julia A. Knight</name><affiliation wicri:level="1"><nlm:aff id="A119">Prosserman Centre for Health Research, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Prosserman Centre for Health Research, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A120">Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Kolcic, Ivana" sort="Kolcic, Ivana" uniqKey="Kolcic I" first="Ivana" last="Kolcic">Ivana Kolcic</name><affiliation wicri:level="1"><nlm:aff id="A121">Faculty of Medicine, University of Split, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Faculty of Medicine, University of Split, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Kooperberg, Charles" sort="Kooperberg, Charles" uniqKey="Kooperberg C" first="Charles" last="Kooperberg">Charles Kooperberg</name><affiliation wicri:level="2"><nlm:aff id="A37">Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Seattle, WA 98109-1024, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Seattle, WA 98109-1024</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Kosma, Veli Matti" sort="Kosma, Veli Matti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name><affiliation wicri:level="1"><nlm:aff id="A122">Cancer Center, Kuopio University Hospital, Kuopio, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Cancer Center, Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A123">School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A124">Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Kriebel, Jennifer" sort="Kriebel, Jennifer" uniqKey="Kriebel J" first="Jennifer" last="Kriebel">Jennifer Kriebel</name><affiliation wicri:level="1"><nlm:aff id="A24">Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A26">Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A125">German Center for Diabetes Research, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Center for Diabetes Research, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Kristensen, Vessela" sort="Kristensen, Vessela" uniqKey="Kristensen V" first="Vessela" last="Kristensen">Vessela Kristensen</name><affiliation wicri:level="3"><nlm:aff id="A69">Department of Genetics, Institute for Cancer Research, Radiumhospitalet, Oslo University Hospital, Oslo University Hospital, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Genetics, Institute for Cancer Research, Radiumhospitalet, Oslo University Hospital, Oslo University Hospital, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A70">Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A126">Department of Clinical Molecular Biology, Oslo University Hospital, University of Oslo, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Clinical Molecular Biology, Oslo University Hospital, University of Oslo, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Lambrechts, Diether" sort="Lambrechts, Diether" uniqKey="Lambrechts D" first="Diether" last="Lambrechts">Diether Lambrechts</name><affiliation wicri:level="1"><nlm:aff id="A127">Vesalius Research Center (VRC), VIB, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Vesalius Research Center (VRC), VIB, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A128">Laboratory for Translational Genetics, Department of Oncology, University of Leuven, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Laboratory for Translational Genetics, Department of Oncology, University of Leuven, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Langenberg, Claudia" sort="Langenberg, Claudia" uniqKey="Langenberg C" first="Claudia" last="Langenberg">Claudia Langenberg</name><affiliation wicri:level="1"><nlm:aff id="A1"> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ</wicri:regionArea><wicri:noRegion>CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Li, Jingmei" sort="Li, Jingmei" uniqKey="Li J" first="Jingmei" last="Li">Jingmei Li</name><affiliation wicri:level="1"><nlm:aff id="A86">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Li, Xin" sort="Li, Xin" uniqKey="Li X" first="Xin" last="Li">Xin Li</name><affiliation wicri:level="2"><nlm:aff id="A12">Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Lindstrom, Sara" sort="Lindstrom, Sara" uniqKey="Lindstrom S" first="Sara" last="Lindström">Sara Lindström</name><affiliation wicri:level="2"><nlm:aff id="A12">Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Liu, Yongmei" sort="Liu, Yongmei" uniqKey="Liu Y" first="Yongmei" last="Liu">Yongmei Liu</name><affiliation><nlm:aff id="A129">Center for Human Genetics, Division of Public Health Sciences, Wake Forest School of Medicine</nlm:aff><wicri:noCountry code="subfield">Wake Forest School of Medicine</wicri:noCountry></affiliation></author><author><name sortKey="Luan, Jian N" sort="Luan, Jian N" uniqKey="Luan J" first="Jian N" last="Luan">Jian N Luan</name><affiliation wicri:level="1"><nlm:aff id="A1"> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ</wicri:regionArea><wicri:noRegion>CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name><affiliation wicri:level="1"><nlm:aff id="A117">Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea><wicri:noRegion>Szczecin</wicri:noRegion></affiliation></author><author><name sortKey="M Gi, Reedik" sort="M Gi, Reedik" uniqKey="M Gi R" first="Reedik" last="M Gi">Reedik M Gi</name><affiliation wicri:level="1"><nlm:aff id="A6">Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu, 51010</wicri:regionArea><wicri:noRegion>51010</wicri:noRegion></affiliation></author><author><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name><affiliation wicri:level="1"><nlm:aff id="A122">Cancer Center, Kuopio University Hospital, Kuopio, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Cancer Center, Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A123">School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A124">Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Manz, Judith" sort="Manz, Judith" uniqKey="Manz J" first="Judith" last="Manz">Judith Manz</name><affiliation wicri:level="1"><nlm:aff id="A24">Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A26">Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Margolin, Sara" sort="Margolin, Sara" uniqKey="Margolin S" first="Sara" last="Margolin">Sara Margolin</name><affiliation wicri:level="1"><nlm:aff id="A130">Department of Oncology - Pathology, Karolinska Institutet, Stockholm 17177, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Oncology - Pathology, Karolinska Institutet, Stockholm 17177</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Marten, Jonathan" sort="Marten, Jonathan" uniqKey="Marten J" first="Jonathan" last="Marten">Jonathan Marten</name><affiliation wicri:level="4"><nlm:aff id="A29">Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G." last="Martin">Nicholas G. Martin</name><affiliation wicri:level="1"><nlm:aff id="A131">QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>QIMR Berghofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Masciullo, Corrado" sort="Masciullo, Corrado" uniqKey="Masciullo C" first="Corrado" last="Masciullo">Corrado Masciullo</name><affiliation wicri:level="1"><nlm:aff id="A40">Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano</wicri:regionArea><wicri:noRegion>20132 Milano</wicri:noRegion></affiliation></author><author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name><affiliation wicri:level="4"><nlm:aff id="A132">Division of Gynaecology and Obstetrics, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Gynaecology and Obstetrics, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Michailidou, Kyriaki" sort="Michailidou, Kyriaki" uniqKey="Michailidou K" first="Kyriaki" last="Michailidou">Kyriaki Michailidou</name><affiliation wicri:level="4"><nlm:aff id="A3">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Mihailov, Evelin" sort="Mihailov, Evelin" uniqKey="Mihailov E" first="Evelin" last="Mihailov">Evelin Mihailov</name><affiliation wicri:level="1"><nlm:aff id="A6">Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu, 51010</wicri:regionArea><wicri:noRegion>51010</wicri:noRegion></affiliation></author><author><name sortKey="Milani, Lili" sort="Milani, Lili" uniqKey="Milani L" first="Lili" last="Milani">Lili Milani</name><affiliation wicri:level="1"><nlm:aff id="A6">Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu, 51010</wicri:regionArea><wicri:noRegion>51010</wicri:noRegion></affiliation></author><author><name sortKey="Milne, Roger L" sort="Milne, Roger L" uniqKey="Milne R" first="Roger L." last="Milne">Roger L. Milne</name><affiliation wicri:level="4"><nlm:aff id="A102">Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A103">Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Muller Nurasyid, Martina" sort="Muller Nurasyid, Martina" uniqKey="Muller Nurasyid M" first="Martina" last="Müller-Nurasyid">Martina Müller-Nurasyid</name><affiliation wicri:level="1"><nlm:aff id="A25">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A133">Department of Medicine I, Ludwig-Maximilians-University Munich, 81377 Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Medicine I, Ludwig-Maximilians-University Munich, 81377 Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A134">DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Nalls, Michael" sort="Nalls, Michael" uniqKey="Nalls M" first="Michael" last="Nalls">Michael Nalls</name><affiliation wicri:level="2"><nlm:aff id="A135">Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Neale, Ben M" sort="Neale, Ben M" uniqKey="Neale B" first="Ben M." last="Neale">Ben M. Neale</name><affiliation wicri:level="1"><nlm:aff id="A15">Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142</wicri:regionArea><wicri:noRegion>Massachusetts 02142</wicri:noRegion></affiliation><affiliation wicri:level="2"><nlm:aff id="A16">Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A17">Medical and Population Genetics, Broad Institute, Cambridge, MA 02142, US</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical and Population Genetics, Broad Institute, Cambridge, MA 02142</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name><affiliation wicri:level="1"><nlm:aff id="A136">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Neven, Patrick" sort="Neven, Patrick" uniqKey="Neven P" first="Patrick" last="Neven">Patrick Neven</name><affiliation wicri:level="1"><nlm:aff id="A137">KULeuven (University of Leuven), Department of Oncology, Multidisciplinary Breast Center, University Hospitals Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>KULeuven (University of Leuven), Department of Oncology, Multidisciplinary Breast Center, University Hospitals Leuven</wicri:regionArea><wicri:noRegion>University Hospitals Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Newman, Anne B" sort="Newman, Anne B" uniqKey="Newman A" first="Anne B." last="Newman">Anne B. Newman</name><affiliation wicri:level="4"><nlm:aff id="A138">Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region><settlement type="city">Pittsburgh</settlement></placeName><orgName type="university">Université de Pittsburgh</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A139">Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region><settlement type="city">Pittsburgh</settlement></placeName><orgName type="university">Université de Pittsburgh</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A140">Department of Clinical and Translational Science, University of Pittsburgh, Pittsburgh, Pennsylvania, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Clinical and Translational Science, University of Pittsburgh, Pittsburgh, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region><settlement type="city">Pittsburgh</settlement></placeName><orgName type="university">Université de Pittsburgh</orgName></affiliation></author><author><name sortKey="Nordestgaard, B Rge G" sort="Nordestgaard, B Rge G" uniqKey="Nordestgaard B" first="B Rge G." last="Nordestgaard">B Rge G. Nordestgaard</name><affiliation wicri:level="3"><nlm:aff id="A67">Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A68">Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Olson, Janet E" sort="Olson, Janet E" uniqKey="Olson J" first="Janet E." last="Olson">Janet E. Olson</name><affiliation wicri:level="2"><nlm:aff id="A62">Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Padmanabhan, Sandosh" sort="Padmanabhan, Sandosh" uniqKey="Padmanabhan S" first="Sandosh" last="Padmanabhan">Sandosh Padmanabhan</name><affiliation wicri:level="4"><nlm:aff id="A141">British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA</wicri:regionArea><orgName type="university">Université de Glasgow</orgName><placeName><settlement type="city">Glasgow</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name><affiliation wicri:level="3"><nlm:aff id="A142">IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Peters, Ulrike" sort="Peters, Ulrike" uniqKey="Peters U" first="Ulrike" last="Peters">Ulrike Peters</name><affiliation wicri:level="2"><nlm:aff id="A37">Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Seattle, WA 98109-1024, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Seattle, WA 98109-1024</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Petersmann, Astrid" sort="Petersmann, Astrid" uniqKey="Petersmann A" first="Astrid" last="Petersmann">Astrid Petersmann</name><affiliation wicri:level="1"><nlm:aff id="A143">Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Peto, Julian" sort="Peto, Julian" uniqKey="Peto J" first="Julian" last="Peto">Julian Peto</name><affiliation wicri:level="3"><nlm:aff id="A92">Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name><affiliation wicri:level="4"><nlm:aff id="A3">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A93">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Pirastu, Nicola N" sort="Pirastu, Nicola N" uniqKey="Pirastu N" first="Nicola N." last="Pirastu">Nicola N. Pirastu</name><affiliation wicri:level="1"><nlm:aff id="A36">Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste</wicri:regionArea><wicri:noRegion>34137 Trieste</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A41">Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, 34149 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, 34149 Trieste</wicri:regionArea><wicri:noRegion>34149 Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Pirie, Ailith" sort="Pirie, Ailith" uniqKey="Pirie A" first="Ailith" last="Pirie">Ailith Pirie</name><affiliation wicri:level="4"><nlm:aff id="A3">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Pistis, Giorgio" sort="Pistis, Giorgio" uniqKey="Pistis G" first="Giorgio" last="Pistis">Giorgio Pistis</name><affiliation wicri:level="1"><nlm:aff id="A33">Institute of Genetics and Biomedical Research, National Research Council, Cagliari, 09042 Sardinia, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Genetics and Biomedical Research, National Research Council, Cagliari, 09042 Sardinia</wicri:regionArea><wicri:noRegion>09042 Sardinia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A34">University of Sassari, Department of Biomedical Sciences, Sassari, 07100 Sassari, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>University of Sassari, Department of Biomedical Sciences, Sassari, 07100 Sassari</wicri:regionArea><wicri:noRegion>07100 Sassari</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A35">Center for Statistical Genetics, Ann Arbor, University of Michigan, Michigan 48109-2029, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Ann Arbor, University of Michigan, Michigan 48109-2029</wicri:regionArea><wicri:noRegion>Michigan 48109-2029</wicri:noRegion></affiliation></author><author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polasek">Ozren Polasek</name><affiliation wicri:level="1"><nlm:aff id="A121">Faculty of Medicine, University of Split, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Faculty of Medicine, University of Split, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Porteous, David" sort="Porteous, David" uniqKey="Porteous D" first="David" last="Porteous">David Porteous</name><affiliation wicri:level="4"><nlm:aff id="A78">Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M." last="Psaty">Bruce M. Psaty</name><affiliation wicri:level="4"><nlm:aff id="A27">Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle Washington 98101 USA</nlm:aff><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A144">Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="A145">Group Health Research Institute, Group Health Cooperative, Seattle, Washington 98101, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Group Health Research Institute, Group Health Cooperative, Seattle, Washington 98101</wicri:regionArea><wicri:noRegion>Washington 98101</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A146">Department of Health Services, University of Washington, Seattle, Washington 98101, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Health Services, University of Washington, Seattle, Washington 98101</wicri:regionArea><orgName type="university">Université de Washington</orgName><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Pylk S, Katri" sort="Pylk S, Katri" uniqKey="Pylk S K" first="Katri" last="Pylk S">Katri Pylk S</name><affiliation wicri:level="1"><nlm:aff id="A147">Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Chemistry, University of Oulu, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Chemistry, University of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A148">Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre NordLab, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre NordLab, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name><affiliation wicri:level="3"><nlm:aff id="A149">Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Raffel, Leslie J" sort="Raffel, Leslie J" uniqKey="Raffel L" first="Leslie J." last="Raffel">Leslie J. Raffel</name><affiliation wicri:level="2"><nlm:aff id="A150">Medical Genetics Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical Genetics Research Institute, Cedars-Sinai Medical Center, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A151">UCLA Clinical & Translational Science Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>UCLA Clinical & Translational Science Institute, Cedars-Sinai Medical Center, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><affiliation wicri:level="1"><nlm:aff id="A10">Department of Internal Medicine, Erasmus MC, 3015GE Rotterdam, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus MC, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A11">Netherlands Consortium on Health Aging and National Genomics Initiative, 2300 RC Leiden, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherlands Consortium on Health Aging and National Genomics Initiative, 2300 RC Leiden</wicri:regionArea><wicri:noRegion>2300 RC Leiden</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A43">Genetic Epidemiology Unit Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Genetic Epidemiology Unit Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><affiliation wicri:level="2"><nlm:aff id="A79">Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland</nlm:aff><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG</wicri:cityArea></affiliation></author><author><name sortKey="Rudolph, Anja" sort="Rudolph, Anja" uniqKey="Rudolph A" first="Anja" last="Rudolph">Anja Rudolph</name><affiliation wicri:level="3"><nlm:aff id="A152">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Ruggiero, Daniela" sort="Ruggiero, Daniela" uniqKey="Ruggiero D" first="Daniela" last="Ruggiero">Daniela Ruggiero</name><affiliation wicri:level="1"><nlm:aff id="A32">Institute of Genetics and Biophysics - CNR, via Pietro Castellino 111, 80131, Naples, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Genetics and Biophysics - CNR, via Pietro Castellino 111, 80131, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Sala, Cinzia F" sort="Sala, Cinzia F" uniqKey="Sala C" first="Cinzia F." last="Sala">Cinzia F. Sala</name><affiliation wicri:level="1"><nlm:aff id="A40">Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano</wicri:regionArea><wicri:noRegion>20132 Milano</wicri:noRegion></affiliation></author><author><name sortKey="Sanna, Serena" sort="Sanna, Serena" uniqKey="Sanna S" first="Serena" last="Sanna">Serena Sanna</name><affiliation wicri:level="1"><nlm:aff id="A33">Institute of Genetics and Biomedical Research, National Research Council, Cagliari, 09042 Sardinia, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Genetics and Biomedical Research, National Research Council, Cagliari, 09042 Sardinia</wicri:regionArea><wicri:noRegion>09042 Sardinia</wicri:noRegion></affiliation></author><author><name sortKey="Sawyer, Elinor J" sort="Sawyer, Elinor J" uniqKey="Sawyer E" first="Elinor J." last="Sawyer">Elinor J. Sawyer</name><affiliation wicri:level="3"><nlm:aff id="A153">Research Oncology, Guy’s Hospital, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Research Oncology, Guy’s Hospital, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Schlessinger, David" sort="Schlessinger, David" uniqKey="Schlessinger D" first="David" last="Schlessinger">David Schlessinger</name><affiliation wicri:level="2"><nlm:aff id="A154">National Institute on Aging, Intramural Research Program, Baltimore, MD 20892, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute on Aging, Intramural Research Program, Baltimore, MD 20892</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Schmidt, Marjanka K" sort="Schmidt, Marjanka K" uniqKey="Schmidt M" first="Marjanka K." last="Schmidt">Marjanka K. Schmidt</name><affiliation wicri:level="3"><nlm:aff id="A155">Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Schmidt, Frank" sort="Schmidt, Frank" uniqKey="Schmidt F" first="Frank" last="Schmidt">Frank Schmidt</name><affiliation wicri:level="1"><nlm:aff id="A113">Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 17475 Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K." last="Schmutzler">Rita K. Schmutzler</name><affiliation wicri:level="1"><nlm:aff id="A156">Division of Molecular Gyneco-Oncology, Department of Gynaecology and Obstetrics, University Hospital of Cologne, Cologne, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Molecular Gyneco-Oncology, Department of Gynaecology and Obstetrics, University Hospital of Cologne, Cologne</wicri:regionArea><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A157">Center of Familial Breast and Ovarian Cancer, University Hospital of Cologne, Cologne, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center of Familial Breast and Ovarian Cancer, University Hospital of Cologne, Cologne</wicri:regionArea><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A158">Center for Integrated Oncology, University Hospital of Cologne, Cologne, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center for Integrated Oncology, University Hospital of Cologne, Cologne</wicri:regionArea><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author><author><name sortKey="Schoemaker, Minouk J" sort="Schoemaker, Minouk J" uniqKey="Schoemaker M" first="Minouk J." last="Schoemaker">Minouk J. Schoemaker</name><affiliation wicri:level="3"><nlm:aff id="A100">Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Genetics and Epidemiology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Scott, Robert A" sort="Scott, Robert A" uniqKey="Scott R" first="Robert A." last="Scott">Robert A. Scott</name><affiliation wicri:level="1"><nlm:aff id="A1"> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ</wicri:regionArea><wicri:noRegion>CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Seynaeve, Caroline M" sort="Seynaeve, Caroline M" uniqKey="Seynaeve C" first="Caroline M." last="Seynaeve">Caroline M. Seynaeve</name><affiliation wicri:level="3"><nlm:aff id="A114">Department of Medical Oncology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Oncology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Simard, Jacques" sort="Simard, Jacques" uniqKey="Simard J" first="Jacques" last="Simard">Jacques Simard</name><affiliation wicri:level="1"><nlm:aff id="A159">Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City</wicri:regionArea><wicri:noRegion>Québec City</wicri:noRegion></affiliation></author><author><name sortKey="Sorice, Rossella" sort="Sorice, Rossella" uniqKey="Sorice R" first="Rossella" last="Sorice">Rossella Sorice</name><affiliation wicri:level="1"><nlm:aff id="A32">Institute of Genetics and Biophysics - CNR, via Pietro Castellino 111, 80131, Naples, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Genetics and Biophysics - CNR, via Pietro Castellino 111, 80131, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C." last="Southey">Melissa C. Southey</name><affiliation wicri:level="4"><nlm:aff id="A160">Department of Pathology, The University of Melbourne, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Pathology, The University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Stockl, Doris" sort="Stockl, Doris" uniqKey="Stockl D" first="Doris" last="Stöckl">Doris Stöckl</name><affiliation wicri:level="1"><nlm:aff id="A26">Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Strauch, Konstantin" sort="Strauch, Konstantin" uniqKey="Strauch K" first="Konstantin" last="Strauch">Konstantin Strauch</name><affiliation wicri:level="1"><nlm:aff id="A25">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A161">Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, 81377 Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, 81377 Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Swerdlow, Anthony" sort="Swerdlow, Anthony" uniqKey="Swerdlow A" first="Anthony" last="Swerdlow">Anthony Swerdlow</name><affiliation wicri:level="3"><nlm:aff id="A100">Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Genetics and Epidemiology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A162">Division of Breast Cancer Research, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Breast Cancer Research, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Taylor, Kent D" sort="Taylor, Kent D" uniqKey="Taylor K" first="Kent D." last="Taylor">Kent D. Taylor</name><affiliation wicri:level="2"><nlm:aff id="A42">The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Thorsteinsdottir, Unnur" sort="Thorsteinsdottir, Unnur" uniqKey="Thorsteinsdottir U" first="Unnur" last="Thorsteinsdottir">Unnur Thorsteinsdottir</name><affiliation wicri:level="1"><nlm:aff id="A14">deCODE genetics/Amgen, Inc., IS-101 Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE genetics/Amgen, Inc., IS-101 Reykjavik</wicri:regionArea><wicri:noRegion>IS-101 Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A50">Faculty of Medicine, University of Iceland, IS-101 Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, IS-101 Reykjavik</wicri:regionArea><wicri:noRegion>IS-101 Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Toland, Amanda E" sort="Toland, Amanda E" uniqKey="Toland A" first="Amanda E." last="Toland">Amanda E. Toland</name><affiliation wicri:level="2"><nlm:aff id="A163">Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Tomlinson, Ian" sort="Tomlinson, Ian" uniqKey="Tomlinson I" first="Ian" last="Tomlinson">Ian Tomlinson</name><affiliation wicri:level="4"><nlm:aff id="A81">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="A164">NIHR Oxford Biomedical Research Centre, Churchill Hospital, OX3 7LE Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>NIHR Oxford Biomedical Research Centre, Churchill Hospital, OX3 7LE Oxford</wicri:regionArea><wicri:noRegion>OX3 7LE Oxford</wicri:noRegion></affiliation></author><author><name sortKey="Truong, Therese" sort="Truong, Therese" uniqKey="Truong T" first="Thérèse" last="Truong">Thérèse Truong</name><affiliation wicri:level="1"><nlm:aff id="A108">Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A109">University Paris-Sud, UMRS 1018, Villejuif, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>University Paris-Sud, UMRS 1018, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Tryggvadottir, Laufey" sort="Tryggvadottir, Laufey" uniqKey="Tryggvadottir L" first="Laufey" last="Tryggvadottir">Laufey Tryggvadottir</name><affiliation wicri:level="1"><nlm:aff id="A165">Icelandic Cancer Registry, Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Cancer Registry, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Turner, Stephen T" sort="Turner, Stephen T" uniqKey="Turner S" first="Stephen T." last="Turner">Stephen T. Turner</name><affiliation wicri:level="2"><nlm:aff id="A166">Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Vozzi, Diego" sort="Vozzi, Diego" uniqKey="Vozzi D" first="Diego" last="Vozzi">Diego Vozzi</name><affiliation wicri:level="1"><nlm:aff id="A36">Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste</wicri:regionArea><wicri:noRegion>34137 Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Qin" sort="Wang, Qin" uniqKey="Wang Q" first="Qin" last="Wang">Qin Wang</name><affiliation wicri:level="4"><nlm:aff id="A3">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Wellons, Melissa" sort="Wellons, Melissa" uniqKey="Wellons M" first="Melissa" last="Wellons">Melissa Wellons</name><affiliation wicri:level="1"><nlm:aff id="A167">Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, 37203, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, 37203</wicri:regionArea><wicri:noRegion>37203</wicri:noRegion></affiliation></author><author><name sortKey="Willemsen, Gonneke" sort="Willemsen, Gonneke" uniqKey="Willemsen G" first="Gonneke" last="Willemsen">Gonneke Willemsen</name><affiliation wicri:level="3"><nlm:aff id="A46">Department of Biological Psychology, VU University Amsterdam, van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, VU University Amsterdam, van der Boechorststraat 1, 1081 BT, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F." last="Wilson">James F. Wilson</name><affiliation wicri:level="4"><nlm:aff id="A29">Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A79">Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland</nlm:aff><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG</wicri:cityArea></affiliation></author><author><name sortKey="Winqvist, Robert" sort="Winqvist, Robert" uniqKey="Winqvist R" first="Robert" last="Winqvist">Robert Winqvist</name><affiliation wicri:level="1"><nlm:aff id="A147">Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Chemistry, University of Oulu, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Chemistry, University of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A148">Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre NordLab, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre NordLab, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Wolffenbuttel, Bruce B H R" sort="Wolffenbuttel, Bruce B H R" uniqKey="Wolffenbuttel B" first="Bruce B. H. R." last="Wolffenbuttel">Bruce B. H. R. Wolffenbuttel</name><affiliation wicri:level="4"><nlm:aff id="A168">Department of Endocrinology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Endocrinology, University of Groningen, University Medical Centre Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region><settlement type="city">Groningue (ville)</settlement></placeName><orgName type="university">Université de Groningue</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A169">LifeLines Cohort Study and Biobank, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>LifeLines Cohort Study and Biobank, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F." last="Wright">Alan F. Wright</name><affiliation wicri:level="4"><nlm:aff id="A29">Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Yannoukakos, Drakoulis" sort="Yannoukakos, Drakoulis" uniqKey="Yannoukakos D" first="Drakoulis" last="Yannoukakos">Drakoulis Yannoukakos</name><affiliation wicri:level="3"><nlm:aff id="A170">Molecular Diagnostics Laboratory, IRRP, National Centre for Scientific Research “Demokritos“, Athens, Greece</nlm:aff><country xml:lang="fr">Grèce</country><wicri:regionArea>Molecular Diagnostics Laboratory, IRRP, National Centre for Scientific Research “Demokritos“, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Zemunik, Tatijana" sort="Zemunik, Tatijana" uniqKey="Zemunik T" first="Tatijana" last="Zemunik">Tatijana Zemunik</name><affiliation wicri:level="1"><nlm:aff id="A121">Faculty of Medicine, University of Split, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Faculty of Medicine, University of Split, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name><affiliation wicri:level="2"><nlm:aff id="A58">Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Zygmunt, Marek" sort="Zygmunt, Marek" uniqKey="Zygmunt M" first="Marek" last="Zygmunt">Marek Zygmunt</name><affiliation wicri:level="1"><nlm:aff id="A171">Department of Obstetrics and Gynecology, University Medicine Greifswald, 17475 Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Bergmann, Sven" sort="Bergmann, Sven" uniqKey="Bergmann S" first="Sven" last="Bergmann">Sven Bergmann</name><affiliation wicri:level="1"><nlm:aff id="A44">Department of Medical Genetics, University of Lausanne, CH-1005 Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Medical Genetics, University of Lausanne, CH-1005 Lausanne</wicri:regionArea><wicri:noRegion>CH-1005 Lausanne</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A45">Swiss Institute of Bioinformatics, CH-1015, Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Swiss Institute of Bioinformatics, CH-1015, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I." last="Boomsma">Dorret I. Boomsma</name><affiliation wicri:level="3"><nlm:aff id="A46">Department of Biological Psychology, VU University Amsterdam, van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, VU University Amsterdam, van der Boechorststraat 1, 1081 BT, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Buring, Julie E" sort="Buring, Julie E" uniqKey="Buring J" first="Julie E." last="Buring">Julie E. Buring</name><affiliation wicri:level="2"><nlm:aff id="A8">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, MA 02215</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Division of Preventive Medicine, Brigham and Women’s Hospital, Boston</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A9">Harvard Medical School, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Harvard Medical School, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name><affiliation wicri:level="1"><nlm:aff id="A51">Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21224, United States of America</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21224</wicri:regionArea><wicri:noRegion>Maryland 21224</wicri:noRegion></affiliation></author><author><name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W." last="Montgomery">Grant W. Montgomery</name><affiliation wicri:level="1"><nlm:aff id="A131">QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>QIMR Berghofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation wicri:level="1"><nlm:aff id="A49">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A50">Faculty of Medicine, University of Iceland, IS-101 Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, IS-101 Reykjavik</wicri:regionArea><wicri:noRegion>IS-101 Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D." last="Spector">Tim D. Spector</name><affiliation wicri:level="1"><nlm:aff id="A47">Department of Twin Research and Genetic Epidemiology, King’s College London, London SE1 7EH, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London SE1 7EH</wicri:regionArea><wicri:noRegion>London SE1 7EH</wicri:noRegion></affiliation></author><author><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name><affiliation wicri:level="3"><nlm:aff id="A43">Genetic Epidemiology Unit Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Genetic Epidemiology Unit Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Alizadeh, Behrooz Z" sort="Alizadeh, Behrooz Z" uniqKey="Alizadeh B" first="Behrooz Z." last="Alizadeh">Behrooz Z. Alizadeh</name><affiliation wicri:level="4"><nlm:aff id="A172">Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region><settlement type="city">Groningue (ville)</settlement></placeName><orgName type="university">Université de Groningue</orgName></affiliation></author><author><name sortKey="Ciullo, Marina" sort="Ciullo, Marina" uniqKey="Ciullo M" first="Marina" last="Ciullo">Marina Ciullo</name><affiliation wicri:level="1"><nlm:aff id="A32">Institute of Genetics and Biophysics - CNR, via Pietro Castellino 111, 80131, Naples, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Genetics and Biophysics - CNR, via Pietro Castellino 111, 80131, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Crisponi, Laura" sort="Crisponi, Laura" uniqKey="Crisponi L" first="Laura" last="Crisponi">Laura Crisponi</name><affiliation wicri:level="1"><nlm:aff id="A33">Institute of Genetics and Biomedical Research, National Research Council, Cagliari, 09042 Sardinia, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Genetics and Biomedical Research, National Research Council, Cagliari, 09042 Sardinia</wicri:regionArea><wicri:noRegion>09042 Sardinia</wicri:noRegion></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name><affiliation wicri:level="4"><nlm:aff id="A3">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A93">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Gasparini, Paolo P" sort="Gasparini, Paolo P" uniqKey="Gasparini P" first="Paolo P." last="Gasparini">Paolo P. Gasparini</name><affiliation wicri:level="1"><nlm:aff id="A36">Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste</wicri:regionArea><wicri:noRegion>34137 Trieste</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A41">Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, 34149 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, 34149 Trieste</wicri:regionArea><wicri:noRegion>34149 Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation wicri:level="1"><nlm:aff id="A24">Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A25">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A26">Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B." last="Harris">Tamara B. Harris</name><affiliation wicri:level="2"><nlm:aff id="A99">Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name><affiliation wicri:level="4"><nlm:aff id="A29">Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Kardia, Sharon L R" sort="Kardia, Sharon L R" uniqKey="Kardia S" first="Sharon L. R." last="Kardia">Sharon L. R. Kardia</name><affiliation wicri:level="2"><nlm:aff id="A38">Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name><affiliation wicri:level="2"><nlm:aff id="A12">Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A173">Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Mcknight, Barbara" sort="Mcknight, Barbara" uniqKey="Mcknight B" first="Barbara" last="Mcknight">Barbara Mcknight</name><affiliation wicri:level="4"><nlm:aff id="A56">Department of Biostatistics, University of Washington, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, University of Washington, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Metspalu, Andres" sort="Metspalu, Andres" uniqKey="Metspalu A" first="Andres" last="Metspalu">Andres Metspalu</name><affiliation wicri:level="1"><nlm:aff id="A6">Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu, 51010</wicri:regionArea><wicri:noRegion>51010</wicri:noRegion></affiliation></author><author><name sortKey="Morrison, Alanna C" sort="Morrison, Alanna C" uniqKey="Morrison A" first="Alanna C." last="Morrison">Alanna C. Morrison</name><affiliation wicri:level="2"><nlm:aff id="A64">Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Reiner, Alex P" sort="Reiner, Alex P" uniqKey="Reiner A" first="Alex P." last="Reiner">Alex P. Reiner</name><affiliation wicri:level="2"><nlm:aff id="A37">Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Seattle, WA 98109-1024, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Seattle, WA 98109-1024</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A144">Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Ridker, Paul M" sort="Ridker, Paul M" uniqKey="Ridker P" first="Paul M." last="Ridker">Paul M. Ridker</name><affiliation wicri:level="2"><nlm:aff id="A8">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, MA 02215</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Division of Preventive Medicine, Brigham and Women’s Hospital, Boston</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A9">Harvard Medical School, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Harvard Medical School, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Rotter, Jerome I" sort="Rotter, Jerome I" uniqKey="Rotter J" first="Jerome I." last="Rotter">Jerome I. Rotter</name><affiliation wicri:level="2"><nlm:aff id="A42">The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Toniolo, Daniela" sort="Toniolo, Daniela" uniqKey="Toniolo D" first="Daniela" last="Toniolo">Daniela Toniolo</name><affiliation wicri:level="1"><nlm:aff id="A40">Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano</wicri:regionArea><wicri:noRegion>20132 Milano</wicri:noRegion></affiliation></author><author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G." last="Uitterlinden">André G. Uitterlinden</name><affiliation wicri:level="1"><nlm:aff id="A10">Department of Internal Medicine, Erasmus MC, 3015GE Rotterdam, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus MC, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A11">Netherlands Consortium on Health Aging and National Genomics Initiative, 2300 RC Leiden, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherlands Consortium on Health Aging and National Genomics Initiative, 2300 RC Leiden</wicri:regionArea><wicri:noRegion>2300 RC Leiden</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A43">Genetic Epidemiology Unit Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Genetic Epidemiology Unit Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Ulivi, Sheila" sort="Ulivi, Sheila" uniqKey="Ulivi S" first="Sheila" last="Ulivi">Sheila Ulivi</name><affiliation wicri:level="1"><nlm:aff id="A36">Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste</wicri:regionArea><wicri:noRegion>34137 Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Volzke, Henry" sort="Volzke, Henry" uniqKey="Volzke H" first="Henry" last="Völzke">Henry Völzke</name><affiliation wicri:level="1"><nlm:aff id="A39">Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J." last="Wareham">Nicholas J. Wareham</name><affiliation wicri:level="1"><nlm:aff id="A1"> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ</wicri:regionArea><wicri:noRegion>CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Weir, David R" sort="Weir, David R" uniqKey="Weir D" first="David R." last="Weir">David R. Weir</name><affiliation wicri:level="2"><nlm:aff id="A95">Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Yerges Armstrong, Laura M" sort="Yerges Armstrong, Laura M" uniqKey="Yerges Armstrong L" first="Laura M." last="Yerges-Armstrong">Laura M. Yerges-Armstrong</name><affiliation wicri:level="2"><nlm:aff id="A31">Program in Personalized Medicine, Division of Endocrinology, Diabetes and Nutrition - University of Maryland School of Medicine, USA. Baltimore, MD 21201</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Program in Personalized Medicine, Division of Endocrinology, Diabetes and Nutrition - University of Maryland School of Medicine, USA. Baltimore</wicri:cityArea></affiliation></author><author><name sortKey="Price, Alkes L" sort="Price, Alkes L" uniqKey="Price A" first="Alkes L." last="Price">Alkes L. Price</name><affiliation wicri:level="2"><nlm:aff id="A12">Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Stefansson, Kari" sort="Stefansson, Kari" uniqKey="Stefansson K" first="Kari" last="Stefansson">Kari Stefansson</name><affiliation wicri:level="1"><nlm:aff id="A14">deCODE genetics/Amgen, Inc., IS-101 Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE genetics/Amgen, Inc., IS-101 Reykjavik</wicri:regionArea><wicri:noRegion>IS-101 Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A50">Faculty of Medicine, University of Iceland, IS-101 Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, IS-101 Reykjavik</wicri:regionArea><wicri:noRegion>IS-101 Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Visser, Jenny A" sort="Visser, Jenny A" uniqKey="Visser J" first="Jenny A." last="Visser">Jenny A. Visser</name><affiliation wicri:level="1"><nlm:aff id="A10">Department of Internal Medicine, Erasmus MC, 3015GE Rotterdam, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus MC, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Ong, Ken K" sort="Ong, Ken K" uniqKey="Ong K" first="Ken K." last="Ong">Ken K. Ong</name><affiliation wicri:level="1"><nlm:aff id="A1"> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ</wicri:regionArea><wicri:noRegion>CB2 0QQ</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A176">Department of Paediatrics,University of Cambridge,Cambridge, CB2 0QQ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Paediatrics,University of Cambridge,Cambridge, CB2 0QQ</wicri:regionArea><wicri:noRegion>CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Chang Claude, Jenny" sort="Chang Claude, Jenny" uniqKey="Chang Claude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><affiliation wicri:level="3"><nlm:aff id="A152">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Murabito, Joanne M" sort="Murabito, Joanne M" uniqKey="Murabito J" first="Joanne M." last="Murabito">Joanne M. Murabito</name><affiliation wicri:level="1"><nlm:aff id="A5">NHLBI’s and Boston University’s Framingham Heart Study, Framingham, Massachusetts 01702-5827, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>NHLBI’s and Boston University’s Framingham Heart Study, Framingham, Massachusetts 01702-5827</wicri:regionArea><wicri:noRegion>Massachusetts 01702-5827</wicri:noRegion></affiliation><affiliation wicri:level="2"><nlm:aff id="A177">Boston University School of Medicine, Department of Medicine, Section of General Internal Medicine, Boston, MA 02118, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Boston University School of Medicine, Department of Medicine, Section of General Internal Medicine, Boston, MA 02118</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Perry, John R B" sort="Perry, John R B" uniqKey="Perry J" first="John R. B." last="Perry">John R. B. Perry</name><affiliation wicri:level="1"><nlm:aff id="A1"> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ</wicri:regionArea><wicri:noRegion>CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Murray, Anna" sort="Murray, Anna" uniqKey="Murray A" first="Anna" last="Murray">Anna Murray</name><affiliation wicri:level="1"><nlm:aff id="A2">Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW</wicri:regionArea><wicri:noRegion>EX2 5DW</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26414677</idno><idno type="pmc">4661791</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661791</idno><idno type="RBID">PMC:4661791</idno><idno type="doi">10.1038/ng.3412</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">002E43</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002E43</idno><idno type="wicri:Area/Pmc/Curation">002C93</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002C93</idno><idno type="wicri:Area/Pmc/Checkpoint">000E91</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000E91</idno><idno type="wicri:source">PubMed</idno><idno type="wicri:Area/PubMed/Corpus">002725</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002725</idno><idno type="wicri:Area/PubMed/Curation">002656</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002656</idno><idno type="wicri:Area/PubMed/Checkpoint">002656</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002656</idno><idno type="wicri:Area/Ncbi/Merge">002B31</idno><idno type="wicri:Area/Ncbi/Curation">002B31</idno><idno type="wicri:Area/Ncbi/Checkpoint">002B31</idno><idno type="wicri:doubleKey">1061-4036:2015:Day F:large:scale:genomic</idno><idno type="wicri:Area/Main/Merge">002B98</idno><idno type="wicri:Area/Main/Curation">002B98</idno><idno type="wicri:Area/Main/Exploration">002B98</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Large-scale genomic analyses link reproductive ageing to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair</title><author><name sortKey="Day, Felix R" sort="Day, Felix R" uniqKey="Day F" first="Felix R." last="Day">Felix R. Day</name><affiliation wicri:level="1"><nlm:aff id="A1"> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ</wicri:regionArea><wicri:noRegion>CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Ruth, Katherine S" sort="Ruth, Katherine S" uniqKey="Ruth K" first="Katherine S." last="Ruth">Katherine S. Ruth</name><affiliation wicri:level="1"><nlm:aff id="A2">Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW</wicri:regionArea><wicri:noRegion>EX2 5DW</wicri:noRegion></affiliation></author><author><name sortKey="Thompson, Deborah J" sort="Thompson, Deborah J" uniqKey="Thompson D" first="Deborah J." last="Thompson">Deborah J. Thompson</name><affiliation wicri:level="4"><nlm:aff id="A3">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Lunetta, Kathryn L" sort="Lunetta, Kathryn L" uniqKey="Lunetta K" first="Kathryn L." last="Lunetta">Kathryn L. Lunetta</name><affiliation wicri:level="1"><nlm:aff id="A4">Boston University School of Public Health, Department of Biostatistics. Boston, Massachusetts 02118, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Boston University School of Public Health, Department of Biostatistics. Boston, Massachusetts 02118</wicri:regionArea><wicri:noRegion>Massachusetts 02118</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A5">NHLBI’s and Boston University’s Framingham Heart Study, Framingham, Massachusetts 01702-5827, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>NHLBI’s and Boston University’s Framingham Heart Study, Framingham, Massachusetts 01702-5827</wicri:regionArea><wicri:noRegion>Massachusetts 01702-5827</wicri:noRegion></affiliation></author><author><name sortKey="Pervjakova, Natalia" sort="Pervjakova, Natalia" uniqKey="Pervjakova N" first="Natalia" last="Pervjakova">Natalia Pervjakova</name><affiliation wicri:level="1"><nlm:aff id="A6">Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu, 51010</wicri:regionArea><wicri:noRegion>51010</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A7">Institute of Molecular and Cell Biology, University of Tartu, Tartu 51010, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Institute of Molecular and Cell Biology, University of Tartu, Tartu 51010</wicri:regionArea><wicri:noRegion>Tartu 51010</wicri:noRegion></affiliation></author><author><name sortKey="Chasman, Daniel I" sort="Chasman, Daniel I" uniqKey="Chasman D" first="Daniel I." last="Chasman">Daniel I. Chasman</name><affiliation><nlm:aff id="A8">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, MA 02215</nlm:aff><wicri:noCountry code="subfield">MA 02215</wicri:noCountry></affiliation><affiliation wicri:level="2"><nlm:aff id="A9">Harvard Medical School, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Harvard Medical School, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Stolk, Lisette" sort="Stolk, Lisette" uniqKey="Stolk L" first="Lisette" last="Stolk">Lisette Stolk</name><affiliation wicri:level="1"><nlm:aff id="A10">Department of Internal Medicine, Erasmus MC, 3015GE Rotterdam, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus MC, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A11">Netherlands Consortium on Health Aging and National Genomics Initiative, 2300 RC Leiden, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherlands Consortium on Health Aging and National Genomics Initiative, 2300 RC Leiden</wicri:regionArea><wicri:noRegion>2300 RC Leiden</wicri:noRegion></affiliation></author><author><name sortKey="Finucane, Hilary K" sort="Finucane, Hilary K" uniqKey="Finucane H" first="Hilary K." last="Finucane">Hilary K. Finucane</name><affiliation wicri:level="2"><nlm:aff id="A12">Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A13">Department of Mathematics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139-4307, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Mathematics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139-4307</wicri:regionArea><wicri:noRegion>Massachusetts 02139-4307</wicri:noRegion></affiliation></author><author><name sortKey="Sulem, Patrick" sort="Sulem, Patrick" uniqKey="Sulem P" first="Patrick" last="Sulem">Patrick Sulem</name><affiliation wicri:level="1"><nlm:aff id="A14">deCODE genetics/Amgen, Inc., IS-101 Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE genetics/Amgen, Inc., IS-101 Reykjavik</wicri:regionArea><wicri:noRegion>IS-101 Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Bulik Sullivan, Brendan" sort="Bulik Sullivan, Brendan" uniqKey="Bulik Sullivan B" first="Brendan" last="Bulik-Sullivan">Brendan Bulik-Sullivan</name><affiliation wicri:level="1"><nlm:aff id="A15">Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142</wicri:regionArea><wicri:noRegion>Massachusetts 02142</wicri:noRegion></affiliation><affiliation wicri:level="2"><nlm:aff id="A16">Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A17">Medical and Population Genetics, Broad Institute, Cambridge, MA 02142, US</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical and Population Genetics, Broad Institute, Cambridge, MA 02142</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Esko, T Nu" sort="Esko, T Nu" uniqKey="Esko T" first="T Nu" last="Esko">T Nu Esko</name><affiliation wicri:level="1"><nlm:aff id="A6">Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu, 51010</wicri:regionArea><wicri:noRegion>51010</wicri:noRegion></affiliation><affiliation wicri:level="2"><nlm:aff id="A18">Division of Endocrinology, Boston Children’s Hospital, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Endocrinology, Boston Children’s Hospital, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A19">Department of Genetics, Harvard Medical School, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, Harvard Medical School, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A20">Broad Institute of the Massachusetts Institute of Technology and Harvard University, 140 Cambridge 02142, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Broad Institute of the Massachusetts Institute of Technology and Harvard University, 140 Cambridge 02142, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Johnson, Andrew D" sort="Johnson, Andrew D" uniqKey="Johnson A" first="Andrew D." last="Johnson">Andrew D. Johnson</name><affiliation wicri:level="1"><nlm:aff id="A5">NHLBI’s and Boston University’s Framingham Heart Study, Framingham, Massachusetts 01702-5827, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>NHLBI’s and Boston University’s Framingham Heart Study, Framingham, Massachusetts 01702-5827</wicri:regionArea><wicri:noRegion>Massachusetts 01702-5827</wicri:noRegion></affiliation></author><author><name sortKey="Elks, Cathy E" sort="Elks, Cathy E" uniqKey="Elks C" first="Cathy E." last="Elks">Cathy E. Elks</name><affiliation wicri:level="1"><nlm:aff id="A1"> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ</wicri:regionArea><wicri:noRegion>CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Franceschini, Nora" sort="Franceschini, Nora" uniqKey="Franceschini N" first="Nora" last="Franceschini">Nora Franceschini</name><affiliation wicri:level="2"><nlm:aff id="A21">Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27599, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27599</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="He, Chunyan" sort="He, Chunyan" uniqKey="He C" first="Chunyan" last="He">Chunyan He</name><affiliation wicri:level="2"><nlm:aff id="A22">Department of Epidemiology, Indiana University Richard M. Fairbanks School of Public Health, Indianapolis, IN 46202, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Indiana University Richard M. Fairbanks School of Public Health, Indianapolis, IN 46202</wicri:regionArea><placeName><region type="state">Indiana</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A23">Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, IN 46202, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, IN 46202</wicri:regionArea><placeName><region type="state">Indiana</region></placeName></affiliation></author><author><name sortKey="Altmaier, Elisabeth" sort="Altmaier, Elisabeth" uniqKey="Altmaier E" first="Elisabeth" last="Altmaier">Elisabeth Altmaier</name><affiliation wicri:level="1"><nlm:aff id="A24">Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A25">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A26">Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Brody, Jennifer A" sort="Brody, Jennifer A" uniqKey="Brody J" first="Jennifer A." last="Brody">Jennifer A. Brody</name><affiliation wicri:level="4"><nlm:aff id="A27">Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle Washington 98101 USA</nlm:aff><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Franke, Lude L" sort="Franke, Lude L" uniqKey="Franke L" first="Lude L." last="Franke">Lude L. Franke</name><affiliation wicri:level="4"><nlm:aff id="A28">Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region><settlement type="city">Groningue (ville)</settlement></placeName><orgName type="university">Université de Groningue</orgName></affiliation></author><author><name sortKey="Huffman, Jennifer E" sort="Huffman, Jennifer E" uniqKey="Huffman J" first="Jennifer E." last="Huffman">Jennifer E. Huffman</name><affiliation wicri:level="1"><nlm:aff id="A5">NHLBI’s and Boston University’s Framingham Heart Study, Framingham, Massachusetts 01702-5827, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>NHLBI’s and Boston University’s Framingham Heart Study, Framingham, Massachusetts 01702-5827</wicri:regionArea><wicri:noRegion>Massachusetts 01702-5827</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A29">Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Keller, Margaux F" sort="Keller, Margaux F" uniqKey="Keller M" first="Margaux F." last="Keller">Margaux F. Keller</name><affiliation wicri:level="2"><nlm:aff id="A30">Merck Pharmaceuticals, 33 Avenue Louis Pasteur, Boston, MA 02115, United States</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Merck Pharmaceuticals, 33 Avenue Louis Pasteur, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Mcardle, Patrick F" sort="Mcardle, Patrick F" uniqKey="Mcardle P" first="Patrick F." last="Mcardle">Patrick F. Mcardle</name><affiliation wicri:level="2"><nlm:aff id="A31">Program in Personalized Medicine, Division of Endocrinology, Diabetes and Nutrition - University of Maryland School of Medicine, USA. Baltimore, MD 21201</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Program in Personalized Medicine, Division of Endocrinology, Diabetes and Nutrition - University of Maryland School of Medicine, USA. Baltimore</wicri:cityArea></affiliation></author><author><name sortKey="Nutile, Teresa" sort="Nutile, Teresa" uniqKey="Nutile T" first="Teresa" last="Nutile">Teresa Nutile</name><affiliation wicri:level="1"><nlm:aff id="A32">Institute of Genetics and Biophysics - CNR, via Pietro Castellino 111, 80131, Naples, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Genetics and Biophysics - CNR, via Pietro Castellino 111, 80131, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Porcu, Eleonora" sort="Porcu, Eleonora" uniqKey="Porcu E" first="Eleonora" last="Porcu">Eleonora Porcu</name><affiliation wicri:level="1"><nlm:aff id="A33">Institute of Genetics and Biomedical Research, National Research Council, Cagliari, 09042 Sardinia, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Genetics and Biomedical Research, National Research Council, Cagliari, 09042 Sardinia</wicri:regionArea><wicri:noRegion>09042 Sardinia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A34">University of Sassari, Department of Biomedical Sciences, Sassari, 07100 Sassari, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>University of Sassari, Department of Biomedical Sciences, Sassari, 07100 Sassari</wicri:regionArea><wicri:noRegion>07100 Sassari</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A35">Center for Statistical Genetics, Ann Arbor, University of Michigan, Michigan 48109-2029, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Ann Arbor, University of Michigan, Michigan 48109-2029</wicri:regionArea><wicri:noRegion>Michigan 48109-2029</wicri:noRegion></affiliation></author><author><name sortKey="Robino, Antonietta" sort="Robino, Antonietta" uniqKey="Robino A" first="Antonietta" last="Robino">Antonietta Robino</name><affiliation wicri:level="1"><nlm:aff id="A36">Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste</wicri:regionArea><wicri:noRegion>34137 Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Rose, Lynda M" sort="Rose, Lynda M" uniqKey="Rose L" first="Lynda M." last="Rose">Lynda M. Rose</name><affiliation wicri:level="2"><nlm:aff id="A8">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, MA 02215</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Division of Preventive Medicine, Brigham and Women’s Hospital, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Schick, Ursula M" sort="Schick, Ursula M" uniqKey="Schick U" first="Ursula M." last="Schick">Ursula M. Schick</name><affiliation wicri:level="2"><nlm:aff id="A37">Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Seattle, WA 98109-1024, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Seattle, WA 98109-1024</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Smith, Jennifer A" sort="Smith, Jennifer A" uniqKey="Smith J" first="Jennifer A." last="Smith">Jennifer A. Smith</name><affiliation wicri:level="2"><nlm:aff id="A38">Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name><affiliation wicri:level="1"><nlm:aff id="A39">Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Traglia, Michela" sort="Traglia, Michela" uniqKey="Traglia M" first="Michela" last="Traglia">Michela Traglia</name><affiliation wicri:level="1"><nlm:aff id="A40">Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano</wicri:regionArea><wicri:noRegion>20132 Milano</wicri:noRegion></affiliation></author><author><name sortKey="Vuckovic, Dragana" sort="Vuckovic, Dragana" uniqKey="Vuckovic D" first="Dragana" last="Vuckovic">Dragana Vuckovic</name><affiliation wicri:level="1"><nlm:aff id="A36">Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste</wicri:regionArea><wicri:noRegion>34137 Trieste</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A41">Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, 34149 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, 34149 Trieste</wicri:regionArea><wicri:noRegion>34149 Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Yao, Jie" sort="Yao, Jie" uniqKey="Yao J" first="Jie" last="Yao">Jie Yao</name><affiliation wicri:level="2"><nlm:aff id="A42">The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Zhao, Wei" sort="Zhao, Wei" uniqKey="Zhao W" first="Wei" last="Zhao">Wei Zhao</name><affiliation wicri:level="2"><nlm:aff id="A38">Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Albrecht, Eva" sort="Albrecht, Eva" uniqKey="Albrecht E" first="Eva" last="Albrecht">Eva Albrecht</name><affiliation wicri:level="1"><nlm:aff id="A25">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Amin, Najaf" sort="Amin, Najaf" uniqKey="Amin N" first="Najaf" last="Amin">Najaf Amin</name><affiliation wicri:level="3"><nlm:aff id="A43">Genetic Epidemiology Unit Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Genetic Epidemiology Unit Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Corre, Tanguy" sort="Corre, Tanguy" uniqKey="Corre T" first="Tanguy" last="Corre">Tanguy Corre</name><affiliation wicri:level="1"><nlm:aff id="A44">Department of Medical Genetics, University of Lausanne, CH-1005 Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Medical Genetics, University of Lausanne, CH-1005 Lausanne</wicri:regionArea><wicri:noRegion>CH-1005 Lausanne</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A45">Swiss Institute of Bioinformatics, CH-1015, Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Swiss Institute of Bioinformatics, CH-1015, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Hottenga, Jouke Jan" sort="Hottenga, Jouke Jan" uniqKey="Hottenga J" first="Jouke-Jan" last="Hottenga">Jouke-Jan Hottenga</name><affiliation wicri:level="3"><nlm:aff id="A46">Department of Biological Psychology, VU University Amsterdam, van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, VU University Amsterdam, van der Boechorststraat 1, 1081 BT, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name><affiliation wicri:level="1"><nlm:aff id="A47">Department of Twin Research and Genetic Epidemiology, King’s College London, London SE1 7EH, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London SE1 7EH</wicri:regionArea><wicri:noRegion>London SE1 7EH</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A48">National Institute for Health Research (NIHR) Biomedical Research Centre at Guy’s and St. Thomas’ Foundation Trust, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>National Institute for Health Research (NIHR) Biomedical Research Centre at Guy’s and St. Thomas’ Foundation Trust, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Smith, Albert V" sort="Smith, Albert V" uniqKey="Smith A" first="Albert V." last="Smith">Albert V. Smith</name><affiliation wicri:level="1"><nlm:aff id="A49">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A50">Faculty of Medicine, University of Iceland, IS-101 Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, IS-101 Reykjavik</wicri:regionArea><wicri:noRegion>IS-101 Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Tanaka, Toshiko" sort="Tanaka, Toshiko" uniqKey="Tanaka T" first="Toshiko" last="Tanaka">Toshiko Tanaka</name><affiliation wicri:level="1"><nlm:aff id="A51">Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21224, United States of America</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21224</wicri:regionArea><wicri:noRegion>Maryland 21224</wicri:noRegion></affiliation></author><author><name sortKey="Abecasis, Goncalo" sort="Abecasis, Goncalo" uniqKey="Abecasis G" first="Goncalo" last="Abecasis">Goncalo Abecasis</name><affiliation wicri:level="1"><nlm:aff id="A35">Center for Statistical Genetics, Ann Arbor, University of Michigan, Michigan 48109-2029, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Ann Arbor, University of Michigan, Michigan 48109-2029</wicri:regionArea><wicri:noRegion>Michigan 48109-2029</wicri:noRegion></affiliation></author><author><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name><affiliation wicri:level="1"><nlm:aff id="A52">Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario M5G 1X5</wicri:regionArea><wicri:noRegion>Ontario M5G 1X5</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A53">Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Molecular Genetics, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Anton Culver, Hoda" sort="Anton Culver, Hoda" uniqKey="Anton Culver H" first="Hoda" last="Anton-Culver">Hoda Anton-Culver</name><affiliation wicri:level="2"><nlm:aff id="A54">Department of Epidemiology, University of California Irvine, Irvine, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of California Irvine, Irvine, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Antoniou, Antonis C" sort="Antoniou, Antonis C" uniqKey="Antoniou A" first="Antonis C." last="Antoniou">Antonis C. Antoniou</name><affiliation wicri:level="4"><nlm:aff id="A3">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Arndt, Volker" sort="Arndt, Volker" uniqKey="Arndt V" first="Volker" last="Arndt">Volker Arndt</name><affiliation wicri:level="3"><nlm:aff id="A55">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Arnold, Alice M" sort="Arnold, Alice M" uniqKey="Arnold A" first="Alice M." last="Arnold">Alice M. Arnold</name><affiliation wicri:level="4"><nlm:aff id="A56">Department of Biostatistics, University of Washington, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, University of Washington, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Barbieri, Caterina" sort="Barbieri, Caterina" uniqKey="Barbieri C" first="Caterina" last="Barbieri">Caterina Barbieri</name><affiliation wicri:level="1"><nlm:aff id="A36">Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste</wicri:regionArea><wicri:noRegion>34137 Trieste</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A40">Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano</wicri:regionArea><wicri:noRegion>20132 Milano</wicri:noRegion></affiliation></author><author><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W." last="Beckmann">Matthias W. Beckmann</name><affiliation wicri:level="3"><nlm:aff id="A57">Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen</wicri:regionArea><placeName><settlement type="city">Erlangen</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Moyenne-Franconie</region></placeName></affiliation></author><author><name sortKey="Beeghly Fadiel, Alicia" sort="Beeghly Fadiel, Alicia" uniqKey="Beeghly Fadiel A" first="Alicia" last="Beeghly-Fadiel">Alicia Beeghly-Fadiel</name><affiliation wicri:level="2"><nlm:aff id="A58">Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benitez">Javier Benitez</name><affiliation wicri:level="3"><nlm:aff id="A59">Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A60">Centro de Investigación en Red de Enfermedades Raras (CIBERER), Valencia, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Centro de Investigación en Red de Enfermedades Raras (CIBERER), Valencia</wicri:regionArea><wicri:noRegion>Valencia</wicri:noRegion></affiliation></author><author><name sortKey="Bernstein, Leslie" sort="Bernstein, Leslie" uniqKey="Bernstein L" first="Leslie" last="Bernstein">Leslie Bernstein</name><affiliation wicri:level="2"><nlm:aff id="A61">Beckman Research Institute of City of Hope, Duarte, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Beckman Research Institute of City of Hope, Duarte, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Bielinski, Suzette J" sort="Bielinski, Suzette J" uniqKey="Bielinski S" first="Suzette J." last="Bielinski">Suzette J. Bielinski</name><affiliation wicri:level="2"><nlm:aff id="A62">Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Blomqvist, Carl" sort="Blomqvist, Carl" uniqKey="Blomqvist C" first="Carl" last="Blomqvist">Carl Blomqvist</name><affiliation wicri:level="1"><nlm:aff id="A63">Department of Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Oncology, University of Helsinki and Helsinki University Central Hospital, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><affiliation wicri:level="2"><nlm:aff id="A64">Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A65">Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Bogdanova, Natalia V" sort="Bogdanova, Natalia V" uniqKey="Bogdanova N" first="Natalia V." last="Bogdanova">Natalia V. Bogdanova</name><affiliation wicri:level="3"><nlm:aff id="A66">Department of Radiation Oncology, Hannover Medical School, Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiation Oncology, Hannover Medical School, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Bojesen, Stig E" sort="Bojesen, Stig E" uniqKey="Bojesen S" first="Stig E." last="Bojesen">Stig E. Bojesen</name><affiliation wicri:level="3"><nlm:aff id="A67">Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A68">Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Bolla, Manjeet K" sort="Bolla, Manjeet K" uniqKey="Bolla M" first="Manjeet K." last="Bolla">Manjeet K. Bolla</name><affiliation wicri:level="4"><nlm:aff id="A3">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Borresen Dale, Anne Lise" sort="Borresen Dale, Anne Lise" uniqKey="Borresen Dale A" first="Anne-Lise" last="Borresen-Dale">Anne-Lise Borresen-Dale</name><affiliation wicri:level="3"><nlm:aff id="A69">Department of Genetics, Institute for Cancer Research, Radiumhospitalet, Oslo University Hospital, Oslo University Hospital, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Genetics, Institute for Cancer Research, Radiumhospitalet, Oslo University Hospital, Oslo University Hospital, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A70">Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Boutin, Thibaud S" sort="Boutin, Thibaud S" uniqKey="Boutin T" first="Thibaud S" last="Boutin">Thibaud S. Boutin</name><affiliation wicri:level="4"><nlm:aff id="A29">Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name><affiliation wicri:level="3"><nlm:aff id="A71">Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Stuttgart</region><settlement type="city">Stuttgart</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A72">University of Tübingen, Tübingen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A73">German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name><affiliation wicri:level="3"><nlm:aff id="A55">Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A73">German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A74">Division of Preventive Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Preventive Oncology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Bruning, Thomas" sort="Bruning, Thomas" uniqKey="Bruning T" first="Thomas" last="Brüning">Thomas Brüning</name><affiliation wicri:level="1"><nlm:aff id="A75">Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum (IPA), Bochum, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum (IPA), Bochum</wicri:regionArea><wicri:noRegion>Bochum</wicri:noRegion><wicri:noRegion>Bochum</wicri:noRegion><wicri:noRegion>Bochum</wicri:noRegion></affiliation></author><author><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name><affiliation wicri:level="3"><nlm:aff id="A76">Division of Molecular Genetic Epidemiology, German Cancer Research Center, Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Molecular Genetic Epidemiology, German Cancer Research Center, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A77">Molecular Biology of Breast Cancer, Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Biology of Breast Cancer, Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Campbell, Archie" sort="Campbell, Archie" uniqKey="Campbell A" first="Archie" last="Campbell">Archie Campbell</name><affiliation wicri:level="4"><nlm:aff id="A78">Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><affiliation wicri:level="2"><nlm:aff id="A79">Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland</nlm:aff><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG</wicri:cityArea></affiliation></author><author><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J." last="Chanock">Stephen J. Chanock</name><affiliation wicri:level="2"><nlm:aff id="A80">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Chapman, J Ross" sort="Chapman, J Ross" uniqKey="Chapman J" first="J. Ross" last="Chapman">J. Ross Chapman</name><affiliation wicri:level="4"><nlm:aff id="A81">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Chen, Yii Der Ida" sort="Chen, Yii Der Ida" uniqKey="Chen Y" first="Yii-Der Ida" last="Chen">Yii-Der Ida Chen</name><affiliation wicri:level="2"><nlm:aff id="A42">The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name><affiliation wicri:level="1"><nlm:aff id="A82">Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane</wicri:regionArea><wicri:noRegion>Brisbane</wicri:noRegion></affiliation></author><author><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name><affiliation wicri:level="2"><nlm:aff id="A83">Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Coviello, Andrea D" sort="Coviello, Andrea D" uniqKey="Coviello A" first="Andrea D." last="Coviello">Andrea D. Coviello</name><affiliation wicri:level="2"><nlm:aff id="A84">Boston University School of Medicine, Department of Medicine, Sections of Preventive Medicine and Endocrinology, Boston, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Boston University School of Medicine, Department of Medicine, Sections of Preventive Medicine and Endocrinology, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Cox, Angela" sort="Cox, Angela" uniqKey="Cox A" first="Angela" last="Cox">Angela Cox</name><affiliation wicri:level="1"><nlm:aff id="A85">Sheffield Cancer Research, Department of Oncology, University of Sheffield, Sheffield, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Sheffield Cancer Research, Department of Oncology, University of Sheffield, Sheffield</wicri:regionArea><wicri:noRegion>Sheffield</wicri:noRegion></affiliation></author><author><name sortKey="Czene, Kamila" sort="Czene, Kamila" uniqKey="Czene K" first="Kamila" last="Czene">Kamila Czene</name><affiliation wicri:level="1"><nlm:aff id="A86">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Darabi, Hatef" sort="Darabi, Hatef" uniqKey="Darabi H" first="Hatef" last="Darabi">Hatef Darabi</name><affiliation wicri:level="1"><nlm:aff id="A86">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="De Vivo, Immaculata" sort="De Vivo, Immaculata" uniqKey="De Vivo I" first="Immaculata" last="De Vivo">Immaculata De Vivo</name><affiliation wicri:level="2"><nlm:aff id="A12">Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A87">Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Demerath, Ellen W" sort="Demerath, Ellen W" uniqKey="Demerath E" first="Ellen W." last="Demerath">Ellen W. Demerath</name><affiliation wicri:level="2"><nlm:aff id="A88">Division of Epidemiology & Community Health, University of Minnesotta, Minneapolis MN 55455</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Division of Epidemiology & Community Health, University of Minnesotta</wicri:cityArea></affiliation></author><author><name sortKey="Dennis, Joe" sort="Dennis, Joe" uniqKey="Dennis J" first="Joe" last="Dennis">Joe Dennis</name><affiliation wicri:level="4"><nlm:aff id="A3">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Devilee, Peter" sort="Devilee, Peter" uniqKey="Devilee P" first="Peter" last="Devilee">Peter Devilee</name><affiliation wicri:level="1"><nlm:aff id="A89">Department of Human Genetics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Human Genetics, Leiden University Medical Center, 2300 RC Leiden</wicri:regionArea><wicri:noRegion>2300 RC Leiden</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A90">Department of Pathology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Pathology, Leiden University Medical Center, 2300 RC Leiden</wicri:regionArea><wicri:noRegion>2300 RC Leiden</wicri:noRegion></affiliation></author><author><name sortKey="Dork, Thilo" sort="Dork, Thilo" uniqKey="Dork T" first="Thilo" last="Dörk">Thilo Dörk</name><affiliation wicri:level="3"><nlm:aff id="A91">Gynaecology Research Unit, Hannover Medical School, Hannover, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Gynaecology Research Unit, Hannover Medical School, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Dos Santos Silva, Isabel" sort="Dos Santos Silva, Isabel" uniqKey="Dos Santos Silva I" first="Isabel" last="Dos-Santos-Silva">Isabel Dos-Santos-Silva</name><affiliation wicri:level="3"><nlm:aff id="A92">Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Dunning, Alison M" sort="Dunning, Alison M" uniqKey="Dunning A" first="Alison M." last="Dunning">Alison M. Dunning</name><affiliation wicri:level="4"><nlm:aff id="A93">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Eicher, John D" sort="Eicher, John D" uniqKey="Eicher J" first="John D." last="Eicher">John D. Eicher</name><affiliation wicri:level="1"><nlm:aff id="A5">NHLBI’s and Boston University’s Framingham Heart Study, Framingham, Massachusetts 01702-5827, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>NHLBI’s and Boston University’s Framingham Heart Study, Framingham, Massachusetts 01702-5827</wicri:regionArea><wicri:noRegion>Massachusetts 01702-5827</wicri:noRegion></affiliation></author><author><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A." last="Fasching">Peter A. Fasching</name><affiliation wicri:level="3"><nlm:aff id="A57">Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen</wicri:regionArea><placeName><settlement type="city">Erlangen</settlement><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Moyenne-Franconie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A94">David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, CA</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Faul, Jessica D" sort="Faul, Jessica D" uniqKey="Faul J" first="Jessica D." last="Faul">Jessica D. Faul</name><affiliation wicri:level="2"><nlm:aff id="A95">Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Figueroa, Jonine" sort="Figueroa, Jonine" uniqKey="Figueroa J" first="Jonine" last="Figueroa">Jonine Figueroa</name><affiliation wicri:level="2"><nlm:aff id="A96">Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Flesch Janys, Dieter" sort="Flesch Janys, Dieter" uniqKey="Flesch Janys D" first="Dieter" last="Flesch-Janys">Dieter Flesch-Janys</name><affiliation wicri:level="3"><nlm:aff id="A97">Department of Cancer Epidemiology/Clinical Cancer Registry, University Clinic Hamburg-Eppendorf, Hamburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Cancer Epidemiology/Clinical Cancer Registry, University Clinic Hamburg-Eppendorf, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A98">Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author><author><name sortKey="Gandin, Ilaria" sort="Gandin, Ilaria" uniqKey="Gandin I" first="Ilaria" last="Gandin">Ilaria Gandin</name><affiliation wicri:level="1"><nlm:aff id="A36">Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste</wicri:regionArea><wicri:noRegion>34137 Trieste</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A41">Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, 34149 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, 34149 Trieste</wicri:regionArea><wicri:noRegion>34149 Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Garcia, Melissa E" sort="Garcia, Melissa E" uniqKey="Garcia M" first="Melissa E." last="Garcia">Melissa E. Garcia</name><affiliation wicri:level="2"><nlm:aff id="A99">Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="García-Closas">Montserrat García-Closas</name><affiliation wicri:level="3"><nlm:aff id="A100">Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Genetics and Epidemiology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A101">Division of Cancer Studies, Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Cancer Studies, Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G." last="Giles">Graham G. Giles</name><affiliation wicri:level="4"><nlm:aff id="A102">Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A103">Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Girotto, Giorgia G" sort="Girotto, Giorgia G" uniqKey="Girotto G" first="Giorgia G." last="Girotto">Giorgia G. Girotto</name><affiliation wicri:level="1"><nlm:aff id="A41">Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, 34149 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, 34149 Trieste</wicri:regionArea><wicri:noRegion>34149 Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Goldberg, Mark S" sort="Goldberg, Mark S" uniqKey="Goldberg M" first="Mark S." last="Goldberg">Mark S. Goldberg</name><affiliation wicri:level="4"><nlm:aff id="A104">Department of Medicine, McGill University, Montreal, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Medicine, McGill University, Montreal</wicri:regionArea><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region><settlement type="city">Montréal</settlement></placeName><orgName type="university">Université McGill</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A105">Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University, Montreal, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University, Montreal</wicri:regionArea><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region><settlement type="city">Montréal</settlement></placeName><orgName type="university">Université McGill</orgName></affiliation></author><author><name sortKey="Gonzalez Neira, Anna" sort="Gonzalez Neira, Anna" uniqKey="Gonzalez Neira A" first="Anna" last="González-Neira">Anna González-Neira</name><affiliation wicri:level="3"><nlm:aff id="A59">Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Goodarzi, Mark O" sort="Goodarzi, Mark O" uniqKey="Goodarzi M" first="Mark O." last="Goodarzi">Mark O. Goodarzi</name><affiliation wicri:level="2"><nlm:aff id="A106">Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Grove, Megan L" sort="Grove, Megan L" uniqKey="Grove M" first="Megan L." last="Grove">Megan L. Grove</name><affiliation wicri:level="2"><nlm:aff id="A64">Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Gudbjartsson, Daniel F" sort="Gudbjartsson, Daniel F" uniqKey="Gudbjartsson D" first="Daniel F." last="Gudbjartsson">Daniel F. Gudbjartsson</name><affiliation wicri:level="1"><nlm:aff id="A14">deCODE genetics/Amgen, Inc., IS-101 Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE genetics/Amgen, Inc., IS-101 Reykjavik</wicri:regionArea><wicri:noRegion>IS-101 Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A107">School of Engineering and Natural Sciences, University of Iceland, IS-101 Reykjavik, Iceland,</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>School of Engineering and Natural Sciences, University of Iceland, IS-101 Reykjavik</wicri:regionArea><wicri:noRegion>IS-101 Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Guenel, Pascal" sort="Guenel, Pascal" uniqKey="Guenel P" first="Pascal" last="Guénel">Pascal Guénel</name><affiliation wicri:level="1"><nlm:aff id="A108">Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A109">University Paris-Sud, UMRS 1018, Villejuif, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>University Paris-Sud, UMRS 1018, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Guo, Xiuqing" sort="Guo, Xiuqing" uniqKey="Guo X" first="Xiuqing" last="Guo">Xiuqing Guo</name><affiliation wicri:level="2"><nlm:aff id="A42">The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Haiman, Christopher A" sort="Haiman, Christopher A" uniqKey="Haiman C" first="Christopher A." last="Haiman">Christopher A. Haiman</name><affiliation wicri:level="4"><nlm:aff id="A110">Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><affiliation wicri:level="1"><nlm:aff id="A86">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name><affiliation wicri:level="3"><nlm:aff id="A111">Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Henderson, Brian E" sort="Henderson, Brian E" uniqKey="Henderson B" first="Brian E." last="Henderson">Brian E. Henderson</name><affiliation wicri:level="4"><nlm:aff id="A110">Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Los Angeles</settlement></placeName><orgName type="university">Université de Californie du Sud</orgName></affiliation></author><author><name sortKey="Hocking, Lynne J" sort="Hocking, Lynne J" uniqKey="Hocking L" first="Lynne J." last="Hocking">Lynne J. Hocking</name><affiliation wicri:level="1"><nlm:aff id="A112">Musculoskeletal Research Programme, Division of Applied Medicine, University of Aberdeen, Aberdeen AB25 2ZD, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Musculoskeletal Research Programme, Division of Applied Medicine, University of Aberdeen, Aberdeen AB25 2ZD</wicri:regionArea><wicri:noRegion>Aberdeen AB25 2ZD</wicri:noRegion></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation wicri:level="3"><nlm:aff id="A43">Genetic Epidemiology Unit Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Genetic Epidemiology Unit Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Homuth, Georg" sort="Homuth, Georg" uniqKey="Homuth G" first="Georg" last="Homuth">Georg Homuth</name><affiliation wicri:level="1"><nlm:aff id="A113">Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 17475 Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Hooning, Maartje J" sort="Hooning, Maartje J" uniqKey="Hooning M" first="Maartje J." last="Hooning">Maartje J. Hooning</name><affiliation wicri:level="3"><nlm:aff id="A114">Department of Medical Oncology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Oncology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L." last="Hopper">John L. Hopper</name><affiliation wicri:level="4"><nlm:aff id="A102">Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Hu, Frank B" sort="Hu, Frank B" uniqKey="Hu F" first="Frank B." last="Hu">Frank B. Hu</name><affiliation wicri:level="2"><nlm:aff id="A12">Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A87">Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A115">Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Nutrition, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Huang, Jinyan" sort="Huang, Jinyan" uniqKey="Huang J" first="Jinyan" last="Huang">Jinyan Huang</name><affiliation wicri:level="1"><nlm:aff id="A116">State Key Laboratory of Medical Genomics,Shanghai Institute of Hematology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Medical Genomics,Shanghai Institute of Hematology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025</wicri:regionArea><wicri:noRegion>Shanghai 200025</wicri:noRegion></affiliation></author><author><name sortKey="Humphreys, Keith" sort="Humphreys, Keith" uniqKey="Humphreys K" first="Keith" last="Humphreys">Keith Humphreys</name><affiliation wicri:level="1"><nlm:aff id="A86">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Hunter, David J" sort="Hunter, David J" uniqKey="Hunter D" first="David J." last="Hunter">David J. Hunter</name><affiliation wicri:level="2"><nlm:aff id="A12">Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A20">Broad Institute of the Massachusetts Institute of Technology and Harvard University, 140 Cambridge 02142, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Broad Institute of the Massachusetts Institute of Technology and Harvard University, 140 Cambridge 02142, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A87">Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A115">Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Nutrition, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name><affiliation wicri:level="1"><nlm:aff id="A117">Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea><wicri:noRegion>Szczecin</wicri:noRegion></affiliation></author><author><name sortKey="Jones, Samuel E" sort="Jones, Samuel E" uniqKey="Jones S" first="Samuel E." last="Jones">Samuel E. Jones</name><affiliation wicri:level="1"><nlm:aff id="A2">Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW</wicri:regionArea><wicri:noRegion>EX2 5DW</wicri:noRegion></affiliation></author><author><name sortKey="Kabisch, Maria" sort="Kabisch, Maria" uniqKey="Kabisch M" first="Maria" last="Kabisch">Maria Kabisch</name><affiliation wicri:level="3"><nlm:aff id="A111">Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Karasik, David" sort="Karasik, David" uniqKey="Karasik D" first="David" last="Karasik">David Karasik</name><affiliation wicri:level="2"><nlm:aff id="A9">Harvard Medical School, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Harvard Medical School, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A118">Hebrew SeniorLife Institute for Aging Research, Boston, MA, 02131, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Hebrew SeniorLife Institute for Aging Research, Boston, MA, 02131</wicri:regionArea><wicri:noRegion>02131</wicri:noRegion></affiliation></author><author><name sortKey="Knight, Julia A" sort="Knight, Julia A" uniqKey="Knight J" first="Julia A." last="Knight">Julia A. Knight</name><affiliation wicri:level="1"><nlm:aff id="A119">Prosserman Centre for Health Research, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Prosserman Centre for Health Research, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto</wicri:regionArea><wicri:noRegion>Toronto</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A120">Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Kolcic, Ivana" sort="Kolcic, Ivana" uniqKey="Kolcic I" first="Ivana" last="Kolcic">Ivana Kolcic</name><affiliation wicri:level="1"><nlm:aff id="A121">Faculty of Medicine, University of Split, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Faculty of Medicine, University of Split, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Kooperberg, Charles" sort="Kooperberg, Charles" uniqKey="Kooperberg C" first="Charles" last="Kooperberg">Charles Kooperberg</name><affiliation wicri:level="2"><nlm:aff id="A37">Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Seattle, WA 98109-1024, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Seattle, WA 98109-1024</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Kosma, Veli Matti" sort="Kosma, Veli Matti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name><affiliation wicri:level="1"><nlm:aff id="A122">Cancer Center, Kuopio University Hospital, Kuopio, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Cancer Center, Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A123">School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A124">Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Kriebel, Jennifer" sort="Kriebel, Jennifer" uniqKey="Kriebel J" first="Jennifer" last="Kriebel">Jennifer Kriebel</name><affiliation wicri:level="1"><nlm:aff id="A24">Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A26">Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A125">German Center for Diabetes Research, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Center for Diabetes Research, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Kristensen, Vessela" sort="Kristensen, Vessela" uniqKey="Kristensen V" first="Vessela" last="Kristensen">Vessela Kristensen</name><affiliation wicri:level="3"><nlm:aff id="A69">Department of Genetics, Institute for Cancer Research, Radiumhospitalet, Oslo University Hospital, Oslo University Hospital, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Genetics, Institute for Cancer Research, Radiumhospitalet, Oslo University Hospital, Oslo University Hospital, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A70">Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A126">Department of Clinical Molecular Biology, Oslo University Hospital, University of Oslo, Oslo, Norway</nlm:aff><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Clinical Molecular Biology, Oslo University Hospital, University of Oslo, Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Lambrechts, Diether" sort="Lambrechts, Diether" uniqKey="Lambrechts D" first="Diether" last="Lambrechts">Diether Lambrechts</name><affiliation wicri:level="1"><nlm:aff id="A127">Vesalius Research Center (VRC), VIB, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Vesalius Research Center (VRC), VIB, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A128">Laboratory for Translational Genetics, Department of Oncology, University of Leuven, Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Laboratory for Translational Genetics, Department of Oncology, University of Leuven, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Langenberg, Claudia" sort="Langenberg, Claudia" uniqKey="Langenberg C" first="Claudia" last="Langenberg">Claudia Langenberg</name><affiliation wicri:level="1"><nlm:aff id="A1"> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ</wicri:regionArea><wicri:noRegion>CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Li, Jingmei" sort="Li, Jingmei" uniqKey="Li J" first="Jingmei" last="Li">Jingmei Li</name><affiliation wicri:level="1"><nlm:aff id="A86">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 17177 Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Li, Xin" sort="Li, Xin" uniqKey="Li X" first="Xin" last="Li">Xin Li</name><affiliation wicri:level="2"><nlm:aff id="A12">Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Lindstrom, Sara" sort="Lindstrom, Sara" uniqKey="Lindstrom S" first="Sara" last="Lindström">Sara Lindström</name><affiliation wicri:level="2"><nlm:aff id="A12">Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Liu, Yongmei" sort="Liu, Yongmei" uniqKey="Liu Y" first="Yongmei" last="Liu">Yongmei Liu</name><affiliation><nlm:aff id="A129">Center for Human Genetics, Division of Public Health Sciences, Wake Forest School of Medicine</nlm:aff><wicri:noCountry code="subfield">Wake Forest School of Medicine</wicri:noCountry></affiliation></author><author><name sortKey="Luan, Jian N" sort="Luan, Jian N" uniqKey="Luan J" first="Jian N" last="Luan">Jian N Luan</name><affiliation wicri:level="1"><nlm:aff id="A1"> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ</wicri:regionArea><wicri:noRegion>CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name><affiliation wicri:level="1"><nlm:aff id="A117">Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Genetics and Pathology, Pomeranian Medical University, Szczecin</wicri:regionArea><wicri:noRegion>Szczecin</wicri:noRegion></affiliation></author><author><name sortKey="M Gi, Reedik" sort="M Gi, Reedik" uniqKey="M Gi R" first="Reedik" last="M Gi">Reedik M Gi</name><affiliation wicri:level="1"><nlm:aff id="A6">Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu, 51010</wicri:regionArea><wicri:noRegion>51010</wicri:noRegion></affiliation></author><author><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name><affiliation wicri:level="1"><nlm:aff id="A122">Cancer Center, Kuopio University Hospital, Kuopio, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Cancer Center, Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A123">School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A124">Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Manz, Judith" sort="Manz, Judith" uniqKey="Manz J" first="Judith" last="Manz">Judith Manz</name><affiliation wicri:level="1"><nlm:aff id="A24">Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A26">Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Margolin, Sara" sort="Margolin, Sara" uniqKey="Margolin S" first="Sara" last="Margolin">Sara Margolin</name><affiliation wicri:level="1"><nlm:aff id="A130">Department of Oncology - Pathology, Karolinska Institutet, Stockholm 17177, Sweden</nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Oncology - Pathology, Karolinska Institutet, Stockholm 17177</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Marten, Jonathan" sort="Marten, Jonathan" uniqKey="Marten J" first="Jonathan" last="Marten">Jonathan Marten</name><affiliation wicri:level="4"><nlm:aff id="A29">Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G." last="Martin">Nicholas G. Martin</name><affiliation wicri:level="1"><nlm:aff id="A131">QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>QIMR Berghofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Masciullo, Corrado" sort="Masciullo, Corrado" uniqKey="Masciullo C" first="Corrado" last="Masciullo">Corrado Masciullo</name><affiliation wicri:level="1"><nlm:aff id="A40">Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano</wicri:regionArea><wicri:noRegion>20132 Milano</wicri:noRegion></affiliation></author><author><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name><affiliation wicri:level="4"><nlm:aff id="A132">Division of Gynaecology and Obstetrics, Technische Universität München, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Gynaecology and Obstetrics, Technische Universität München, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université technique de Munich</orgName></affiliation></author><author><name sortKey="Michailidou, Kyriaki" sort="Michailidou, Kyriaki" uniqKey="Michailidou K" first="Kyriaki" last="Michailidou">Kyriaki Michailidou</name><affiliation wicri:level="4"><nlm:aff id="A3">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Mihailov, Evelin" sort="Mihailov, Evelin" uniqKey="Mihailov E" first="Evelin" last="Mihailov">Evelin Mihailov</name><affiliation wicri:level="1"><nlm:aff id="A6">Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu, 51010</wicri:regionArea><wicri:noRegion>51010</wicri:noRegion></affiliation></author><author><name sortKey="Milani, Lili" sort="Milani, Lili" uniqKey="Milani L" first="Lili" last="Milani">Lili Milani</name><affiliation wicri:level="1"><nlm:aff id="A6">Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu, 51010</wicri:regionArea><wicri:noRegion>51010</wicri:noRegion></affiliation></author><author><name sortKey="Milne, Roger L" sort="Milne, Roger L" uniqKey="Milne R" first="Roger L." last="Milne">Roger L. Milne</name><affiliation wicri:level="4"><nlm:aff id="A102">Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A103">Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Muller Nurasyid, Martina" sort="Muller Nurasyid, Martina" uniqKey="Muller Nurasyid M" first="Martina" last="Müller-Nurasyid">Martina Müller-Nurasyid</name><affiliation wicri:level="1"><nlm:aff id="A25">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A133">Department of Medicine I, Ludwig-Maximilians-University Munich, 81377 Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Medicine I, Ludwig-Maximilians-University Munich, 81377 Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A134">DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Nalls, Michael" sort="Nalls, Michael" uniqKey="Nalls M" first="Michael" last="Nalls">Michael Nalls</name><affiliation wicri:level="2"><nlm:aff id="A135">Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Neale, Ben M" sort="Neale, Ben M" uniqKey="Neale B" first="Ben M." last="Neale">Ben M. Neale</name><affiliation wicri:level="1"><nlm:aff id="A15">Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142</wicri:regionArea><wicri:noRegion>Massachusetts 02142</wicri:noRegion></affiliation><affiliation wicri:level="2"><nlm:aff id="A16">Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A17">Medical and Population Genetics, Broad Institute, Cambridge, MA 02142, US</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical and Population Genetics, Broad Institute, Cambridge, MA 02142</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name><affiliation wicri:level="1"><nlm:aff id="A136">Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki</wicri:regionArea><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Neven, Patrick" sort="Neven, Patrick" uniqKey="Neven P" first="Patrick" last="Neven">Patrick Neven</name><affiliation wicri:level="1"><nlm:aff id="A137">KULeuven (University of Leuven), Department of Oncology, Multidisciplinary Breast Center, University Hospitals Leuven, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>KULeuven (University of Leuven), Department of Oncology, Multidisciplinary Breast Center, University Hospitals Leuven</wicri:regionArea><wicri:noRegion>University Hospitals Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Newman, Anne B" sort="Newman, Anne B" uniqKey="Newman A" first="Anne B." last="Newman">Anne B. Newman</name><affiliation wicri:level="4"><nlm:aff id="A138">Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region><settlement type="city">Pittsburgh</settlement></placeName><orgName type="university">Université de Pittsburgh</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A139">Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region><settlement type="city">Pittsburgh</settlement></placeName><orgName type="university">Université de Pittsburgh</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A140">Department of Clinical and Translational Science, University of Pittsburgh, Pittsburgh, Pennsylvania, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Clinical and Translational Science, University of Pittsburgh, Pittsburgh, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region><settlement type="city">Pittsburgh</settlement></placeName><orgName type="university">Université de Pittsburgh</orgName></affiliation></author><author><name sortKey="Nordestgaard, B Rge G" sort="Nordestgaard, B Rge G" uniqKey="Nordestgaard B" first="B Rge G." last="Nordestgaard">B Rge G. Nordestgaard</name><affiliation wicri:level="3"><nlm:aff id="A67">Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A68">Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark</nlm:aff><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen</wicri:regionArea><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Olson, Janet E" sort="Olson, Janet E" uniqKey="Olson J" first="Janet E." last="Olson">Janet E. Olson</name><affiliation wicri:level="2"><nlm:aff id="A62">Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Padmanabhan, Sandosh" sort="Padmanabhan, Sandosh" uniqKey="Padmanabhan S" first="Sandosh" last="Padmanabhan">Sandosh Padmanabhan</name><affiliation wicri:level="4"><nlm:aff id="A141">British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA</wicri:regionArea><orgName type="university">Université de Glasgow</orgName><placeName><settlement type="city">Glasgow</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name><affiliation wicri:level="3"><nlm:aff id="A142">IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Peters, Ulrike" sort="Peters, Ulrike" uniqKey="Peters U" first="Ulrike" last="Peters">Ulrike Peters</name><affiliation wicri:level="2"><nlm:aff id="A37">Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Seattle, WA 98109-1024, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Seattle, WA 98109-1024</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Petersmann, Astrid" sort="Petersmann, Astrid" uniqKey="Petersmann A" first="Astrid" last="Petersmann">Astrid Petersmann</name><affiliation wicri:level="1"><nlm:aff id="A143">Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Peto, Julian" sort="Peto, Julian" uniqKey="Peto J" first="Julian" last="Peto">Julian Peto</name><affiliation wicri:level="3"><nlm:aff id="A92">Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Non-communicable Disease Epidemiology Department, London School of Hygiene and Tropical Medicine, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name><affiliation wicri:level="4"><nlm:aff id="A3">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A93">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Pirastu, Nicola N" sort="Pirastu, Nicola N" uniqKey="Pirastu N" first="Nicola N." last="Pirastu">Nicola N. Pirastu</name><affiliation wicri:level="1"><nlm:aff id="A36">Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste</wicri:regionArea><wicri:noRegion>34137 Trieste</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A41">Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, 34149 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, 34149 Trieste</wicri:regionArea><wicri:noRegion>34149 Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Pirie, Ailith" sort="Pirie, Ailith" uniqKey="Pirie A" first="Ailith" last="Pirie">Ailith Pirie</name><affiliation wicri:level="4"><nlm:aff id="A3">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Pistis, Giorgio" sort="Pistis, Giorgio" uniqKey="Pistis G" first="Giorgio" last="Pistis">Giorgio Pistis</name><affiliation wicri:level="1"><nlm:aff id="A33">Institute of Genetics and Biomedical Research, National Research Council, Cagliari, 09042 Sardinia, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Genetics and Biomedical Research, National Research Council, Cagliari, 09042 Sardinia</wicri:regionArea><wicri:noRegion>09042 Sardinia</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A34">University of Sassari, Department of Biomedical Sciences, Sassari, 07100 Sassari, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>University of Sassari, Department of Biomedical Sciences, Sassari, 07100 Sassari</wicri:regionArea><wicri:noRegion>07100 Sassari</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A35">Center for Statistical Genetics, Ann Arbor, University of Michigan, Michigan 48109-2029, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Statistical Genetics, Ann Arbor, University of Michigan, Michigan 48109-2029</wicri:regionArea><wicri:noRegion>Michigan 48109-2029</wicri:noRegion></affiliation></author><author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polasek">Ozren Polasek</name><affiliation wicri:level="1"><nlm:aff id="A121">Faculty of Medicine, University of Split, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Faculty of Medicine, University of Split, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Porteous, David" sort="Porteous, David" uniqKey="Porteous D" first="David" last="Porteous">David Porteous</name><affiliation wicri:level="4"><nlm:aff id="A78">Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M." last="Psaty">Bruce M. Psaty</name><affiliation wicri:level="4"><nlm:aff id="A27">Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle Washington 98101 USA</nlm:aff><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A144">Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="A145">Group Health Research Institute, Group Health Cooperative, Seattle, Washington 98101, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Group Health Research Institute, Group Health Cooperative, Seattle, Washington 98101</wicri:regionArea><wicri:noRegion>Washington 98101</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A146">Department of Health Services, University of Washington, Seattle, Washington 98101, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Health Services, University of Washington, Seattle, Washington 98101</wicri:regionArea><orgName type="university">Université de Washington</orgName><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Pylk S, Katri" sort="Pylk S, Katri" uniqKey="Pylk S K" first="Katri" last="Pylk S">Katri Pylk S</name><affiliation wicri:level="1"><nlm:aff id="A147">Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Chemistry, University of Oulu, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Chemistry, University of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A148">Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre NordLab, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre NordLab, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name><affiliation wicri:level="3"><nlm:aff id="A149">Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Raffel, Leslie J" sort="Raffel, Leslie J" uniqKey="Raffel L" first="Leslie J." last="Raffel">Leslie J. Raffel</name><affiliation wicri:level="2"><nlm:aff id="A150">Medical Genetics Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Medical Genetics Research Institute, Cedars-Sinai Medical Center, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A151">UCLA Clinical & Translational Science Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>UCLA Clinical & Translational Science Institute, Cedars-Sinai Medical Center, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><affiliation wicri:level="1"><nlm:aff id="A10">Department of Internal Medicine, Erasmus MC, 3015GE Rotterdam, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus MC, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A11">Netherlands Consortium on Health Aging and National Genomics Initiative, 2300 RC Leiden, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherlands Consortium on Health Aging and National Genomics Initiative, 2300 RC Leiden</wicri:regionArea><wicri:noRegion>2300 RC Leiden</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A43">Genetic Epidemiology Unit Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Genetic Epidemiology Unit Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><affiliation wicri:level="2"><nlm:aff id="A79">Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland</nlm:aff><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG</wicri:cityArea></affiliation></author><author><name sortKey="Rudolph, Anja" sort="Rudolph, Anja" uniqKey="Rudolph A" first="Anja" last="Rudolph">Anja Rudolph</name><affiliation wicri:level="3"><nlm:aff id="A152">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Ruggiero, Daniela" sort="Ruggiero, Daniela" uniqKey="Ruggiero D" first="Daniela" last="Ruggiero">Daniela Ruggiero</name><affiliation wicri:level="1"><nlm:aff id="A32">Institute of Genetics and Biophysics - CNR, via Pietro Castellino 111, 80131, Naples, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Genetics and Biophysics - CNR, via Pietro Castellino 111, 80131, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Sala, Cinzia F" sort="Sala, Cinzia F" uniqKey="Sala C" first="Cinzia F." last="Sala">Cinzia F. Sala</name><affiliation wicri:level="1"><nlm:aff id="A40">Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano</wicri:regionArea><wicri:noRegion>20132 Milano</wicri:noRegion></affiliation></author><author><name sortKey="Sanna, Serena" sort="Sanna, Serena" uniqKey="Sanna S" first="Serena" last="Sanna">Serena Sanna</name><affiliation wicri:level="1"><nlm:aff id="A33">Institute of Genetics and Biomedical Research, National Research Council, Cagliari, 09042 Sardinia, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Genetics and Biomedical Research, National Research Council, Cagliari, 09042 Sardinia</wicri:regionArea><wicri:noRegion>09042 Sardinia</wicri:noRegion></affiliation></author><author><name sortKey="Sawyer, Elinor J" sort="Sawyer, Elinor J" uniqKey="Sawyer E" first="Elinor J." last="Sawyer">Elinor J. Sawyer</name><affiliation wicri:level="3"><nlm:aff id="A153">Research Oncology, Guy’s Hospital, King’s College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Research Oncology, Guy’s Hospital, King’s College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Schlessinger, David" sort="Schlessinger, David" uniqKey="Schlessinger D" first="David" last="Schlessinger">David Schlessinger</name><affiliation wicri:level="2"><nlm:aff id="A154">National Institute on Aging, Intramural Research Program, Baltimore, MD 20892, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>National Institute on Aging, Intramural Research Program, Baltimore, MD 20892</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Schmidt, Marjanka K" sort="Schmidt, Marjanka K" uniqKey="Schmidt M" first="Marjanka K." last="Schmidt">Marjanka K. Schmidt</name><affiliation wicri:level="3"><nlm:aff id="A155">Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Netherlands Cancer Institute, Antoni van Leeuwenhoek hospital, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Schmidt, Frank" sort="Schmidt, Frank" uniqKey="Schmidt F" first="Frank" last="Schmidt">Frank Schmidt</name><affiliation wicri:level="1"><nlm:aff id="A113">Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 17475 Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K." last="Schmutzler">Rita K. Schmutzler</name><affiliation wicri:level="1"><nlm:aff id="A156">Division of Molecular Gyneco-Oncology, Department of Gynaecology and Obstetrics, University Hospital of Cologne, Cologne, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Molecular Gyneco-Oncology, Department of Gynaecology and Obstetrics, University Hospital of Cologne, Cologne</wicri:regionArea><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A157">Center of Familial Breast and Ovarian Cancer, University Hospital of Cologne, Cologne, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center of Familial Breast and Ovarian Cancer, University Hospital of Cologne, Cologne</wicri:regionArea><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A158">Center for Integrated Oncology, University Hospital of Cologne, Cologne, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Center for Integrated Oncology, University Hospital of Cologne, Cologne</wicri:regionArea><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion><wicri:noRegion>Cologne</wicri:noRegion></affiliation></author><author><name sortKey="Schoemaker, Minouk J" sort="Schoemaker, Minouk J" uniqKey="Schoemaker M" first="Minouk J." last="Schoemaker">Minouk J. Schoemaker</name><affiliation wicri:level="3"><nlm:aff id="A100">Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Genetics and Epidemiology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Scott, Robert A" sort="Scott, Robert A" uniqKey="Scott R" first="Robert A." last="Scott">Robert A. Scott</name><affiliation wicri:level="1"><nlm:aff id="A1"> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ</wicri:regionArea><wicri:noRegion>CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Seynaeve, Caroline M" sort="Seynaeve, Caroline M" uniqKey="Seynaeve C" first="Caroline M." last="Seynaeve">Caroline M. Seynaeve</name><affiliation wicri:level="3"><nlm:aff id="A114">Department of Medical Oncology, Erasmus University Medical Center, Rotterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Oncology, Erasmus University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Simard, Jacques" sort="Simard, Jacques" uniqKey="Simard J" first="Jacques" last="Simard">Jacques Simard</name><affiliation wicri:level="1"><nlm:aff id="A159">Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Centre Hospitalier Universitaire de Québec Research Center, Laval University, Québec City</wicri:regionArea><wicri:noRegion>Québec City</wicri:noRegion></affiliation></author><author><name sortKey="Sorice, Rossella" sort="Sorice, Rossella" uniqKey="Sorice R" first="Rossella" last="Sorice">Rossella Sorice</name><affiliation wicri:level="1"><nlm:aff id="A32">Institute of Genetics and Biophysics - CNR, via Pietro Castellino 111, 80131, Naples, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Genetics and Biophysics - CNR, via Pietro Castellino 111, 80131, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C." last="Southey">Melissa C. Southey</name><affiliation wicri:level="4"><nlm:aff id="A160">Department of Pathology, The University of Melbourne, Melbourne, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Pathology, The University of Melbourne, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Stockl, Doris" sort="Stockl, Doris" uniqKey="Stockl D" first="Doris" last="Stöckl">Doris Stöckl</name><affiliation wicri:level="1"><nlm:aff id="A26">Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Strauch, Konstantin" sort="Strauch, Konstantin" uniqKey="Strauch K" first="Konstantin" last="Strauch">Konstantin Strauch</name><affiliation wicri:level="1"><nlm:aff id="A25">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A161">Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, 81377 Munich, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, 81377 Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement></placeName></affiliation></author><author><name sortKey="Swerdlow, Anthony" sort="Swerdlow, Anthony" uniqKey="Swerdlow A" first="Anthony" last="Swerdlow">Anthony Swerdlow</name><affiliation wicri:level="3"><nlm:aff id="A100">Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Genetics and Epidemiology, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A162">Division of Breast Cancer Research, The Institute of Cancer Research, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Division of Breast Cancer Research, The Institute of Cancer Research, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Taylor, Kent D" sort="Taylor, Kent D" uniqKey="Taylor K" first="Kent D." last="Taylor">Kent D. Taylor</name><affiliation wicri:level="2"><nlm:aff id="A42">The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Thorsteinsdottir, Unnur" sort="Thorsteinsdottir, Unnur" uniqKey="Thorsteinsdottir U" first="Unnur" last="Thorsteinsdottir">Unnur Thorsteinsdottir</name><affiliation wicri:level="1"><nlm:aff id="A14">deCODE genetics/Amgen, Inc., IS-101 Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE genetics/Amgen, Inc., IS-101 Reykjavik</wicri:regionArea><wicri:noRegion>IS-101 Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A50">Faculty of Medicine, University of Iceland, IS-101 Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, IS-101 Reykjavik</wicri:regionArea><wicri:noRegion>IS-101 Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Toland, Amanda E" sort="Toland, Amanda E" uniqKey="Toland A" first="Amanda E." last="Toland">Amanda E. Toland</name><affiliation wicri:level="2"><nlm:aff id="A163">Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Tomlinson, Ian" sort="Tomlinson, Ian" uniqKey="Tomlinson I" first="Ian" last="Tomlinson">Ian Tomlinson</name><affiliation wicri:level="4"><nlm:aff id="A81">Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation><affiliation wicri:level="1"><nlm:aff id="A164">NIHR Oxford Biomedical Research Centre, Churchill Hospital, OX3 7LE Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>NIHR Oxford Biomedical Research Centre, Churchill Hospital, OX3 7LE Oxford</wicri:regionArea><wicri:noRegion>OX3 7LE Oxford</wicri:noRegion></affiliation></author><author><name sortKey="Truong, Therese" sort="Truong, Therese" uniqKey="Truong T" first="Thérèse" last="Truong">Thérèse Truong</name><affiliation wicri:level="1"><nlm:aff id="A108">Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Environmental Epidemiology of Cancer, Center for Research in Epidemiology and Population Health, INSERM, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A109">University Paris-Sud, UMRS 1018, Villejuif, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>University Paris-Sud, UMRS 1018, Villejuif</wicri:regionArea><wicri:noRegion>Villejuif</wicri:noRegion><wicri:noRegion>Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Tryggvadottir, Laufey" sort="Tryggvadottir, Laufey" uniqKey="Tryggvadottir L" first="Laufey" last="Tryggvadottir">Laufey Tryggvadottir</name><affiliation wicri:level="1"><nlm:aff id="A165">Icelandic Cancer Registry, Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Cancer Registry, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Turner, Stephen T" sort="Turner, Stephen T" uniqKey="Turner S" first="Stephen T." last="Turner">Stephen T. Turner</name><affiliation wicri:level="2"><nlm:aff id="A166">Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Vozzi, Diego" sort="Vozzi, Diego" uniqKey="Vozzi D" first="Diego" last="Vozzi">Diego Vozzi</name><affiliation wicri:level="1"><nlm:aff id="A36">Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste</wicri:regionArea><wicri:noRegion>34137 Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Qin" sort="Wang, Qin" uniqKey="Wang Q" first="Qin" last="Wang">Qin Wang</name><affiliation wicri:level="4"><nlm:aff id="A3">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Wellons, Melissa" sort="Wellons, Melissa" uniqKey="Wellons M" first="Melissa" last="Wellons">Melissa Wellons</name><affiliation wicri:level="1"><nlm:aff id="A167">Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, 37203, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, 37203</wicri:regionArea><wicri:noRegion>37203</wicri:noRegion></affiliation></author><author><name sortKey="Willemsen, Gonneke" sort="Willemsen, Gonneke" uniqKey="Willemsen G" first="Gonneke" last="Willemsen">Gonneke Willemsen</name><affiliation wicri:level="3"><nlm:aff id="A46">Department of Biological Psychology, VU University Amsterdam, van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, VU University Amsterdam, van der Boechorststraat 1, 1081 BT, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F." last="Wilson">James F. Wilson</name><affiliation wicri:level="4"><nlm:aff id="A29">Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A79">Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland</nlm:aff><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG</wicri:cityArea></affiliation></author><author><name sortKey="Winqvist, Robert" sort="Winqvist, Robert" uniqKey="Winqvist R" first="Robert" last="Winqvist">Robert Winqvist</name><affiliation wicri:level="1"><nlm:aff id="A147">Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Chemistry, University of Oulu, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Chemistry, University of Oulu, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A148">Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre NordLab, Oulu, Finland</nlm:aff><country xml:lang="fr">Finlande</country><wicri:regionArea>Laboratory of Cancer Genetics and Tumor Biology, Northern Finland Laboratory Centre NordLab, Oulu</wicri:regionArea><wicri:noRegion>Oulu</wicri:noRegion></affiliation></author><author><name sortKey="Wolffenbuttel, Bruce B H R" sort="Wolffenbuttel, Bruce B H R" uniqKey="Wolffenbuttel B" first="Bruce B. H. R." last="Wolffenbuttel">Bruce B. H. R. Wolffenbuttel</name><affiliation wicri:level="4"><nlm:aff id="A168">Department of Endocrinology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Endocrinology, University of Groningen, University Medical Centre Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region><settlement type="city">Groningue (ville)</settlement></placeName><orgName type="university">Université de Groningue</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A169">LifeLines Cohort Study and Biobank, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>LifeLines Cohort Study and Biobank, University Medical Center Groningen, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region></placeName></affiliation></author><author><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F." last="Wright">Alan F. Wright</name><affiliation wicri:level="4"><nlm:aff id="A29">Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Yannoukakos, Drakoulis" sort="Yannoukakos, Drakoulis" uniqKey="Yannoukakos D" first="Drakoulis" last="Yannoukakos">Drakoulis Yannoukakos</name><affiliation wicri:level="3"><nlm:aff id="A170">Molecular Diagnostics Laboratory, IRRP, National Centre for Scientific Research “Demokritos“, Athens, Greece</nlm:aff><country xml:lang="fr">Grèce</country><wicri:regionArea>Molecular Diagnostics Laboratory, IRRP, National Centre for Scientific Research “Demokritos“, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Zemunik, Tatijana" sort="Zemunik, Tatijana" uniqKey="Zemunik T" first="Tatijana" last="Zemunik">Tatijana Zemunik</name><affiliation wicri:level="1"><nlm:aff id="A121">Faculty of Medicine, University of Split, Split, Croatia</nlm:aff><country xml:lang="fr">Croatie</country><wicri:regionArea>Faculty of Medicine, University of Split, Split</wicri:regionArea><wicri:noRegion>Split</wicri:noRegion></affiliation></author><author><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name><affiliation wicri:level="2"><nlm:aff id="A58">Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Zygmunt, Marek" sort="Zygmunt, Marek" uniqKey="Zygmunt M" first="Marek" last="Zygmunt">Marek Zygmunt</name><affiliation wicri:level="1"><nlm:aff id="A171">Department of Obstetrics and Gynecology, University Medicine Greifswald, 17475 Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Obstetrics and Gynecology, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Bergmann, Sven" sort="Bergmann, Sven" uniqKey="Bergmann S" first="Sven" last="Bergmann">Sven Bergmann</name><affiliation wicri:level="1"><nlm:aff id="A44">Department of Medical Genetics, University of Lausanne, CH-1005 Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Medical Genetics, University of Lausanne, CH-1005 Lausanne</wicri:regionArea><wicri:noRegion>CH-1005 Lausanne</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A45">Swiss Institute of Bioinformatics, CH-1015, Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Swiss Institute of Bioinformatics, CH-1015, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I." last="Boomsma">Dorret I. Boomsma</name><affiliation wicri:level="3"><nlm:aff id="A46">Department of Biological Psychology, VU University Amsterdam, van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Biological Psychology, VU University Amsterdam, van der Boechorststraat 1, 1081 BT, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Buring, Julie E" sort="Buring, Julie E" uniqKey="Buring J" first="Julie E." last="Buring">Julie E. Buring</name><affiliation wicri:level="2"><nlm:aff id="A8">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, MA 02215</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Division of Preventive Medicine, Brigham and Women’s Hospital, Boston</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A9">Harvard Medical School, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Harvard Medical School, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name><affiliation wicri:level="1"><nlm:aff id="A51">Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21224, United States of America</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21224</wicri:regionArea><wicri:noRegion>Maryland 21224</wicri:noRegion></affiliation></author><author><name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W." last="Montgomery">Grant W. Montgomery</name><affiliation wicri:level="1"><nlm:aff id="A131">QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>QIMR Berghofer Medical Research Institute, Brisbane, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation wicri:level="1"><nlm:aff id="A49">Icelandic Heart Association, Kopavogur, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A50">Faculty of Medicine, University of Iceland, IS-101 Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, IS-101 Reykjavik</wicri:regionArea><wicri:noRegion>IS-101 Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D." last="Spector">Tim D. Spector</name><affiliation wicri:level="1"><nlm:aff id="A47">Department of Twin Research and Genetic Epidemiology, King’s College London, London SE1 7EH, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Twin Research and Genetic Epidemiology, King’s College London, London SE1 7EH</wicri:regionArea><wicri:noRegion>London SE1 7EH</wicri:noRegion></affiliation></author><author><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name><affiliation wicri:level="3"><nlm:aff id="A43">Genetic Epidemiology Unit Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Genetic Epidemiology Unit Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Alizadeh, Behrooz Z" sort="Alizadeh, Behrooz Z" uniqKey="Alizadeh B" first="Behrooz Z." last="Alizadeh">Behrooz Z. Alizadeh</name><affiliation wicri:level="4"><nlm:aff id="A172">Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region><settlement type="city">Groningue (ville)</settlement></placeName><orgName type="university">Université de Groningue</orgName></affiliation></author><author><name sortKey="Ciullo, Marina" sort="Ciullo, Marina" uniqKey="Ciullo M" first="Marina" last="Ciullo">Marina Ciullo</name><affiliation wicri:level="1"><nlm:aff id="A32">Institute of Genetics and Biophysics - CNR, via Pietro Castellino 111, 80131, Naples, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Genetics and Biophysics - CNR, via Pietro Castellino 111, 80131, Naples</wicri:regionArea><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Crisponi, Laura" sort="Crisponi, Laura" uniqKey="Crisponi L" first="Laura" last="Crisponi">Laura Crisponi</name><affiliation wicri:level="1"><nlm:aff id="A33">Institute of Genetics and Biomedical Research, National Research Council, Cagliari, 09042 Sardinia, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Genetics and Biomedical Research, National Research Council, Cagliari, 09042 Sardinia</wicri:regionArea><wicri:noRegion>09042 Sardinia</wicri:noRegion></affiliation></author><author><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name><affiliation wicri:level="4"><nlm:aff id="A3">Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A93">Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, CB1 8RN</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Gasparini, Paolo P" sort="Gasparini, Paolo P" uniqKey="Gasparini P" first="Paolo P." last="Gasparini">Paolo P. Gasparini</name><affiliation wicri:level="1"><nlm:aff id="A36">Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste</wicri:regionArea><wicri:noRegion>34137 Trieste</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A41">Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, 34149 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Medical Sciences, Surgical and Health, University of Trieste, 34149 Trieste</wicri:regionArea><wicri:noRegion>34149 Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><affiliation wicri:level="1"><nlm:aff id="A24">Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A25">Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A26">Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, 85764 Neuherberg</wicri:regionArea><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion><wicri:noRegion>85764 Neuherberg</wicri:noRegion></affiliation></author><author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B." last="Harris">Tamara B. Harris</name><affiliation wicri:level="2"><nlm:aff id="A99">Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name><affiliation wicri:level="4"><nlm:aff id="A29">Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU</wicri:regionArea><orgName type="university">Université d'Édimbourg</orgName><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Kardia, Sharon L R" sort="Kardia, Sharon L R" uniqKey="Kardia S" first="Sharon L. R." last="Kardia">Sharon L. R. Kardia</name><affiliation wicri:level="2"><nlm:aff id="A38">Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Kraft, Peter" sort="Kraft, Peter" uniqKey="Kraft P" first="Peter" last="Kraft">Peter Kraft</name><affiliation wicri:level="2"><nlm:aff id="A12">Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A173">Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Mcknight, Barbara" sort="Mcknight, Barbara" uniqKey="Mcknight B" first="Barbara" last="Mcknight">Barbara Mcknight</name><affiliation wicri:level="4"><nlm:aff id="A56">Department of Biostatistics, University of Washington, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biostatistics, University of Washington, Seattle, WA</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Metspalu, Andres" sort="Metspalu, Andres" uniqKey="Metspalu A" first="Andres" last="Metspalu">Andres Metspalu</name><affiliation wicri:level="1"><nlm:aff id="A6">Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia</nlm:aff><country xml:lang="fr">Estonie</country><wicri:regionArea>Estonian Genome Center, University of Tartu, Tartu, 51010</wicri:regionArea><wicri:noRegion>51010</wicri:noRegion></affiliation></author><author><name sortKey="Morrison, Alanna C" sort="Morrison, Alanna C" uniqKey="Morrison A" first="Alanna C." last="Morrison">Alanna C. Morrison</name><affiliation wicri:level="2"><nlm:aff id="A64">Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Reiner, Alex P" sort="Reiner, Alex P" uniqKey="Reiner A" first="Alex P." last="Reiner">Alex P. Reiner</name><affiliation wicri:level="2"><nlm:aff id="A37">Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Seattle, WA 98109-1024, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Seattle, WA 98109-1024</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A144">Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA 98195, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA 98195</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Ridker, Paul M" sort="Ridker, Paul M" uniqKey="Ridker P" first="Paul M." last="Ridker">Paul M. Ridker</name><affiliation wicri:level="2"><nlm:aff id="A8">Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, MA 02215</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Division of Preventive Medicine, Brigham and Women’s Hospital, Boston</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A9">Harvard Medical School, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Harvard Medical School, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Rotter, Jerome I" sort="Rotter, Jerome I" uniqKey="Rotter J" first="Jerome I." last="Rotter">Jerome I. Rotter</name><affiliation wicri:level="2"><nlm:aff id="A42">The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Toniolo, Daniela" sort="Toniolo, Daniela" uniqKey="Toniolo D" first="Daniela" last="Toniolo">Daniela Toniolo</name><affiliation wicri:level="1"><nlm:aff id="A40">Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132 Milano</wicri:regionArea><wicri:noRegion>20132 Milano</wicri:noRegion></affiliation></author><author><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G." last="Uitterlinden">André G. Uitterlinden</name><affiliation wicri:level="1"><nlm:aff id="A10">Department of Internal Medicine, Erasmus MC, 3015GE Rotterdam, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus MC, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A11">Netherlands Consortium on Health Aging and National Genomics Initiative, 2300 RC Leiden, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherlands Consortium on Health Aging and National Genomics Initiative, 2300 RC Leiden</wicri:regionArea><wicri:noRegion>2300 RC Leiden</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A43">Genetic Epidemiology Unit Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Genetic Epidemiology Unit Department of Epidemiology, Erasmus MC, 3015 GE, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Ulivi, Sheila" sort="Ulivi, Sheila" uniqKey="Ulivi S" first="Sheila" last="Ulivi">Sheila Ulivi</name><affiliation wicri:level="1"><nlm:aff id="A36">Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, 34137 Trieste</wicri:regionArea><wicri:noRegion>34137 Trieste</wicri:noRegion></affiliation></author><author><name sortKey="Volzke, Henry" sort="Volzke, Henry" uniqKey="Volzke H" first="Henry" last="Völzke">Henry Völzke</name><affiliation wicri:level="1"><nlm:aff id="A39">Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald</wicri:regionArea><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion><wicri:noRegion>17475 Greifswald</wicri:noRegion></affiliation></author><author><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J." last="Wareham">Nicholas J. Wareham</name><affiliation wicri:level="1"><nlm:aff id="A1"> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ</wicri:regionArea><wicri:noRegion>CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Weir, David R" sort="Weir, David R" uniqKey="Weir D" first="David R." last="Weir">David R. Weir</name><affiliation wicri:level="2"><nlm:aff id="A95">Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Yerges Armstrong, Laura M" sort="Yerges Armstrong, Laura M" uniqKey="Yerges Armstrong L" first="Laura M." last="Yerges-Armstrong">Laura M. Yerges-Armstrong</name><affiliation wicri:level="2"><nlm:aff id="A31">Program in Personalized Medicine, Division of Endocrinology, Diabetes and Nutrition - University of Maryland School of Medicine, USA. Baltimore, MD 21201</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Program in Personalized Medicine, Division of Endocrinology, Diabetes and Nutrition - University of Maryland School of Medicine, USA. Baltimore</wicri:cityArea></affiliation></author><author><name sortKey="Price, Alkes L" sort="Price, Alkes L" uniqKey="Price A" first="Alkes L." last="Price">Alkes L. Price</name><affiliation wicri:level="2"><nlm:aff id="A12">Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Stefansson, Kari" sort="Stefansson, Kari" uniqKey="Stefansson K" first="Kari" last="Stefansson">Kari Stefansson</name><affiliation wicri:level="1"><nlm:aff id="A14">deCODE genetics/Amgen, Inc., IS-101 Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>deCODE genetics/Amgen, Inc., IS-101 Reykjavik</wicri:regionArea><wicri:noRegion>IS-101 Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A50">Faculty of Medicine, University of Iceland, IS-101 Reykjavik, Iceland</nlm:aff><country xml:lang="fr">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, IS-101 Reykjavik</wicri:regionArea><wicri:noRegion>IS-101 Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Visser, Jenny A" sort="Visser, Jenny A" uniqKey="Visser J" first="Jenny A." last="Visser">Jenny A. Visser</name><affiliation wicri:level="1"><nlm:aff id="A10">Department of Internal Medicine, Erasmus MC, 3015GE Rotterdam, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Internal Medicine, Erasmus MC, 3015GE Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Ong, Ken K" sort="Ong, Ken K" uniqKey="Ong K" first="Ken K." last="Ong">Ken K. Ong</name><affiliation wicri:level="1"><nlm:aff id="A1"> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ</wicri:regionArea><wicri:noRegion>CB2 0QQ</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A176">Department of Paediatrics,University of Cambridge,Cambridge, CB2 0QQ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Paediatrics,University of Cambridge,Cambridge, CB2 0QQ</wicri:regionArea><wicri:noRegion>CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Chang Claude, Jenny" sort="Chang Claude, Jenny" uniqKey="Chang Claude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><affiliation wicri:level="3"><nlm:aff id="A152">Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Murabito, Joanne M" sort="Murabito, Joanne M" uniqKey="Murabito J" first="Joanne M." last="Murabito">Joanne M. Murabito</name><affiliation wicri:level="1"><nlm:aff id="A5">NHLBI’s and Boston University’s Framingham Heart Study, Framingham, Massachusetts 01702-5827, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>NHLBI’s and Boston University’s Framingham Heart Study, Framingham, Massachusetts 01702-5827</wicri:regionArea><wicri:noRegion>Massachusetts 01702-5827</wicri:noRegion></affiliation><affiliation wicri:level="2"><nlm:aff id="A177">Boston University School of Medicine, Department of Medicine, Section of General Internal Medicine, Boston, MA 02118, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Boston University School of Medicine, Department of Medicine, Section of General Internal Medicine, Boston, MA 02118</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Perry, John R B" sort="Perry, John R B" uniqKey="Perry J" first="John R. B." last="Perry">John R. B. Perry</name><affiliation wicri:level="1"><nlm:aff id="A1"> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea> MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ</wicri:regionArea><wicri:noRegion>CB2 0QQ</wicri:noRegion></affiliation></author><author><name sortKey="Murray, Anna" sort="Murray, Anna" uniqKey="Murray A" first="Anna" last="Murray">Anna Murray</name><affiliation wicri:level="1"><nlm:aff id="A2">Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW</wicri:regionArea><wicri:noRegion>EX2 5DW</wicri:noRegion></affiliation></author></analytic><series><title level="j">Nature genetics</title><idno type="ISSN">1061-4036</idno><idno type="eISSN">1546-1718</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Age Factors</term><term>Aging (genetics)</term><term>BRCA1 Protein (genetics)</term><term>Breast Neoplasms (genetics)</term><term>DNA Repair</term><term>Female</term><term>Gene Regulatory Networks (genetics)</term><term>Genetic Predisposition to Disease (genetics)</term><term>Genetic Variation</term><term>Genome-Wide Association Study (methods)</term><term>Genomics (methods)</term><term>Genotype</term><term>Humans</term><term>Hypothalamus (metabolism)</term><term>Menopause (genetics)</term><term>Middle Aged</term><term>Models, Genetic</term><term>Phenotype</term><term>Reproduction (genetics)</term><term>Signal Transduction (genetics)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Facteurs de l'âge</term><term>Femelle</term><term>Génomique ()</term><term>Génotype</term><term>Humains</term><term>Hypothalamus (métabolisme)</term><term>Modèles génétiques</term><term>Ménopause (génétique)</term><term>Phénotype</term><term>Protéine BRCA1 (génétique)</term><term>Prédisposition génétique à une maladie (génétique)</term><term>Reproduction (génétique)</term><term>Réparation de l'ADN</term><term>Réseaux de régulation génique (génétique)</term><term>Transduction du signal (génétique)</term><term>Tumeurs du sein (génétique)</term><term>Variation génétique</term><term>Vieillissement (génétique)</term><term>Étude d'association pangénomique ()</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>BRCA1 Protein</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Aging</term><term>Breast Neoplasms</term><term>Gene Regulatory Networks</term><term>Genetic Predisposition to Disease</term><term>Menopause</term><term>Reproduction</term><term>Signal Transduction</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Ménopause</term><term>Protéine BRCA1</term><term>Prédisposition génétique à une maladie</term><term>Reproduction</term><term>Réseaux de régulation génique</term><term>Transduction du signal</term><term>Tumeurs du sein</term><term>Vieillissement</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Hypothalamus</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Genome-Wide Association Study</term><term>Genomics</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Hypothalamus</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Age Factors</term><term>DNA Repair</term><term>Female</term><term>Genetic Variation</term><term>Genotype</term><term>Humans</term><term>Middle Aged</term><term>Models, Genetic</term><term>Phenotype</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Facteurs de l'âge</term><term>Femelle</term><term>Génomique</term><term>Génotype</term><term>Humains</term><term>Modèles génétiques</term><term>Phénotype</term><term>Réparation de l'ADN</term><term>Variation génétique</term><term>Étude d'association pangénomique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P12">Menopause timing has a substantial impact on infertility and risk of disease, including breast cancer, but the underlying mechanisms are poorly understood. We report a dual strategy in <sup>~</sup>70,000 women to identify common and low-frequency protein-coding variation associated with age at natural menopause (ANM). We identified 44 regions with common variants, including two harbouring additional rare missense alleles of large effect. We found enrichment of signals in/near genes involved in delayed puberty, highlighting the first molecular links between the onset and end of reproductive lifespan. Pathway analyses revealed a major association with DNA damage-response (DDR) genes, including the first common coding variant in <italic>BRCA1</italic> associated with any complex trait. Mendelian randomisation analyses supported a causal effect of later ANM on breast cancer risk (<sup>~</sup>6% risk increase per-year, P=3×10<sup>−14</sup>), likely mediated by prolonged sex hormone exposure, rather than DDR mechanisms.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Hartge, P" uniqKey="Hartge P">P Hartge</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lambalk, Cb" uniqKey="Lambalk C">CB Lambalk</name></author><author><name sortKey="Van Disseldorp, J" uniqKey="Van Disseldorp J">J van Disseldorp</name></author><author><name sortKey="De Koning, Ch" uniqKey="De Koning C">CH de Koning</name></author><author><name sortKey="Broekmans, Fj" uniqKey="Broekmans F">FJ Broekmans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Te Velde, Er" uniqKey="Te Velde E">ER te Velde</name></author><author><name sortKey="Pearson, Pl" uniqKey="Pearson P">PL 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Gaytan</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Belgique</li><li>Canada</li><li>Croatie</li><li>Danemark</li><li>Espagne</li><li>Estonie</li><li>Finlande</li><li>France</li><li>Grèce</li><li>Islande</li><li>Italie</li><li>Norvège</li><li>Pays-Bas</li><li>Pologne</li><li>Royaume-Uni</li><li>République populaire de Chine</li><li>Suisse</li><li>Suède</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Angleterre de l'Est</li><li>Attique (région)</li><li>Bade-Wurtemberg</li><li>Basse-Saxe</li><li>Bavière</li><li>Californie</li><li>Canton de Vaud</li><li>Caroline du Nord</li><li>Communauté de Madrid</li><li>District de Haute-Bavière</li><li>District de Karlsruhe</li><li>District de Moyenne-Franconie</li><li>District de Stuttgart</li><li>District de Tübingen</li><li>Grand Londres</li><li>Groningue (province)</li><li>Hambourg</li><li>Hollande-Méridionale</li><li>Hollande-Septentrionale</li><li>Hovedstaden</li><li>Indiana</li><li>Lombardie</li><li>Maryland</li><li>Massachusetts</li><li>Michigan</li><li>Minnesota</li><li>Ohio</li><li>Ontario</li><li>Oxfordshire</li><li>Pennsylvanie</li><li>Québec</li><li>Svealand</li><li>Tennessee</li><li>Texas</li><li>Victoria (État)</li><li>Washington (État)</li><li>Écosse</li><li>Østlandet</li></region><settlement><li>Amsterdam</li><li>Athènes</li><li>Cambridge</li><li>Copenhague</li><li>Erlangen</li><li>Glasgow</li><li>Groningue</li><li>Groningue (ville)</li><li>Hambourg</li><li>Hanovre</li><li>Heidelberg</li><li>Lausanne</li><li>Londres</li><li>Los Angeles</li><li>Madrid</li><li>Melbourne</li><li>Milan</li><li>Montréal</li><li>Munich</li><li>Oslo</li><li>Oxford</li><li>Pittsburgh</li><li>Rotterdam</li><li>Seattle</li><li>Stockholm</li><li>Stuttgart</li><li>Toronto</li><li>Tübingen</li><li>Édimbourg</li></settlement><orgName><li>Université McGill</li><li>Université d'Oxford</li><li>Université d'Édimbourg</li><li>Université de Californie du Sud</li><li>Université de Cambridge</li><li>Université de Glasgow</li><li>Université de Groningue</li><li>Université de Melbourne</li><li>Université de Pittsburgh</li><li>Université de Toronto</li><li>Université de Washington</li><li>Université technique de Munich</li></orgName></list><tree><noCountry><name sortKey="Liu, Yongmei" sort="Liu, Yongmei" uniqKey="Liu Y" first="Yongmei" last="Liu">Yongmei Liu</name></noCountry><country name="Royaume-Uni"><noRegion><name sortKey="Day, Felix R" sort="Day, Felix R" uniqKey="Day F" first="Felix R." last="Day">Felix R. Day</name></noRegion><name sortKey="Antoniou, Antonis C" sort="Antoniou, Antonis C" uniqKey="Antoniou A" first="Antonis C." last="Antoniou">Antonis C. Antoniou</name><name sortKey="Bolla, Manjeet K" sort="Bolla, Manjeet K" uniqKey="Bolla M" first="Manjeet K." last="Bolla">Manjeet K. Bolla</name><name sortKey="Boutin, Thibaud S" sort="Boutin, Thibaud S" uniqKey="Boutin T" first="Thibaud S" last="Boutin">Thibaud S. Boutin</name><name sortKey="Campbell, Archie" sort="Campbell, Archie" uniqKey="Campbell A" first="Archie" last="Campbell">Archie Campbell</name><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><name sortKey="Chapman, J Ross" sort="Chapman, J Ross" uniqKey="Chapman J" first="J. Ross" last="Chapman">J. Ross Chapman</name><name sortKey="Cox, Angela" sort="Cox, Angela" uniqKey="Cox A" first="Angela" last="Cox">Angela Cox</name><name sortKey="Dennis, Joe" sort="Dennis, Joe" uniqKey="Dennis J" first="Joe" last="Dennis">Joe Dennis</name><name sortKey="Dos Santos Silva, Isabel" sort="Dos Santos Silva, Isabel" uniqKey="Dos Santos Silva I" first="Isabel" last="Dos-Santos-Silva">Isabel Dos-Santos-Silva</name><name sortKey="Dunning, Alison M" sort="Dunning, Alison M" uniqKey="Dunning A" first="Alison M." last="Dunning">Alison M. Dunning</name><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name><name sortKey="Easton, Douglas F" sort="Easton, Douglas F" uniqKey="Easton D" first="Douglas F." last="Easton">Douglas F. Easton</name><name sortKey="Elks, Cathy E" sort="Elks, Cathy E" uniqKey="Elks C" first="Cathy E." last="Elks">Cathy E. Elks</name><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="García-Closas">Montserrat García-Closas</name><name sortKey="Garcia Closas, Montserrat" sort="Garcia Closas, Montserrat" uniqKey="Garcia Closas M" first="Montserrat" last="García-Closas">Montserrat García-Closas</name><name sortKey="Hayward, Caroline" sort="Hayward, Caroline" uniqKey="Hayward C" first="Caroline" last="Hayward">Caroline Hayward</name><name sortKey="Hocking, Lynne J" sort="Hocking, Lynne J" uniqKey="Hocking L" first="Lynne J." last="Hocking">Lynne J. Hocking</name><name sortKey="Huffman, Jennifer E" sort="Huffman, Jennifer E" uniqKey="Huffman J" first="Jennifer E." last="Huffman">Jennifer E. Huffman</name><name sortKey="Jones, Samuel E" sort="Jones, Samuel E" uniqKey="Jones S" first="Samuel E." last="Jones">Samuel E. Jones</name><name sortKey="Langenberg, Claudia" sort="Langenberg, Claudia" uniqKey="Langenberg C" first="Claudia" last="Langenberg">Claudia Langenberg</name><name sortKey="Luan, Jian N" sort="Luan, Jian N" uniqKey="Luan J" first="Jian N" last="Luan">Jian N Luan</name><name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name><name sortKey="Mangino, Massimo" sort="Mangino, Massimo" uniqKey="Mangino M" first="Massimo" last="Mangino">Massimo Mangino</name><name sortKey="Marten, Jonathan" sort="Marten, Jonathan" uniqKey="Marten J" first="Jonathan" last="Marten">Jonathan Marten</name><name sortKey="Michailidou, Kyriaki" sort="Michailidou, Kyriaki" uniqKey="Michailidou K" first="Kyriaki" last="Michailidou">Kyriaki Michailidou</name><name sortKey="Murray, Anna" sort="Murray, Anna" uniqKey="Murray A" first="Anna" last="Murray">Anna Murray</name><name sortKey="Ong, Ken K" sort="Ong, Ken K" uniqKey="Ong K" first="Ken K." last="Ong">Ken K. Ong</name><name sortKey="Ong, Ken K" sort="Ong, Ken K" uniqKey="Ong K" first="Ken K." last="Ong">Ken K. Ong</name><name sortKey="Padmanabhan, Sandosh" sort="Padmanabhan, Sandosh" uniqKey="Padmanabhan S" first="Sandosh" last="Padmanabhan">Sandosh Padmanabhan</name><name sortKey="Perry, John R B" sort="Perry, John R B" uniqKey="Perry J" first="John R. B." last="Perry">John R. B. Perry</name><name sortKey="Peto, Julian" sort="Peto, Julian" uniqKey="Peto J" first="Julian" last="Peto">Julian Peto</name><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name><name sortKey="Pharoah, Paul D P" sort="Pharoah, Paul D P" uniqKey="Pharoah P" first="Paul D. P." last="Pharoah">Paul D. P. Pharoah</name><name sortKey="Pirie, Ailith" sort="Pirie, Ailith" uniqKey="Pirie A" first="Ailith" last="Pirie">Ailith Pirie</name><name sortKey="Porteous, David" sort="Porteous, David" uniqKey="Porteous D" first="David" last="Porteous">David Porteous</name><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><name sortKey="Ruth, Katherine S" sort="Ruth, Katherine S" uniqKey="Ruth K" first="Katherine S." last="Ruth">Katherine S. Ruth</name><name sortKey="Sawyer, Elinor J" sort="Sawyer, Elinor J" uniqKey="Sawyer E" first="Elinor J." last="Sawyer">Elinor J. Sawyer</name><name sortKey="Schoemaker, Minouk J" sort="Schoemaker, Minouk J" uniqKey="Schoemaker M" first="Minouk J." last="Schoemaker">Minouk J. Schoemaker</name><name sortKey="Scott, Robert A" sort="Scott, Robert A" uniqKey="Scott R" first="Robert A." last="Scott">Robert A. Scott</name><name sortKey="Spector, Tim D" sort="Spector, Tim D" uniqKey="Spector T" first="Tim D." last="Spector">Tim D. Spector</name><name sortKey="Swerdlow, Anthony" sort="Swerdlow, Anthony" uniqKey="Swerdlow A" first="Anthony" last="Swerdlow">Anthony Swerdlow</name><name sortKey="Swerdlow, Anthony" sort="Swerdlow, Anthony" uniqKey="Swerdlow A" first="Anthony" last="Swerdlow">Anthony Swerdlow</name><name sortKey="Thompson, Deborah J" sort="Thompson, Deborah J" uniqKey="Thompson D" first="Deborah J." last="Thompson">Deborah J. Thompson</name><name sortKey="Tomlinson, Ian" sort="Tomlinson, Ian" uniqKey="Tomlinson I" first="Ian" last="Tomlinson">Ian Tomlinson</name><name sortKey="Tomlinson, Ian" sort="Tomlinson, Ian" uniqKey="Tomlinson I" first="Ian" last="Tomlinson">Ian Tomlinson</name><name sortKey="Wang, Qin" sort="Wang, Qin" uniqKey="Wang Q" first="Qin" last="Wang">Qin Wang</name><name sortKey="Wareham, Nicholas J" sort="Wareham, Nicholas J" uniqKey="Wareham N" first="Nicholas J." last="Wareham">Nicholas J. Wareham</name><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F." last="Wilson">James F. Wilson</name><name sortKey="Wilson, James F" sort="Wilson, James F" uniqKey="Wilson J" first="James F." last="Wilson">James F. Wilson</name><name sortKey="Wright, Alan F" sort="Wright, Alan F" uniqKey="Wright A" first="Alan F." last="Wright">Alan F. Wright</name></country><country name="États-Unis"><noRegion><name sortKey="Lunetta, Kathryn L" sort="Lunetta, Kathryn L" uniqKey="Lunetta K" first="Kathryn L." last="Lunetta">Kathryn L. Lunetta</name></noRegion><name sortKey="Abecasis, Goncalo" sort="Abecasis, Goncalo" uniqKey="Abecasis G" first="Goncalo" last="Abecasis">Goncalo Abecasis</name><name sortKey="Anton Culver, Hoda" sort="Anton Culver, Hoda" uniqKey="Anton Culver H" first="Hoda" last="Anton-Culver">Hoda Anton-Culver</name><name sortKey="Arnold, Alice M" sort="Arnold, Alice M" uniqKey="Arnold A" first="Alice M." last="Arnold">Alice M. Arnold</name><name sortKey="Beeghly Fadiel, Alicia" sort="Beeghly Fadiel, Alicia" uniqKey="Beeghly Fadiel A" first="Alicia" last="Beeghly-Fadiel">Alicia Beeghly-Fadiel</name><name sortKey="Bernstein, Leslie" sort="Bernstein, Leslie" uniqKey="Bernstein L" first="Leslie" last="Bernstein">Leslie Bernstein</name><name sortKey="Bielinski, Suzette J" sort="Bielinski, Suzette J" uniqKey="Bielinski S" first="Suzette J." last="Bielinski">Suzette J. Bielinski</name><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><name sortKey="Brody, Jennifer A" sort="Brody, Jennifer A" uniqKey="Brody J" first="Jennifer A." last="Brody">Jennifer A. Brody</name><name sortKey="Bulik Sullivan, Brendan" sort="Bulik Sullivan, Brendan" uniqKey="Bulik Sullivan B" first="Brendan" last="Bulik-Sullivan">Brendan Bulik-Sullivan</name><name sortKey="Bulik Sullivan, Brendan" sort="Bulik Sullivan, Brendan" uniqKey="Bulik Sullivan B" first="Brendan" last="Bulik-Sullivan">Brendan Bulik-Sullivan</name><name sortKey="Bulik Sullivan, Brendan" sort="Bulik Sullivan, Brendan" uniqKey="Bulik Sullivan B" first="Brendan" last="Bulik-Sullivan">Brendan Bulik-Sullivan</name><name sortKey="Buring, Julie E" sort="Buring, Julie E" uniqKey="Buring J" first="Julie E." last="Buring">Julie E. Buring</name><name sortKey="Buring, Julie E" sort="Buring, Julie E" uniqKey="Buring J" first="Julie E." last="Buring">Julie E. Buring</name><name sortKey="Chanock, Stephen J" sort="Chanock, Stephen J" uniqKey="Chanock S" first="Stephen J." last="Chanock">Stephen J. Chanock</name><name sortKey="Chasman, Daniel I" sort="Chasman, Daniel I" uniqKey="Chasman D" first="Daniel I." last="Chasman">Daniel I. Chasman</name><name sortKey="Chen, Yii Der Ida" sort="Chen, Yii Der Ida" uniqKey="Chen Y" first="Yii-Der Ida" last="Chen">Yii-Der Ida Chen</name><name sortKey="Couch, Fergus J" sort="Couch, Fergus J" uniqKey="Couch F" first="Fergus J." last="Couch">Fergus J. Couch</name><name sortKey="Coviello, Andrea D" sort="Coviello, Andrea D" uniqKey="Coviello A" first="Andrea D." last="Coviello">Andrea D. Coviello</name><name sortKey="De Vivo, Immaculata" sort="De Vivo, Immaculata" uniqKey="De Vivo I" first="Immaculata" last="De Vivo">Immaculata De Vivo</name><name sortKey="De Vivo, Immaculata" sort="De Vivo, Immaculata" uniqKey="De Vivo I" first="Immaculata" last="De Vivo">Immaculata De Vivo</name><name sortKey="Demerath, Ellen W" sort="Demerath, Ellen W" uniqKey="Demerath E" first="Ellen W." last="Demerath">Ellen W. 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Olson</name><name sortKey="Peters, Ulrike" sort="Peters, Ulrike" uniqKey="Peters U" first="Ulrike" last="Peters">Ulrike Peters</name><name sortKey="Pistis, Giorgio" sort="Pistis, Giorgio" uniqKey="Pistis G" first="Giorgio" last="Pistis">Giorgio Pistis</name><name sortKey="Porcu, Eleonora" sort="Porcu, Eleonora" uniqKey="Porcu E" first="Eleonora" last="Porcu">Eleonora Porcu</name><name sortKey="Price, Alkes L" sort="Price, Alkes L" uniqKey="Price A" first="Alkes L." last="Price">Alkes L. Price</name><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M." last="Psaty">Bruce M. Psaty</name><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M." last="Psaty">Bruce M. Psaty</name><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M." last="Psaty">Bruce M. Psaty</name><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M." last="Psaty">Bruce M. Psaty</name><name sortKey="Raffel, Leslie J" sort="Raffel, Leslie J" uniqKey="Raffel L" first="Leslie J." last="Raffel">Leslie J. Raffel</name><name sortKey="Raffel, Leslie J" sort="Raffel, Leslie J" uniqKey="Raffel L" first="Leslie J." last="Raffel">Leslie J. Raffel</name><name sortKey="Reiner, Alex P" sort="Reiner, Alex P" uniqKey="Reiner A" first="Alex P." last="Reiner">Alex P. Reiner</name><name sortKey="Reiner, Alex P" sort="Reiner, Alex P" uniqKey="Reiner A" first="Alex P." last="Reiner">Alex P. Reiner</name><name sortKey="Ridker, Paul M" sort="Ridker, Paul M" uniqKey="Ridker P" first="Paul M." last="Ridker">Paul M. Ridker</name><name sortKey="Ridker, Paul M" sort="Ridker, Paul M" uniqKey="Ridker P" first="Paul M." last="Ridker">Paul M. Ridker</name><name sortKey="Rose, Lynda M" sort="Rose, Lynda M" uniqKey="Rose L" first="Lynda M." last="Rose">Lynda M. 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Yerges-Armstrong</name><name sortKey="Zhao, Wei" sort="Zhao, Wei" uniqKey="Zhao W" first="Wei" last="Zhao">Wei Zhao</name><name sortKey="Zheng, Wei" sort="Zheng, Wei" uniqKey="Zheng W" first="Wei" last="Zheng">Wei Zheng</name></country><country name="Estonie"><noRegion><name sortKey="Pervjakova, Natalia" sort="Pervjakova, Natalia" uniqKey="Pervjakova N" first="Natalia" last="Pervjakova">Natalia Pervjakova</name></noRegion><name sortKey="Esko, T Nu" sort="Esko, T Nu" uniqKey="Esko T" first="T Nu" last="Esko">T Nu Esko</name><name sortKey="M Gi, Reedik" sort="M Gi, Reedik" uniqKey="M Gi R" first="Reedik" last="M Gi">Reedik M Gi</name><name sortKey="Metspalu, Andres" sort="Metspalu, Andres" uniqKey="Metspalu A" first="Andres" last="Metspalu">Andres Metspalu</name><name sortKey="Mihailov, Evelin" sort="Mihailov, Evelin" uniqKey="Mihailov E" first="Evelin" last="Mihailov">Evelin Mihailov</name><name sortKey="Milani, Lili" sort="Milani, Lili" uniqKey="Milani L" first="Lili" last="Milani">Lili Milani</name><name sortKey="Pervjakova, Natalia" sort="Pervjakova, Natalia" uniqKey="Pervjakova N" first="Natalia" last="Pervjakova">Natalia Pervjakova</name></country><country name="Pays-Bas"><region name="Hollande-Méridionale"><name sortKey="Stolk, Lisette" sort="Stolk, Lisette" uniqKey="Stolk L" first="Lisette" last="Stolk">Lisette Stolk</name></region><name sortKey="Alizadeh, Behrooz Z" sort="Alizadeh, Behrooz Z" uniqKey="Alizadeh B" first="Behrooz Z." last="Alizadeh">Behrooz Z. Alizadeh</name><name sortKey="Amin, Najaf" sort="Amin, Najaf" uniqKey="Amin N" first="Najaf" last="Amin">Najaf Amin</name><name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I." last="Boomsma">Dorret I. Boomsma</name><name sortKey="Devilee, Peter" sort="Devilee, Peter" uniqKey="Devilee P" first="Peter" last="Devilee">Peter Devilee</name><name sortKey="Devilee, Peter" sort="Devilee, Peter" uniqKey="Devilee P" first="Peter" last="Devilee">Peter Devilee</name><name sortKey="Franke, Lude L" sort="Franke, Lude L" uniqKey="Franke L" first="Lude L." last="Franke">Lude L. Franke</name><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><name sortKey="Hooning, Maartje J" sort="Hooning, Maartje J" uniqKey="Hooning M" first="Maartje J." last="Hooning">Maartje J. Hooning</name><name sortKey="Hottenga, Jouke Jan" sort="Hottenga, Jouke Jan" uniqKey="Hottenga J" first="Jouke-Jan" last="Hottenga">Jouke-Jan Hottenga</name><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><name sortKey="Rivadeneira, Fernando" sort="Rivadeneira, Fernando" uniqKey="Rivadeneira F" first="Fernando" last="Rivadeneira">Fernando Rivadeneira</name><name sortKey="Schmidt, Marjanka K" sort="Schmidt, Marjanka K" uniqKey="Schmidt M" first="Marjanka K." last="Schmidt">Marjanka K. Schmidt</name><name sortKey="Seynaeve, Caroline M" sort="Seynaeve, Caroline M" uniqKey="Seynaeve C" first="Caroline M." last="Seynaeve">Caroline M. Seynaeve</name><name sortKey="Stolk, Lisette" sort="Stolk, Lisette" uniqKey="Stolk L" first="Lisette" last="Stolk">Lisette Stolk</name><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G." last="Uitterlinden">André G. Uitterlinden</name><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G." last="Uitterlinden">André G. Uitterlinden</name><name sortKey="Uitterlinden, Andre G" sort="Uitterlinden, Andre G" uniqKey="Uitterlinden A" first="André G." last="Uitterlinden">André G. Uitterlinden</name><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name><name sortKey="Visser, Jenny A" sort="Visser, Jenny A" uniqKey="Visser J" first="Jenny A." last="Visser">Jenny A. Visser</name><name sortKey="Willemsen, Gonneke" sort="Willemsen, Gonneke" uniqKey="Willemsen G" first="Gonneke" last="Willemsen">Gonneke Willemsen</name><name sortKey="Wolffenbuttel, Bruce B H R" sort="Wolffenbuttel, Bruce B H R" uniqKey="Wolffenbuttel B" first="Bruce B. H. R." last="Wolffenbuttel">Bruce B. H. R. Wolffenbuttel</name><name sortKey="Wolffenbuttel, Bruce B H R" sort="Wolffenbuttel, Bruce B H R" uniqKey="Wolffenbuttel B" first="Bruce B. H. R." last="Wolffenbuttel">Bruce B. H. R. Wolffenbuttel</name></country><country name="Islande"><noRegion><name sortKey="Sulem, Patrick" sort="Sulem, Patrick" uniqKey="Sulem P" first="Patrick" last="Sulem">Patrick Sulem</name></noRegion><name sortKey="Gudbjartsson, Daniel F" sort="Gudbjartsson, Daniel F" uniqKey="Gudbjartsson D" first="Daniel F." last="Gudbjartsson">Daniel F. Gudbjartsson</name><name sortKey="Gudbjartsson, Daniel F" sort="Gudbjartsson, Daniel F" uniqKey="Gudbjartsson D" first="Daniel F." last="Gudbjartsson">Daniel F. Gudbjartsson</name><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><name sortKey="Smith, Albert V" sort="Smith, Albert V" uniqKey="Smith A" first="Albert V." last="Smith">Albert V. Smith</name><name sortKey="Smith, Albert V" sort="Smith, Albert V" uniqKey="Smith A" first="Albert V." last="Smith">Albert V. Smith</name><name sortKey="Stefansson, Kari" sort="Stefansson, Kari" uniqKey="Stefansson K" first="Kari" last="Stefansson">Kari Stefansson</name><name sortKey="Stefansson, Kari" sort="Stefansson, Kari" uniqKey="Stefansson K" first="Kari" last="Stefansson">Kari Stefansson</name><name sortKey="Thorsteinsdottir, Unnur" sort="Thorsteinsdottir, Unnur" uniqKey="Thorsteinsdottir U" first="Unnur" last="Thorsteinsdottir">Unnur Thorsteinsdottir</name><name sortKey="Thorsteinsdottir, Unnur" sort="Thorsteinsdottir, Unnur" uniqKey="Thorsteinsdottir U" first="Unnur" last="Thorsteinsdottir">Unnur Thorsteinsdottir</name><name sortKey="Tryggvadottir, Laufey" sort="Tryggvadottir, Laufey" uniqKey="Tryggvadottir L" first="Laufey" last="Tryggvadottir">Laufey Tryggvadottir</name></country><country name="Allemagne"><noRegion><name sortKey="Altmaier, Elisabeth" sort="Altmaier, Elisabeth" uniqKey="Altmaier E" first="Elisabeth" last="Altmaier">Elisabeth Altmaier</name></noRegion><name sortKey="Albrecht, Eva" sort="Albrecht, Eva" uniqKey="Albrecht E" first="Eva" last="Albrecht">Eva Albrecht</name><name sortKey="Altmaier, Elisabeth" sort="Altmaier, Elisabeth" uniqKey="Altmaier E" first="Elisabeth" last="Altmaier">Elisabeth Altmaier</name><name sortKey="Altmaier, Elisabeth" sort="Altmaier, Elisabeth" uniqKey="Altmaier E" first="Elisabeth" last="Altmaier">Elisabeth Altmaier</name><name sortKey="Arndt, Volker" sort="Arndt, Volker" uniqKey="Arndt V" first="Volker" last="Arndt">Volker Arndt</name><name sortKey="Beckmann, Matthias W" sort="Beckmann, Matthias W" uniqKey="Beckmann M" first="Matthias W." last="Beckmann">Matthias W. Beckmann</name><name sortKey="Bogdanova, Natalia V" sort="Bogdanova, Natalia V" uniqKey="Bogdanova N" first="Natalia V." last="Bogdanova">Natalia V. Bogdanova</name><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name><name sortKey="Brauch, Hiltrud" sort="Brauch, Hiltrud" uniqKey="Brauch H" first="Hiltrud" last="Brauch">Hiltrud Brauch</name><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name><name sortKey="Brenner, Hermann" sort="Brenner, Hermann" uniqKey="Brenner H" first="Hermann" last="Brenner">Hermann Brenner</name><name sortKey="Bruning, Thomas" sort="Bruning, Thomas" uniqKey="Bruning T" first="Thomas" last="Brüning">Thomas Brüning</name><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name><name sortKey="Burwinkel, Barbara" sort="Burwinkel, Barbara" uniqKey="Burwinkel B" first="Barbara" last="Burwinkel">Barbara Burwinkel</name><name sortKey="Chang Claude, Jenny" sort="Chang Claude, Jenny" uniqKey="Chang Claude J" first="Jenny" last="Chang-Claude">Jenny Chang-Claude</name><name sortKey="Dork, Thilo" sort="Dork, Thilo" uniqKey="Dork T" first="Thilo" last="Dörk">Thilo Dörk</name><name sortKey="Fasching, Peter A" sort="Fasching, Peter A" uniqKey="Fasching P" first="Peter A." last="Fasching">Peter A. Fasching</name><name sortKey="Flesch Janys, Dieter" sort="Flesch Janys, Dieter" uniqKey="Flesch Janys D" first="Dieter" last="Flesch-Janys">Dieter Flesch-Janys</name><name sortKey="Flesch Janys, Dieter" sort="Flesch Janys, Dieter" uniqKey="Flesch Janys D" first="Dieter" last="Flesch-Janys">Dieter Flesch-Janys</name><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><name sortKey="Gieger, Christian" sort="Gieger, Christian" uniqKey="Gieger C" first="Christian" last="Gieger">Christian Gieger</name><name sortKey="Hamann, Ute" sort="Hamann, Ute" uniqKey="Hamann U" first="Ute" last="Hamann">Ute Hamann</name><name sortKey="Homuth, Georg" sort="Homuth, Georg" uniqKey="Homuth G" first="Georg" last="Homuth">Georg Homuth</name><name sortKey="Kabisch, Maria" sort="Kabisch, Maria" uniqKey="Kabisch M" first="Maria" last="Kabisch">Maria Kabisch</name><name sortKey="Kriebel, Jennifer" sort="Kriebel, Jennifer" uniqKey="Kriebel J" first="Jennifer" last="Kriebel">Jennifer Kriebel</name><name sortKey="Kriebel, Jennifer" sort="Kriebel, Jennifer" uniqKey="Kriebel J" first="Jennifer" last="Kriebel">Jennifer Kriebel</name><name sortKey="Kriebel, Jennifer" sort="Kriebel, Jennifer" uniqKey="Kriebel J" first="Jennifer" last="Kriebel">Jennifer Kriebel</name><name sortKey="Manz, Judith" sort="Manz, Judith" uniqKey="Manz J" first="Judith" last="Manz">Judith Manz</name><name sortKey="Manz, Judith" sort="Manz, Judith" uniqKey="Manz J" first="Judith" last="Manz">Judith Manz</name><name sortKey="Meindl, Alfons" sort="Meindl, Alfons" uniqKey="Meindl A" first="Alfons" last="Meindl">Alfons Meindl</name><name sortKey="Muller Nurasyid, Martina" sort="Muller Nurasyid, Martina" uniqKey="Muller Nurasyid M" first="Martina" last="Müller-Nurasyid">Martina Müller-Nurasyid</name><name sortKey="Muller Nurasyid, Martina" sort="Muller Nurasyid, Martina" uniqKey="Muller Nurasyid M" first="Martina" last="Müller-Nurasyid">Martina Müller-Nurasyid</name><name sortKey="Muller Nurasyid, Martina" sort="Muller Nurasyid, Martina" uniqKey="Muller Nurasyid M" first="Martina" last="Müller-Nurasyid">Martina Müller-Nurasyid</name><name sortKey="Petersmann, Astrid" sort="Petersmann, Astrid" uniqKey="Petersmann A" first="Astrid" last="Petersmann">Astrid Petersmann</name><name sortKey="Rudolph, Anja" sort="Rudolph, Anja" uniqKey="Rudolph A" first="Anja" last="Rudolph">Anja Rudolph</name><name sortKey="Schmidt, Frank" sort="Schmidt, Frank" uniqKey="Schmidt F" first="Frank" last="Schmidt">Frank Schmidt</name><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K." last="Schmutzler">Rita K. Schmutzler</name><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K." last="Schmutzler">Rita K. Schmutzler</name><name sortKey="Schmutzler, Rita K" sort="Schmutzler, Rita K" uniqKey="Schmutzler R" first="Rita K." last="Schmutzler">Rita K. Schmutzler</name><name sortKey="Stockl, Doris" sort="Stockl, Doris" uniqKey="Stockl D" first="Doris" last="Stöckl">Doris Stöckl</name><name sortKey="Strauch, Konstantin" sort="Strauch, Konstantin" uniqKey="Strauch K" first="Konstantin" last="Strauch">Konstantin Strauch</name><name sortKey="Strauch, Konstantin" sort="Strauch, Konstantin" uniqKey="Strauch K" first="Konstantin" last="Strauch">Konstantin Strauch</name><name sortKey="Teumer, Alexander" sort="Teumer, Alexander" uniqKey="Teumer A" first="Alexander" last="Teumer">Alexander Teumer</name><name sortKey="Volzke, Henry" sort="Volzke, Henry" uniqKey="Volzke H" first="Henry" last="Völzke">Henry Völzke</name><name sortKey="Zygmunt, Marek" sort="Zygmunt, Marek" uniqKey="Zygmunt M" first="Marek" last="Zygmunt">Marek Zygmunt</name></country><country name="Italie"><noRegion><name sortKey="Nutile, Teresa" sort="Nutile, Teresa" uniqKey="Nutile T" first="Teresa" last="Nutile">Teresa Nutile</name></noRegion><name sortKey="Barbieri, Caterina" sort="Barbieri, Caterina" uniqKey="Barbieri C" first="Caterina" last="Barbieri">Caterina Barbieri</name><name sortKey="Barbieri, Caterina" sort="Barbieri, Caterina" uniqKey="Barbieri C" first="Caterina" last="Barbieri">Caterina Barbieri</name><name sortKey="Ciullo, Marina" sort="Ciullo, Marina" uniqKey="Ciullo M" first="Marina" last="Ciullo">Marina Ciullo</name><name sortKey="Crisponi, Laura" sort="Crisponi, Laura" uniqKey="Crisponi L" first="Laura" last="Crisponi">Laura Crisponi</name><name sortKey="Gandin, Ilaria" sort="Gandin, Ilaria" uniqKey="Gandin I" first="Ilaria" last="Gandin">Ilaria Gandin</name><name sortKey="Gandin, Ilaria" sort="Gandin, Ilaria" uniqKey="Gandin I" first="Ilaria" last="Gandin">Ilaria Gandin</name><name sortKey="Gasparini, Paolo P" sort="Gasparini, Paolo P" uniqKey="Gasparini P" first="Paolo P." last="Gasparini">Paolo P. Gasparini</name><name sortKey="Gasparini, Paolo P" sort="Gasparini, Paolo P" uniqKey="Gasparini P" first="Paolo P." last="Gasparini">Paolo P. Gasparini</name><name sortKey="Girotto, Giorgia G" sort="Girotto, Giorgia G" uniqKey="Girotto G" first="Giorgia G." last="Girotto">Giorgia G. Girotto</name><name sortKey="Masciullo, Corrado" sort="Masciullo, Corrado" uniqKey="Masciullo C" first="Corrado" last="Masciullo">Corrado Masciullo</name><name sortKey="Peterlongo, Paolo" sort="Peterlongo, Paolo" uniqKey="Peterlongo P" first="Paolo" last="Peterlongo">Paolo Peterlongo</name><name sortKey="Pirastu, Nicola N" sort="Pirastu, Nicola N" uniqKey="Pirastu N" first="Nicola N." last="Pirastu">Nicola N. Pirastu</name><name sortKey="Pirastu, Nicola N" sort="Pirastu, Nicola N" uniqKey="Pirastu N" first="Nicola N." last="Pirastu">Nicola N. Pirastu</name><name sortKey="Pistis, Giorgio" sort="Pistis, Giorgio" uniqKey="Pistis G" first="Giorgio" last="Pistis">Giorgio Pistis</name><name sortKey="Pistis, Giorgio" sort="Pistis, Giorgio" uniqKey="Pistis G" first="Giorgio" last="Pistis">Giorgio Pistis</name><name sortKey="Porcu, Eleonora" sort="Porcu, Eleonora" uniqKey="Porcu E" first="Eleonora" last="Porcu">Eleonora Porcu</name><name sortKey="Porcu, Eleonora" sort="Porcu, Eleonora" uniqKey="Porcu E" first="Eleonora" last="Porcu">Eleonora Porcu</name><name sortKey="Radice, Paolo" sort="Radice, Paolo" uniqKey="Radice P" first="Paolo" last="Radice">Paolo Radice</name><name sortKey="Robino, Antonietta" sort="Robino, Antonietta" uniqKey="Robino A" first="Antonietta" last="Robino">Antonietta Robino</name><name sortKey="Ruggiero, Daniela" sort="Ruggiero, Daniela" uniqKey="Ruggiero D" first="Daniela" last="Ruggiero">Daniela Ruggiero</name><name sortKey="Sala, Cinzia F" sort="Sala, Cinzia F" uniqKey="Sala C" first="Cinzia F." last="Sala">Cinzia F. Sala</name><name sortKey="Sanna, Serena" sort="Sanna, Serena" uniqKey="Sanna S" first="Serena" last="Sanna">Serena Sanna</name><name sortKey="Sorice, Rossella" sort="Sorice, Rossella" uniqKey="Sorice R" first="Rossella" last="Sorice">Rossella Sorice</name><name sortKey="Toniolo, Daniela" sort="Toniolo, Daniela" uniqKey="Toniolo D" first="Daniela" last="Toniolo">Daniela Toniolo</name><name sortKey="Traglia, Michela" sort="Traglia, Michela" uniqKey="Traglia M" first="Michela" last="Traglia">Michela Traglia</name><name sortKey="Ulivi, Sheila" sort="Ulivi, Sheila" uniqKey="Ulivi S" first="Sheila" last="Ulivi">Sheila Ulivi</name><name sortKey="Vozzi, Diego" sort="Vozzi, Diego" uniqKey="Vozzi D" first="Diego" last="Vozzi">Diego Vozzi</name><name sortKey="Vuckovic, Dragana" sort="Vuckovic, Dragana" uniqKey="Vuckovic D" first="Dragana" last="Vuckovic">Dragana Vuckovic</name><name sortKey="Vuckovic, Dragana" sort="Vuckovic, Dragana" uniqKey="Vuckovic D" first="Dragana" last="Vuckovic">Dragana Vuckovic</name></country><country name="Suisse"><noRegion><name sortKey="Corre, Tanguy" sort="Corre, Tanguy" uniqKey="Corre T" first="Tanguy" last="Corre">Tanguy Corre</name></noRegion><name sortKey="Bergmann, Sven" sort="Bergmann, Sven" uniqKey="Bergmann S" first="Sven" last="Bergmann">Sven Bergmann</name><name sortKey="Bergmann, Sven" sort="Bergmann, Sven" uniqKey="Bergmann S" first="Sven" last="Bergmann">Sven Bergmann</name><name sortKey="Corre, Tanguy" sort="Corre, Tanguy" uniqKey="Corre T" first="Tanguy" last="Corre">Tanguy Corre</name></country><country name="Canada"><noRegion><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name></noRegion><name sortKey="Andrulis, Irene L" sort="Andrulis, Irene L" uniqKey="Andrulis I" first="Irene L." last="Andrulis">Irene L. Andrulis</name><name sortKey="Goldberg, Mark S" sort="Goldberg, Mark S" uniqKey="Goldberg M" first="Mark S." last="Goldberg">Mark S. Goldberg</name><name sortKey="Goldberg, Mark S" sort="Goldberg, Mark S" uniqKey="Goldberg M" first="Mark S." last="Goldberg">Mark S. Goldberg</name><name sortKey="Knight, Julia A" sort="Knight, Julia A" uniqKey="Knight J" first="Julia A." last="Knight">Julia A. Knight</name><name sortKey="Knight, Julia A" sort="Knight, Julia A" uniqKey="Knight J" first="Julia A." last="Knight">Julia A. Knight</name><name sortKey="Simard, Jacques" sort="Simard, Jacques" uniqKey="Simard J" first="Jacques" last="Simard">Jacques Simard</name></country><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benitez">Javier Benitez</name></region><name sortKey="Benitez, Javier" sort="Benitez, Javier" uniqKey="Benitez J" first="Javier" last="Benitez">Javier Benitez</name><name sortKey="Gonzalez Neira, Anna" sort="Gonzalez Neira, Anna" uniqKey="Gonzalez Neira A" first="Anna" last="González-Neira">Anna González-Neira</name></country><country name="Finlande"><noRegion><name sortKey="Blomqvist, Carl" sort="Blomqvist, Carl" uniqKey="Blomqvist C" first="Carl" last="Blomqvist">Carl Blomqvist</name></noRegion><name sortKey="Kosma, Veli Matti" sort="Kosma, Veli Matti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name><name sortKey="Kosma, Veli Matti" sort="Kosma, Veli Matti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name><name sortKey="Kosma, Veli Matti" sort="Kosma, Veli Matti" uniqKey="Kosma V" first="Veli-Matti" last="Kosma">Veli-Matti Kosma</name><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name><name sortKey="Mannermaa, Arto" sort="Mannermaa, Arto" uniqKey="Mannermaa A" first="Arto" last="Mannermaa">Arto Mannermaa</name><name sortKey="Nevanlinna, Heli" sort="Nevanlinna, Heli" uniqKey="Nevanlinna H" first="Heli" last="Nevanlinna">Heli Nevanlinna</name><name sortKey="Pylk S, Katri" sort="Pylk S, Katri" uniqKey="Pylk S K" first="Katri" last="Pylk S">Katri Pylk S</name><name sortKey="Pylk S, Katri" sort="Pylk S, Katri" uniqKey="Pylk S K" first="Katri" last="Pylk S">Katri Pylk S</name><name sortKey="Winqvist, Robert" sort="Winqvist, Robert" uniqKey="Winqvist R" first="Robert" last="Winqvist">Robert Winqvist</name><name sortKey="Winqvist, Robert" sort="Winqvist, Robert" uniqKey="Winqvist R" first="Robert" last="Winqvist">Robert Winqvist</name></country><country name="Danemark"><region name="Hovedstaden"><name sortKey="Bojesen, Stig E" sort="Bojesen, Stig E" uniqKey="Bojesen S" first="Stig E." last="Bojesen">Stig E. Bojesen</name></region><name sortKey="Bojesen, Stig E" sort="Bojesen, Stig E" uniqKey="Bojesen S" first="Stig E." last="Bojesen">Stig E. Bojesen</name><name sortKey="Nordestgaard, B Rge G" sort="Nordestgaard, B Rge G" uniqKey="Nordestgaard B" first="B Rge G." last="Nordestgaard">B Rge G. Nordestgaard</name><name sortKey="Nordestgaard, B Rge G" sort="Nordestgaard, B Rge G" uniqKey="Nordestgaard B" first="B Rge G." last="Nordestgaard">B Rge G. Nordestgaard</name></country><country name="Norvège"><region name="Østlandet"><name sortKey="Borresen Dale, Anne Lise" sort="Borresen Dale, Anne Lise" uniqKey="Borresen Dale A" first="Anne-Lise" last="Borresen-Dale">Anne-Lise Borresen-Dale</name></region><name sortKey="Borresen Dale, Anne Lise" sort="Borresen Dale, Anne Lise" uniqKey="Borresen Dale A" first="Anne-Lise" last="Borresen-Dale">Anne-Lise Borresen-Dale</name><name sortKey="Kristensen, Vessela" sort="Kristensen, Vessela" uniqKey="Kristensen V" first="Vessela" last="Kristensen">Vessela Kristensen</name><name sortKey="Kristensen, Vessela" sort="Kristensen, Vessela" uniqKey="Kristensen V" first="Vessela" last="Kristensen">Vessela Kristensen</name><name sortKey="Kristensen, Vessela" sort="Kristensen, Vessela" uniqKey="Kristensen V" first="Vessela" last="Kristensen">Vessela Kristensen</name></country><country name="Australie"><noRegion><name sortKey="Chenevix Trench, Georgia" sort="Chenevix Trench, Georgia" uniqKey="Chenevix Trench G" first="Georgia" last="Chenevix-Trench">Georgia Chenevix-Trench</name></noRegion><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G." last="Giles">Graham G. Giles</name><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G." last="Giles">Graham G. Giles</name><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L." last="Hopper">John L. Hopper</name><name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G." last="Martin">Nicholas G. Martin</name><name sortKey="Milne, Roger L" sort="Milne, Roger L" uniqKey="Milne R" first="Roger L." last="Milne">Roger L. Milne</name><name sortKey="Milne, Roger L" sort="Milne, Roger L" uniqKey="Milne R" first="Roger L." last="Milne">Roger L. Milne</name><name sortKey="Montgomery, Grant W" sort="Montgomery, Grant W" uniqKey="Montgomery G" first="Grant W." last="Montgomery">Grant W. Montgomery</name><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C." last="Southey">Melissa C. Southey</name></country><country name="Suède"><region name="Svealand"><name sortKey="Czene, Kamila" sort="Czene, Kamila" uniqKey="Czene K" first="Kamila" last="Czene">Kamila Czene</name></region><name sortKey="Darabi, Hatef" sort="Darabi, Hatef" uniqKey="Darabi H" first="Hatef" last="Darabi">Hatef Darabi</name><name sortKey="Hall, Per" sort="Hall, Per" uniqKey="Hall P" first="Per" last="Hall">Per Hall</name><name sortKey="Humphreys, Keith" sort="Humphreys, Keith" uniqKey="Humphreys K" first="Keith" last="Humphreys">Keith Humphreys</name><name sortKey="Li, Jingmei" sort="Li, Jingmei" uniqKey="Li J" first="Jingmei" last="Li">Jingmei Li</name><name sortKey="Margolin, Sara" sort="Margolin, Sara" uniqKey="Margolin S" first="Sara" last="Margolin">Sara Margolin</name></country><country name="France"><noRegion><name sortKey="Guenel, Pascal" sort="Guenel, Pascal" uniqKey="Guenel P" first="Pascal" last="Guénel">Pascal Guénel</name></noRegion><name sortKey="Guenel, Pascal" sort="Guenel, Pascal" uniqKey="Guenel P" first="Pascal" last="Guénel">Pascal Guénel</name><name sortKey="Truong, Therese" sort="Truong, Therese" uniqKey="Truong T" first="Thérèse" last="Truong">Thérèse Truong</name><name sortKey="Truong, Therese" sort="Truong, Therese" uniqKey="Truong T" first="Thérèse" last="Truong">Thérèse Truong</name></country><country name="République populaire de Chine"><noRegion><name sortKey="Huang, Jinyan" sort="Huang, Jinyan" uniqKey="Huang J" first="Jinyan" last="Huang">Jinyan Huang</name></noRegion></country><country name="Pologne"><noRegion><name sortKey="Jakubowska, Anna" sort="Jakubowska, Anna" uniqKey="Jakubowska A" first="Anna" last="Jakubowska">Anna Jakubowska</name></noRegion><name sortKey="Lubinski, Jan" sort="Lubinski, Jan" uniqKey="Lubinski J" first="Jan" last="Lubinski">Jan Lubinski</name></country><country name="Croatie"><noRegion><name sortKey="Kolcic, Ivana" sort="Kolcic, Ivana" uniqKey="Kolcic I" first="Ivana" last="Kolcic">Ivana Kolcic</name></noRegion><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polasek">Ozren Polasek</name><name sortKey="Zemunik, Tatijana" sort="Zemunik, Tatijana" uniqKey="Zemunik T" first="Tatijana" last="Zemunik">Tatijana Zemunik</name></country><country name="Belgique"><noRegion><name sortKey="Lambrechts, Diether" sort="Lambrechts, Diether" uniqKey="Lambrechts D" first="Diether" last="Lambrechts">Diether Lambrechts</name></noRegion><name sortKey="Lambrechts, Diether" sort="Lambrechts, Diether" uniqKey="Lambrechts D" first="Diether" last="Lambrechts">Diether Lambrechts</name><name sortKey="Neven, Patrick" sort="Neven, Patrick" uniqKey="Neven P" first="Patrick" last="Neven">Patrick Neven</name></country><country name="Grèce"><region name="Attique (région)"><name sortKey="Yannoukakos, Drakoulis" sort="Yannoukakos, Drakoulis" uniqKey="Yannoukakos D" first="Drakoulis" last="Yannoukakos">Drakoulis Yannoukakos</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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|texte= Large-scale genomic analyses link reproductive ageing to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair
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